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Items: 1 to 20 of 47

1.

Uncovering therapeutic targets for glioblastoma: a systems biology approach.

Huang PH, Cavenee WK, Furnari FB, White FM.

Cell Cycle. 2007 Nov 15;6(22):2750-4. Epub 2007 Aug 20. Review.

PMID:
17986864
2.

JAK2/STAT3 targeted therapy suppresses tumor invasion via disruption of the EGFRvIII/JAK2/STAT3 axis and associated focal adhesion in EGFRvIII-expressing glioblastoma.

Zheng Q, Han L, Dong Y, Tian J, Huang W, Liu Z, Jia X, Jiang T, Zhang J, Li X, Kang C, Ren H.

Neuro Oncol. 2014 Sep;16(9):1229-43. doi: 10.1093/neuonc/nou046. Epub 2014 May 25.

3.

Targeting EGFR for treatment of glioblastoma: molecular basis to overcome resistance.

Taylor TE, Furnari FB, Cavenee WK.

Curr Cancer Drug Targets. 2012 Mar;12(3):197-209. Review.

4.

Deregulated signaling pathways in glioblastoma multiforme: molecular mechanisms and therapeutic targets.

Mao H, Lebrun DG, Yang J, Zhu VF, Li M.

Cancer Invest. 2012 Jan;30(1):48-56. doi: 10.3109/07357907.2011.630050. Review.

5.

Quantitative analysis of EGFRvIII cellular signaling networks reveals a combinatorial therapeutic strategy for glioblastoma.

Huang PH, Mukasa A, Bonavia R, Flynn RA, Brewer ZE, Cavenee WK, Furnari FB, White FM.

Proc Natl Acad Sci U S A. 2007 Jul 31;104(31):12867-72. Epub 2007 Jul 23.

6.

The EGFRvIII variant in glioblastoma multiforme.

Gan HK, Kaye AH, Luwor RB.

J Clin Neurosci. 2009 Jun;16(6):748-54. doi: 10.1016/j.jocn.2008.12.005. Epub 2009 Mar 25. Review.

PMID:
19324552
7.

Targeting ErbB receptors in high-grade glioma.

Berezowska S, Schlegel J.

Curr Pharm Des. 2011;17(23):2468-87. Review.

PMID:
21827413
8.
9.

Epigenetic pathways and glioblastoma treatment: insights from signaling cascades.

Allen BK, Stathias V, Maloof ME, Vidovic D, Winterbottom EF, Capobianco AJ, Clarke J, Schurer S, Robbins DJ, Ayad NG.

J Cell Biochem. 2015 Mar;116(3):351-63. doi: 10.1002/jcb.24990. Review.

PMID:
25290986
10.

Network pharmacology of glioblastoma.

Aguda BD.

Curr Drug Discov Technol. 2013 Jun;10(2):125-38. Review.

PMID:
23237675
11.

Candidate genes influencing sensitivity and resistance of human glioblastoma to Semustine.

Zhao Z, Liu Y, He H, Chen X, Chen J, Lu YC.

Brain Res Bull. 2011 Oct 10;86(3-4):189-94. doi: 10.1016/j.brainresbull.2011.07.010. Epub 2011 Jul 22.

PMID:
21807073
12.
13.

Differentiation of glioblastoma multiforme stem-like cells leads to downregulation of EGFR and EGFRvIII and decreased tumorigenic and stem-like cell potential.

Stockhausen MT, Kristoffersen K, Stobbe L, Poulsen HS.

Cancer Biol Ther. 2014 Feb;15(2):216-24. doi: 10.4161/cbt.26736. Epub 2013 Nov 1.

14.

Crosstalk between the urokinase-type plasminogen activator receptor and EGF receptor variant III supports survival and growth of glioblastoma cells.

Hu J, Jo M, Cavenee WK, Furnari F, VandenBerg SR, Gonias SL.

Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):15984-9. doi: 10.1073/pnas.1113416108. Epub 2011 Sep 6.

15.

Cyclooxygenase-2 is a novel transcriptional target of the nuclear EGFR-STAT3 and EGFRvIII-STAT3 signaling axes.

Lo HW, Cao X, Zhu H, Ali-Osman F.

Mol Cancer Res. 2010 Feb;8(2):232-45. doi: 10.1158/1541-7786.MCR-09-0391. Epub 2010 Feb 9.

16.

HER1/EGFR tyrosine kinase inhibitors for the treatment of glioblastoma multiforme.

Raizer JJ.

J Neurooncol. 2005 Aug;74(1):77-86. Review.

PMID:
16078112
17.

Targeting ╬▓III-tubulin in glioblastoma multiforme: from cell biology and histopathology to cancer therapeutics.

Katsetos CD, Draber P, Kavallaris M.

Anticancer Agents Med Chem. 2011 Oct;11(8):719-28. Review.

PMID:
21707498
18.

Clipping the Wings of Glioblastoma: Modulation of WNT as a Novel Therapeutic Strategy.

Suwala AK, Hanaford A, Kahlert UD, Maciaczyk J.

J Neuropathol Exp Neurol. 2016 May;75(5):388-96. doi: 10.1093/jnen/nlw013. Epub 2016 Mar 15. Review.

PMID:
26979081
19.

Suppression of G-protein-coupled receptor kinase 3 expression is a feature of classical GBM that is required for maximal growth.

Woerner BM, Luo J, Brown KR, Jackson E, Dahiya SM, Mischel P, Benovic JL, Piwnica-Worms D, Rubin JB.

Mol Cancer Res. 2012 Jan;10(1):156-66. doi: 10.1158/1541-7786.MCR-11-0411. Epub 2011 Nov 15.

20.

Cellular signaling molecules as therapeutic targets in glioblastoma multiforme.

Jagannathan J, Prevedello DM, Dumont AS, Laws ER.

Neurosurg Focus. 2006 Apr 15;20(4):E8. Review.

PMID:
16709039

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