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Items: 1 to 20 of 113

1.

Ring1-mediated ubiquitination of H2A restrains poised RNA polymerase II at bivalent genes in mouse ES cells.

Stock JK, Giadrossi S, Casanova M, Brookes E, Vidal M, Koseki H, Brockdorff N, Fisher AG, Pombo A.

Nat Cell Biol. 2007 Dec;9(12):1428-35. Epub 2007 Nov 25.

PMID:
18037880
2.

Ring around the genes.

Spektor TM, Rice JC.

Nat Cell Biol. 2007 Dec;9(12):1343-4.

PMID:
18059356
3.

Ubiquitin E3 ligase Ring1b/Rnf2 of polycomb repressive complex 1 contributes to stable maintenance of mouse embryonic stem cells.

van der Stoop P, Boutsma EA, Hulsman D, Noback S, Heimerikx M, Kerkhoven RM, Voncken JW, Wessels LF, van Lohuizen M.

PLoS One. 2008 May 21;3(5):e2235. doi: 10.1371/journal.pone.0002235.

4.

Pluripotency factors and Polycomb Group proteins repress aryl hydrocarbon receptor expression in murine embryonic stem cells.

Ko CI, Wang Q, Fan Y, Xia Y, Puga A.

Stem Cell Res. 2014 Jan;12(1):296-308. doi: 10.1016/j.scr.2013.11.007. Epub 2013 Nov 16.

5.

Role of histone H2A ubiquitination in Polycomb silencing.

Wang H, Wang L, Erdjument-Bromage H, Vidal M, Tempst P, Jones RS, Zhang Y.

Nature. 2004 Oct 14;431(7010):873-8. Epub 2004 Sep 22.

PMID:
15386022
6.
7.

Embryonic stem cell-derived hemangioblasts remain epigenetically plastic and require PRC1 to prevent neural gene expression.

Mazzarella L, Jørgensen HF, Soza-Ried J, Terry AV, Pearson S, Lacaud G, Kouskoff V, Merkenschlager M, Fisher AG.

Blood. 2011 Jan 6;117(1):83-7. doi: 10.1182/blood-2010-03-273128. Epub 2010 Sep 28.

8.

Coordinated regulation of transcriptional repression by the RBP2 H3K4 demethylase and Polycomb-Repressive Complex 2.

Pasini D, Hansen KH, Christensen J, Agger K, Cloos PA, Helin K.

Genes Dev. 2008 May 15;22(10):1345-55. doi: 10.1101/gad.470008.

9.

A phosphorylated form of Mel-18 targets the Ring1B histone H2A ubiquitin ligase to chromatin.

Elderkin S, Maertens GN, Endoh M, Mallery DL, Morrice N, Koseki H, Peters G, Brockdorff N, Hiom K.

Mol Cell. 2007 Oct 12;28(1):107-20.

10.

Histone H2A monoubiquitination represses transcription by inhibiting RNA polymerase II transcriptional elongation.

Zhou W, Zhu P, Wang J, Pascual G, Ohgi KA, Lozach J, Glass CK, Rosenfeld MG.

Mol Cell. 2008 Jan 18;29(1):69-80. doi: 10.1016/j.molcel.2007.11.002.

11.

BAF250a Protein Regulates Nucleosome Occupancy and Histone Modifications in Priming Embryonic Stem Cell Differentiation.

Lei I, West J, Yan Z, Gao X, Fang P, Dennis JH, Gnatovskiy L, Wang W, Kingston RE, Wang Z.

J Biol Chem. 2015 Jul 31;290(31):19343-52. doi: 10.1074/jbc.M115.637389. Epub 2015 Jun 12.

12.

Recruitment of PRC1 function at the initiation of X inactivation independent of PRC2 and silencing.

Schoeftner S, Sengupta AK, Kubicek S, Mechtler K, Spahn L, Koseki H, Jenuwein T, Wutz A.

EMBO J. 2006 Jul 12;25(13):3110-22. Epub 2006 Jun 8.

13.

Fbxl10/Kdm2b recruits polycomb repressive complex 1 to CpG islands and regulates H2A ubiquitylation.

Wu X, Johansen JV, Helin K.

Mol Cell. 2013 Mar 28;49(6):1134-46. doi: 10.1016/j.molcel.2013.01.016. Epub 2013 Feb 7.

14.

Cooperation between EZH2, NSPc1-mediated histone H2A ubiquitination and Dnmt1 in HOX gene silencing.

Wu X, Gong Y, Yue J, Qiang B, Yuan J, Peng X.

Nucleic Acids Res. 2008 Jun;36(11):3590-9. doi: 10.1093/nar/gkn243. Epub 2008 May 6.

15.

RYBP-PRC1 complexes mediate H2A ubiquitylation at polycomb target sites independently of PRC2 and H3K27me3.

Tavares L, Dimitrova E, Oxley D, Webster J, Poot R, Demmers J, Bezstarosti K, Taylor S, Ura H, Koide H, Wutz A, Vidal M, Elderkin S, Brockdorff N.

Cell. 2012 Feb 17;148(4):664-78. doi: 10.1016/j.cell.2011.12.029. Epub 2012 Feb 9. Erratum in: Cell. 2012 Jun 22;149(7):1647-8.

16.

Histone H2A mono-ubiquitination is a crucial step to mediate PRC1-dependent repression of developmental genes to maintain ES cell identity.

Endoh M, Endo TA, Endoh T, Isono K, Sharif J, Ohara O, Toyoda T, Ito T, Eskeland R, Bickmore WA, Vidal M, Bernstein BE, Koseki H.

PLoS Genet. 2012;8(7):e1002774. doi: 10.1371/journal.pgen.1002774. Epub 2012 Jul 26.

17.

Role of polycomb proteins Ring1A and Ring1B in the epigenetic regulation of gene expression.

Vidal M.

Int J Dev Biol. 2009;53(2-3):355-70. doi: 10.1387/ijdb.082690mv. Review.

18.

Ring1B compacts chromatin structure and represses gene expression independent of histone ubiquitination.

Eskeland R, Leeb M, Grimes GR, Kress C, Boyle S, Sproul D, Gilbert N, Fan Y, Skoultchi AI, Wutz A, Bickmore WA.

Mol Cell. 2010 May 14;38(3):452-64. doi: 10.1016/j.molcel.2010.02.032.

19.

PRC1 and PRC2 are not required for targeting of H2A.Z to developmental genes in embryonic stem cells.

Illingworth RS, Botting CH, Grimes GR, Bickmore WA, Eskeland R.

PLoS One. 2012;7(4):e34848. doi: 10.1371/journal.pone.0034848. Epub 2012 Apr 9.

20.

Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains.

Ku M, Koche RP, Rheinbay E, Mendenhall EM, Endoh M, Mikkelsen TS, Presser A, Nusbaum C, Xie X, Chi AS, Adli M, Kasif S, Ptaszek LM, Cowan CA, Lander ES, Koseki H, Bernstein BE.

PLoS Genet. 2008 Oct;4(10):e1000242. doi: 10.1371/journal.pgen.1000242. Epub 2008 Oct 31.

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