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Items: 1 to 20 of 178


Trf4 targets ncRNAs from telomeric and rDNA spacer regions and functions in rDNA copy number control.

Houseley J, Kotovic K, El Hage A, Tollervey D.

EMBO J. 2007 Dec 12;26(24):4996-5006.


Distinct roles of non-canonical poly(A) polymerases in RNA metabolism.

San Paolo S, Vanacova S, Schenk L, Scherrer T, Blank D, Keller W, Gerber AP.

PLoS Genet. 2009 Jul;5(7):e1000555. doi: 10.1371/journal.pgen.1000555.


Air1 zinc knuckles 4 and 5 and a conserved IWRXY motif are critical for the function and integrity of the Trf4/5-Air1/2-Mtr4 polyadenylation (TRAMP) RNA quality control complex.

Fasken MB, Leung SW, Banerjee A, Kodani MO, Chavez R, Bowman EA, Purohit MK, Rubinson ME, Rubinson EH, Corbett AH.

J Biol Chem. 2011 Oct 28;286(43):37429-45. doi: 10.1074/jbc.M111.271494.


Nab3 facilitates the function of the TRAMP complex in RNA processing via recruitment of Rrp6 independent of Nrd1.

Fasken MB, Laribee RN, Corbett AH.

PLoS Genet. 2015 Mar 16;11(3):e1005044. doi: 10.1371/journal.pgen.1005044.


Enforcement of a lifespan-sustaining distribution of Sir2 between telomeres, mating-type loci, and rDNA repeats by Rif1.

Salvi JS, Chan JN, Pettigrew C, Liu TT, Wu JD, Mekhail K.

Aging Cell. 2013 Feb;12(1):67-75. doi: 10.1111/acel.12020.


The nuclear RNA polymerase II surveillance system targets polymerase III transcripts.

Wlotzka W, Kudla G, Granneman S, Tollervey D.

EMBO J. 2011 May 4;30(9):1790-803. doi: 10.1038/emboj.2011.97. Erratum in: EMBO J. 2011;30(14):2982.


The exosome component Rrp6 is required for RNA polymerase II termination at specific targets of the Nrd1-Nab3 pathway.

Fox MJ, Gao H, Smith-Kinnaman WR, Liu Y, Mosley AL.

PLoS Genet. 2015 Feb 13;11(2):e1004999. doi: 10.1371/journal.pgen.1004999.


Molecular basis for coordinating transcription termination with noncoding RNA degradation.

Tudek A, Porrua O, Kabzinski T, Lidschreiber M, Kubicek K, Fortova A, Lacroute F, Vanacova S, Cramer P, Stefl R, Libri D.

Mol Cell. 2014 Aug 7;55(3):467-81. doi: 10.1016/j.molcel.2014.05.031.


A yeast exosome cofactor, Mpp6, functions in RNA surveillance and in the degradation of noncoding RNA transcripts.

Milligan L, Decourty L, Saveanu C, Rappsilber J, Ceulemans H, Jacquier A, Tollervey D.

Mol Cell Biol. 2008 Sep;28(17):5446-57. doi: 10.1128/MCB.00463-08.


TRAMP complex enhances RNA degradation by the nuclear exosome component Rrp6.

Callahan KP, Butler JS.

J Biol Chem. 2010 Feb 5;285(6):3540-7. doi: 10.1074/jbc.M109.058396.


RNA unwinding by the Trf4/Air2/Mtr4 polyadenylation (TRAMP) complex.

Jia H, Wang X, Anderson JT, Jankowsky E.

Proc Natl Acad Sci U S A. 2012 May 8;109(19):7292-7. doi: 10.1073/pnas.1201085109.


Exosome Cofactors Connect Transcription Termination to RNA Processing by Guiding Terminated Transcripts to the Appropriate Exonuclease within the Nuclear Exosome.

Kim K, Heo DH, Kim I, Suh JY, Kim M.

J Biol Chem. 2016 Jun 17;291(25):13229-42. doi: 10.1074/jbc.M116.715771.


Transcription termination and RNA degradation contribute to silencing of RNA polymerase II transcription within heterochromatin.

Vasiljeva L, Kim M, Terzi N, Soares LM, Buratowski S.

Mol Cell. 2008 Feb 15;29(3):313-23. doi: 10.1016/j.molcel.2008.01.011.


Termination of cryptic unstable transcripts is directed by yeast RNA-binding proteins Nrd1 and Nab3.

Arigo JT, Eyler DE, Carroll KL, Corden JL.

Mol Cell. 2006 Sep 15;23(6):841-51.


Global transcription regulation by DNA topoisomerase I in exponentially growing Saccharomyces cerevisiae cells: activation of telomere-proximal genes by TOP1 deletion.

Lotito L, Russo A, Chillemi G, Bueno S, Cavalieri D, Capranico G.

J Mol Biol. 2008 Mar 21;377(2):311-22. doi: 10.1016/j.jmb.2008.01.037.


Nop53p interacts with 5.8S rRNA co-transcriptionally, and regulates processing of pre-rRNA by the exosome.

Granato DC, Machado-Santelli GM, Oliveira CC.

FEBS J. 2008 Aug;275(16):4164-78. doi: 10.1111/j.1742-4658.2008.06565.x.

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