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Items: 1 to 20 of 91

1.

Assembly and structural properties of glucocorticoid-induced TNF receptor ligand: Implications for function.

Chattopadhyay K, Ramagopal UA, Mukhopadhaya A, Malashkevich VN, Dilorenzo TP, Brenowitz M, Nathenson SG, Almo SC.

Proc Natl Acad Sci U S A. 2007 Dec 4;104(49):19452-7. Epub 2007 Nov 26.

2.

Human glucocorticoid-induced TNF receptor ligand regulates its signaling activity through multiple oligomerization states.

Zhou Z, Song X, Berezov A, Zhang G, Li Y, Zhang H, Murali R, Li B, Greene MI.

Proc Natl Acad Sci U S A. 2008 Apr 8;105(14):5465-70. doi: 10.1073/pnas.0711350105. Epub 2008 Mar 31.

3.

Evolution of GITRL immune function: murine GITRL exhibits unique structural and biochemical properties within the TNF superfamily.

Chattopadhyay K, Ramagopal UA, Brenowitz M, Nathenson SG, Almo SC.

Proc Natl Acad Sci U S A. 2008 Jan 15;105(2):635-40. doi: 10.1073/pnas.0710529105. Epub 2008 Jan 8.

4.

Identification of a new member of the tumor necrosis factor family and its receptor, a human ortholog of mouse GITR.

Gurney AL, Marsters SA, Huang RM, Pitti RM, Mark DT, Baldwin DT, Gray AM, Dowd AD, Brush AD, Heldens AD, Schow AD, Goddard AD, Wood WI, Baker KP, Godowski PJ, Ashkenazi A.

Curr Biol. 1999 Feb 25;9(4):215-8.

5.

Enhanced in vitro refolding of soluble human glucocorticoid-induced TNF receptor-related ligand.

Kovács E, Szilágyi L, Koncz G, Lányi S, Ábrahám B.

Appl Biochem Biotechnol. 2013 Jun;170(4):819-30. doi: 10.1007/s12010-013-0232-0. Epub 2013 Apr 24.

PMID:
23613116
6.

Structural basis for ligand-mediated mouse GITR activation.

Zhou Z, Tone Y, Song X, Furuuchi K, Lear JD, Waldmann H, Tone M, Greene MI, Murali R.

Proc Natl Acad Sci U S A. 2008 Jan 15;105(2):641-5. doi: 10.1073/pnas.0711206105. Epub 2008 Jan 4.

7.

Cancer immunoediting by GITR (glucocorticoid-induced TNF-related protein) ligand in humans: NK cell/tumor cell interactions.

Baltz KM, Krusch M, Bringmann A, Brossart P, Mayer F, Kloss M, Baessler T, Kumbier I, Peterfi A, Kupka S, Kroeber S, Menzel D, Radsak MP, Rammensee HG, Salih HR.

FASEB J. 2007 Aug;21(10):2442-54. Epub 2007 Mar 14.

PMID:
17360848
8.

1.8 A structure of murine GITR ligand dimer expressed in Drosophila melanogaster S2 cells.

Chattopadhyay K, Ramagopal UA, Nathenson SG, Almo SC.

Acta Crystallogr D Biol Crystallogr. 2009 May;65(Pt 5):434-9. doi: 10.1107/S0907444909005721. Epub 2009 Apr 18.

9.
10.

Pharmacological modulation of GITRL/GITR system: therapeutic perspectives.

Nocentini G, Ronchetti S, Petrillo MG, Riccardi C.

Br J Pharmacol. 2012 Apr;165(7):2089-99. doi: 10.1111/j.1476-5381.2011.01753.x. Review.

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13.

Glucocorticoid-induced TNFR-related (GITR) protein and its ligand in antitumor immunity: functional role and therapeutic modulation.

Placke T, Kopp HG, Salih HR.

Clin Dev Immunol. 2010;2010:239083. doi: 10.1155/2010/239083. Epub 2010 Sep 26. Review.

14.

GITR/GITRL: more than an effector T cell co-stimulatory system.

Nocentini G, Ronchetti S, Cuzzocrea S, Riccardi C.

Eur J Immunol. 2007 May;37(5):1165-9. Review.

15.

Glucocorticoid-induced TNFR-related protein (GITR) ligand modulates cytokine release and NK cell reactivity in chronic lymphocytic leukemia (CLL).

Buechele C, Baessler T, Wirths S, Schmohl JU, Schmiedel BJ, Salih HR.

Leukemia. 2012 May;26(5):991-1000. doi: 10.1038/leu.2011.313. Epub 2011 Nov 8.

PMID:
22064350
16.

Identification of a ligand for glucocorticoid-induced tumor necrosis factor receptor constitutively expressed in dendritic cells.

Yu KY, Kim HS, Song SY, Min SS, Jeong JJ, Youn BS.

Biochem Biophys Res Commun. 2003 Oct 17;310(2):433-8.

PMID:
14521928
17.

Glucocorticoid-induced tumour necrosis factor receptor (GITR) and its ligand (GITRL) in atopic dermatitis.

Baumgartner-Nielsen J, Vestergaard C, Thestrup-Pedersen K, Deleuran M, Deleuran B.

Acta Derm Venereol. 2006;86(5):393-8.

18.

Genetic and pharmacological inhibition of GITR-GITRL interaction reduces chronic lung injury induced by bleomycin instillation.

Cuzzocrea S, Ronchetti S, Genovese T, Mazzon E, Agostini M, Di Paola R, Esposito E, Muià C, Nocentini G, Riccardi C.

FASEB J. 2007 Jan;21(1):117-29. Epub 2006 Nov 29.

PMID:
17135359
19.

Induction of MMP-13 expression by soluble human glucocorticoid-induced tumor necrosis factor receptor in fibroblast-like synovial cells.

Kim SJ, Shin HH, Park SY, Lee DS, Lee EA, Cho SD, Cho HR, Miyazawa K, Choi HS.

Osteoarthritis Cartilage. 2006 Feb;14(2):146-53. Epub 2005 Oct 20.

20.

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