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Mutations within potential glycosylation sites in the capsid protein of hepatitis E virus prevent the formation of infectious virus particles.

Graff J, Zhou YH, Torian U, Nguyen H, St Claire M, Yu C, Purcell RH, Emerson SU.

J Virol. 2008 Feb;82(3):1185-94. Epub 2007 Nov 21.


The hepatitis E virus capsid C-terminal region is essential for the viral life cycle: implication for viral genome encapsidation and particle stabilization.

Shiota T, Li TC, Yoshizaki S, Kato T, Wakita T, Ishii K.

J Virol. 2013 May;87(10):6031-6. doi: 10.1128/JVI.00444-13. Epub 2013 Mar 6.


Structure of hepatitis E virion-sized particle reveals an RNA-dependent viral assembly pathway.

Xing L, Li TC, Mayazaki N, Simon MN, Wall JS, Moore M, Wang CY, Takeda N, Wakita T, Miyamura T, Cheng RH.

J Biol Chem. 2010 Oct 22;285(43):33175-83. doi: 10.1074/jbc.M110.106336. Epub 2010 Aug 18.


The open reading frame 3 gene of hepatitis E virus contains a cis-reactive element and encodes a protein required for infection of macaques.

Graff J, Nguyen H, Yu C, Elkins WR, St Claire M, Purcell RH, Emerson SU.

J Virol. 2005 Jun;79(11):6680-9.


Structure of hepatitis E viral particle.

Mori Y, Matsuura Y.

Virus Res. 2011 Oct;161(1):59-64. doi: 10.1016/j.virusres.2011.03.015. Epub 2011 Apr 1. Review.


Dengue virus capsid protein usurps lipid droplets for viral particle formation.

Samsa MM, Mondotte JA, Iglesias NG, Assunção-Miranda I, Barbosa-Lima G, Da Poian AT, Bozza PT, Gamarnik AV.

PLoS Pathog. 2009 Oct;5(10):e1000632. doi: 10.1371/journal.ppat.1000632. Epub 2009 Oct 23.


Alanine scanning of poliovirus 2CATPase reveals new genetic evidence that capsid protein/2CATPase interactions are essential for morphogenesis.

Wang C, Jiang P, Sand C, Paul AV, Wimmer E.

J Virol. 2012 Sep;86(18):9964-75. doi: 10.1128/JVI.00914-12. Epub 2012 Jul 3.


Rubella virus-like replicon particles: analysis of encapsidation determinants and non-structural roles of capsid protein in early post-entry replication.

Claus C, Tzeng WP, Liebert UG, Frey TK.

J Gen Virol. 2012 Mar;93(Pt 3):516-25. doi: 10.1099/vir.0.038984-0. Epub 2011 Nov 23.


Mutation of Putative N-Glycosylation Sites on Dengue Virus NS4B Decreases RNA Replication.

Naik NG, Wu HN.

J Virol. 2015 Jul;89(13):6746-60. doi: 10.1128/JVI.00423-15. Epub 2015 Apr 15.


A Single Maturation Cleavage Site in Adenovirus Impacts Cell Entry and Capsid Assembly.

Moyer CL, Besser ES, Nemerow GR.

J Virol. 2015 Oct 21;90(1):521-32. doi: 10.1128/JVI.02014-15.


In vitro replication of hepatitis E virus (HEV) genomes and of an HEV replicon expressing green fluorescent protein.

Emerson SU, Nguyen H, Graff J, Stephany DA, Brockington A, Purcell RH.

J Virol. 2004 May;78(9):4838-46.


ORF3 protein of hepatitis E virus is not required for replication, virion assembly, or infection of hepatoma cells in vitro.

Emerson SU, Nguyen H, Torian U, Purcell RH.

J Virol. 2006 Nov;80(21):10457-64. Epub 2006 Aug 23.


Three amino acid mutations (F51L, T59A, and S390L) in the capsid protein of the hepatitis E virus collectively contribute to virus attenuation.

Córdoba L, Huang YW, Opriessnig T, Harral KK, Beach NM, Finkielstein CV, Emerson SU, Meng XJ.

J Virol. 2011 Jun;85(11):5338-49. doi: 10.1128/JVI.02278-10. Epub 2011 Mar 30.


Helices alpha2 and alpha3 of West Nile virus capsid protein are dispensable for assembly of infectious virions.

Schlick P, Taucher C, Schittl B, Tran JL, Kofler RM, Schueler W, von Gabain A, Meinke A, Mandl CW.

J Virol. 2009 Jun;83(11):5581-91. doi: 10.1128/JVI.02653-08. Epub 2009 Mar 18.


The SD1 Subdomain of Venezuelan Equine Encephalitis Virus Capsid Protein Plays a Critical Role in Nucleocapsid and Particle Assembly.

Reynaud JM, Lulla V, Kim DY, Frolova EI, Frolov I.

J Virol. 2015 Dec 9;90(4):2008-20. doi: 10.1128/JVI.02680-15.


Essential elements of the capsid protein for self-assembly into empty virus-like particles of hepatitis E virus.

Li TC, Takeda N, Miyamura T, Matsuura Y, Wang JC, Engvall H, Hammar L, Xing L, Cheng RH.

J Virol. 2005 Oct;79(20):12999-3006.

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