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Items: 1 to 20 of 138

1.

Bmi-1 cooperates with H-Ras to transform human mammary epithelial cells via dysregulation of multiple growth-regulatory pathways.

Datta S, Hoenerhoff MJ, Bommi P, Sainger R, Guo WJ, Dimri M, Band H, Band V, Green JE, Dimri GP.

Cancer Res. 2007 Nov 1;67(21):10286-95.

2.

BMI1 cooperates with H-RAS to induce an aggressive breast cancer phenotype with brain metastases.

Hoenerhoff MJ, Chu I, Barkan D, Liu ZY, Datta S, Dimri GP, Green JE.

Oncogene. 2009 Aug 27;28(34):3022-32. doi: 10.1038/onc.2009.165. Epub 2009 Jun 22.

3.

Bmi-1 promotes invasion and metastasis, and its elevated expression is correlated with an advanced stage of breast cancer.

Guo BH, Feng Y, Zhang R, Xu LH, Li MZ, Kung HF, Song LB, Zeng MS.

Mol Cancer. 2011 Jan 28;10(1):10. doi: 10.1186/1476-4598-10-10.

4.

The cell cycle regulator ecdysoneless cooperates with H-Ras to promote oncogenic transformation of human mammary epithelial cells.

Bele A, Mirza S, Zhang Y, Ahmad Mir R, Lin S, Kim JH, Gurumurthy CB, West W, Qiu F, Band H, Band V.

Cell Cycle. 2015;14(7):990-1000. doi: 10.1080/15384101.2015.1006982.

5.

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus.

Jacobs JJ, Kieboom K, Marino S, DePinho RA, van Lohuizen M.

Nature. 1999 Jan 14;397(6715):164-8.

PMID:
9923679
6.

The Ras oncogene signals centrosome amplification in mammary epithelial cells through cyclin D1/Cdk4 and Nek2.

Zeng X, Shaikh FY, Harrison MK, Adon AM, Trimboli AJ, Carroll KA, Sharma N, Timmers C, Chodosh LA, Leone G, Saavedra HI.

Oncogene. 2010 Sep 9;29(36):5103-12. doi: 10.1038/onc.2010.253. Epub 2010 Jun 28.

7.

ELF4/MEF activates MDM2 expression and blocks oncogene-induced p16 activation to promote transformation.

Sashida G, Liu Y, Elf S, Miyata Y, Ohyashiki K, Izumi M, Menendez S, Nimer SD.

Mol Cell Biol. 2009 Jul;29(13):3687-99. doi: 10.1128/MCB.01551-08. Epub 2009 Apr 20.

8.

Activation of the Raf-1/MAP kinase cascade is not sufficient for Ras transformation of RIE-1 epithelial cells.

Oldham SM, Clark GJ, Gangarosa LM, Coffey RJ Jr, Der CJ.

Proc Natl Acad Sci U S A. 1996 Jul 9;93(14):6924-8.

9.

Oncogenic ras and p53 cooperate to induce cellular senescence.

Ferbeyre G, de Stanchina E, Lin AW, Querido E, McCurrach ME, Hannon GJ, Lowe SW.

Mol Cell Biol. 2002 May;22(10):3497-508.

10.

BMI-1 promotes ewing sarcoma tumorigenicity independent of CDKN2A repression.

Douglas D, Hsu JH, Hung L, Cooper A, Abdueva D, van Doorninck J, Peng G, Shimada H, Triche TJ, Lawlor ER.

Cancer Res. 2008 Aug 15;68(16):6507-15. doi: 10.1158/0008-5472.CAN-07-6152.

11.

Combined loss of INK4a and caveolin-1 synergistically enhances cell proliferation and oncogene-induced tumorigenesis: role of INK4a/CAV-1 in mammary epithelial cell hyperplasia.

Williams TM, Lee H, Cheung MW, Cohen AW, Razani B, Iyengar P, Scherer PE, Pestell RG, Lisanti MP.

J Biol Chem. 2004 Jun 4;279(23):24745-56. Epub 2004 Mar 25.

12.

The bmi-1 oncoprotein is differentially expressed in non-small cell lung cancer and correlates with INK4A-ARF locus expression.

Vonlanthen S, Heighway J, Altermatt HJ, Gugger M, Kappeler A, Borner MM, van Lohuizen M, Betticher DC.

Br J Cancer. 2001 May 18;84(10):1372-6.

13.

Mel-18 negatively regulates INK4a/ARF-independent cell cycle progression via Akt inactivation in breast cancer.

Lee JY, Jang KS, Shin DH, Oh MY, Kim HJ, Kim Y, Kong G.

Cancer Res. 2008 Jun 1;68(11):4201-9. doi: 10.1158/0008-5472.CAN-07-2570.

14.

Opposite effects of Ha-Ras and Ki-Ras on radiation-induced apoptosis via differential activation of PI3K/Akt and Rac/p38 mitogen-activated protein kinase signaling pathways.

Choi JA, Park MT, Kang CM, Um HD, Bae S, Lee KH, Kim TH, Kim JH, Cho CK, Lee YS, Chung HY, Lee SJ.

Oncogene. 2004 Jan 8;23(1):9-20.

PMID:
14712206
15.
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17.

Oncogene-induced senescence does not require the p16(INK4a) or p14ARF melanoma tumor suppressors.

Haferkamp S, Scurr LL, Becker TM, Frausto M, Kefford RF, Rizos H.

J Invest Dermatol. 2009 Aug;129(8):1983-91. doi: 10.1038/jid.2009.5. Epub 2009 Feb 12.

18.
19.

Collagen I regulates the self-renewal of mouse embryonic stem cells through α2β1 integrin- and DDR1-dependent Bmi-1.

Suh HN, Han HJ.

J Cell Physiol. 2011 Dec;226(12):3422-32. doi: 10.1002/jcp.22697.

PMID:
21344393
20.

Tumor induction by an endogenous K-ras oncogene is highly dependent on cellular context.

Guerra C, Mijimolle N, Dhawahir A, Dubus P, Barradas M, Serrano M, Campuzano V, Barbacid M.

Cancer Cell. 2003 Aug;4(2):111-20.

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