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Items: 1 to 20 of 143

1.

Fatty acid synthase inhibitors: new directions for oncology.

Kridel SJ, Lowther WT, Pemble CW 4th.

Expert Opin Investig Drugs. 2007 Nov;16(11):1817-29. Review.

PMID:
17970640
2.
3.

Fatty acid synthase activity in tumor cells.

Little JL, Kridel SJ.

Subcell Biochem. 2008;49:169-94. doi: 10.1007/978-1-4020-8831-5_7. Review.

PMID:
18751912
4.

Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis.

Menendez JA, Lupu R.

Nat Rev Cancer. 2007 Oct;7(10):763-77. Review.

PMID:
17882277
5.

High prevalence of fatty acid synthase expression in colorectal cancers in Middle Eastern patients and its potential role as a therapeutic target.

Uddin S, Hussain AR, Ahmed M, Abubaker J, Al-Sanea N, Abduljabbar A, Ashari LH, Alhomoud S, Al-Dayel F, Bavi P, Al-Kuraya KS.

Am J Gastroenterol. 2009 Jul;104(7):1790-801. doi: 10.1038/ajg.2009.230. Epub 2009 Jun 2.

PMID:
19491830
6.

Inhibition of fatty acid synthase activity in prostate cancer cells by dutasteride.

Schmidt LJ, Ballman KV, Tindall DJ.

Prostate. 2007 Jul 1;67(10):1111-20.

PMID:
17477363
7.

Analyzing effects of extra-virgin olive oil polyphenols on breast cancer-associated fatty acid synthase protein expression using reverse-phase protein microarrays.

Menendez JA, Vazquez-Martin A, Oliveras-Ferraros C, Garcia-Villalba R, Carrasco-Pancorbo A, Fernandez-Gutierrez A, Segura-Carretero A.

Int J Mol Med. 2008 Oct;22(4):433-9.

PMID:
18813848
8.

Overexpression of fatty acid synthase gene activates HER1/HER2 tyrosine kinase receptors in human breast epithelial cells.

Vazquez-Martin A, Colomer R, Brunet J, Lupu R, Menendez JA.

Cell Prolif. 2008 Feb;41(1):59-85. doi: 10.1111/j.1365-2184.2007.00498.x.

PMID:
18211286
9.
10.

Inhibition of fatty acid synthase suppresses c-Met receptor kinase and induces apoptosis in diffuse large B-cell lymphoma.

Uddin S, Hussain AR, Ahmed M, Bu R, Ahmed SO, Ajarim D, Al-Dayel F, Bavi P, Al-Kuraya KS.

Mol Cancer Ther. 2010 May;9(5):1244-55. doi: 10.1158/1535-7163.MCT-09-1061. Epub 2010 Apr 27.

11.

Novel antagonists of the thioesterase domain of human fatty acid synthase.

Richardson RD, Smith JW.

Mol Cancer Ther. 2007 Jul;6(7):2120-6.

12.

Anti-cancer drugs targeting fatty acid synthase (FAS).

Pandey PR, Liu W, Xing F, Fukuda K, Watabe K.

Recent Pat Anticancer Drug Discov. 2012 May 1;7(2):185-97. Review.

PMID:
22338595
13.

Hyperglycaemia confers resistance to chemotherapy on breast cancer cells: the role of fatty acid synthase.

Zeng L, Biernacka KM, Holly JM, Jarrett C, Morrison AA, Morgan A, Winters ZE, Foulstone EJ, Shield JP, Perks CM.

Endocr Relat Cancer. 2010 May 18;17(2):539-51. doi: 10.1677/ERC-09-0221. Print 2010 Jun.

14.

Fatty acid metabolism in breast cancer cells: differential inhibitory effects of epigallocatechin gallate (EGCG) and C75.

Puig T, Vázquez-Martín A, Relat J, Pétriz J, Menéndez JA, Porta R, Casals G, Marrero PF, Haro D, Brunet J, Colomer R.

Breast Cancer Res Treat. 2008 Jun;109(3):471-9. Epub 2007 Sep 28.

PMID:
17902053
15.

Fatty-acid synthase and human cancer: new perspectives on its role in tumor biology.

Kuhajda FP.

Nutrition. 2000 Mar;16(3):202-8. Review.

PMID:
10705076
16.

Dietary soy protein inhibits DNA damage and cell survival of colon epithelial cells through attenuated expression of fatty acid synthase.

Xiao R, Su Y, Simmen RC, Simmen FA.

Am J Physiol Gastrointest Liver Physiol. 2008 Apr;294(4):G868-76. doi: 10.1152/ajpgi.00515.2007. Epub 2008 Jan 31.

17.

A new mechanism of drug resistance in breast cancer cells: fatty acid synthase overexpression-mediated palmitate overproduction.

Liu H, Liu Y, Zhang JT.

Mol Cancer Ther. 2008 Feb;7(2):263-70. doi: 10.1158/1535-7163.MCT-07-0445.

18.

Selective inhibition of fatty acid synthase for lung cancer treatment.

Orita H, Coulter J, Lemmon C, Tully E, Vadlamudi A, Medghalchi SM, Kuhajda FP, Gabrielson E.

Clin Cancer Res. 2007 Dec 1;13(23):7139-45. Epub 2007 Dec 3.

19.

New synthetic inhibitors of fatty acid synthase with anticancer activity.

Turrado C, Puig T, García-Cárceles J, Artola M, Benhamú B, Ortega-Gutiérrez S, Relat J, Oliveras G, Blancafort A, Haro D, Marrero PF, Colomer R, López-Rodríguez ML.

J Med Chem. 2012 Jun 14;55(11):5013-23. doi: 10.1021/jm2016045. Epub 2012 May 16.

PMID:
22559865
20.

Novel anti-fatty acid synthase compounds with anti-cancer activity in HER2+ breast cancer.

Oliveras G, Blancafort A, Urruticoechea A, Campuzano O, Gómez-Cabello D, Brugada R, López-Rodríguez ML, Colomer R, Puig T.

Ann N Y Acad Sci. 2010 Oct;1210:86-92. doi: 10.1111/j.1749-6632.2010.05777.x.

PMID:
20973802

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