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Items: 1 to 20 of 138

1.

A lack of thyroid hormones rather than excess thyrotropin causes abnormal skeletal development in hypothyroidism.

Bassett JH, Williams AJ, Murphy E, Boyde A, Howell PG, Swinhoe R, Archanco M, Flamant F, Samarut J, Costagliola S, Vassart G, Weiss RE, Refetoff S, Williams GR.

Mol Endocrinol. 2008 Feb;22(2):501-12. Epub 2007 Oct 11.

2.

Excess TSH causes abnormal skeletal development in young mice with hypothyroidism via suppressive effects on the growth plate.

Endo T, Kobayashi T.

Am J Physiol Endocrinol Metab. 2013 Sep 1;305(5):E660-6. doi: 10.1152/ajpendo.00067.2013. Epub 2013 Jul 23.

PMID:
23880310
3.

Role of the thyroid-stimulating hormone receptor signaling in development and differentiation of the thyroid gland.

Postiglione MP, Parlato R, Rodriguez-Mallon A, Rosica A, Mithbaokar P, Maresca M, Marians RC, Davies TF, Zannini MS, De Felice M, Di Lauro R.

Proc Natl Acad Sci U S A. 2002 Nov 26;99(24):15462-7. Epub 2002 Nov 13.

4.

The site of the molecular defect in the thyroid gland of the hyt/hyt mouse: abnormalities in the TSH receptor-G protein complex.

Stein SA, Zakarija M, McKenzie JM, Shanklin DR, Palnitkar MB, Adams PM.

Thyroid. 1991 Summer;1(3):257-66.

PMID:
1668617
5.

Expression of functional TSH receptor in white adipose tissues of hyt/hyt mice induces lipolysis in vivo.

Endo T, Kobayashi T.

Am J Physiol Endocrinol Metab. 2012 Jun 15;302(12):E1569-75. doi: 10.1152/ajpendo.00572.2011. Epub 2012 Apr 10.

PMID:
22496347
6.

Effects of thyroid status on bone metabolism: a primary role for thyroid stimulating hormone or thyroid hormone?

Galliford TM, Murphy E, Williams AJ, Bassett JH, Williams GR.

Minerva Endocrinol. 2005 Dec;30(4):237-46. Review.

PMID:
16319811
7.

Dominant negative effect of mutated thyroid stimulating hormone receptor (P556L) causes hypothyroidism in C.RF-Tshr(hyt/wild) mice.

Endo T, Kobayashi T.

PLoS One. 2012;7(8):e42358. doi: 10.1371/journal.pone.0042358. Epub 2012 Aug 16.

8.

Evaluation and characterization of the hyt/hyt hypothyroid mouse. II. Abnormalities of TSH and the thyroid gland.

Stein SA, Shanklin DR, Krulich L, Roth MG, Chubb CM, Adams PM.

Neuroendocrinology. 1989 May;49(5):509-19.

PMID:
2725843
9.

TSH is a negative regulator of skeletal remodeling.

Abe E, Marians RC, Yu W, Wu XB, Ando T, Li Y, Iqbal J, Eldeiry L, Rajendren G, Blair HC, Davies TF, Zaidi M.

Cell. 2003 Oct 17;115(2):151-62.

10.

The influence of thyroid-stimulating hormone and thyroid-stimulating hormone receptor antibodies on osteoclastogenesis.

Ma R, Morshed S, Latif R, Zaidi M, Davies TF.

Thyroid. 2011 Aug;21(8):897-906. doi: 10.1089/thy.2010.0457. Epub 2011 Jul 11.

11.

Thyroid-stimulating hormone maintains bone mass and strength by suppressing osteoclast differentiation.

Zhang W, Zhang Y, Liu Y, Wang J, Gao L, Yu C, Yan H, Zhao J, Xu J.

J Biomech. 2014 Apr 11;47(6):1307-14. doi: 10.1016/j.jbiomech.2014.02.015. Epub 2014 Feb 19.

PMID:
24629929
12.

Critical role of the hypothalamic-pituitary-thyroid axis in bone.

Bassett JH, Williams GR.

Bone. 2008 Sep;43(3):418-26. doi: 10.1016/j.bone.2008.05.007. Epub 2008 May 16. Review.

PMID:
18585995
13.

Defining thyrotropin-dependent and -independent steps of thyroid hormone synthesis by using thyrotropin receptor-null mice.

Marians RC, Ng L, Blair HC, Unger P, Graves PN, Davies TF.

Proc Natl Acad Sci U S A. 2002 Nov 26;99(24):15776-81. Epub 2002 Nov 13. Erratum in: Proc Natl Acad Sci U S A. 2005 Jan 11;102(2):515.

14.

Actions of thyroid hormones in bone.

Williams GR.

Endokrynol Pol. 2009 Sep-Oct;60(5):380-8. Review.

PMID:
19885809
15.

Thyroid-stimulating hormone restores bone volume, microarchitecture, and strength in aged ovariectomized rats.

Sampath TK, Simic P, Sendak R, Draca N, Bowe AE, O'Brien S, Schiavi SC, McPherson JM, Vukicevic S.

J Bone Miner Res. 2007 Jun;22(6):849-59.

16.

Loss of MMP-2 disrupts skeletal and craniofacial development and results in decreased bone mineralization, joint erosion and defects in osteoblast and osteoclast growth.

Mosig RA, Dowling O, DiFeo A, Ramirez MC, Parker IC, Abe E, Diouri J, Aqeel AA, Wylie JD, Oblander SA, Madri J, Bianco P, Apte SS, Zaidi M, Doty SB, Majeska RJ, Schaffler MB, Martignetti JA.

Hum Mol Genet. 2007 May 1;16(9):1113-23. Epub 2007 Mar 30.

17.

Osteoblast extracellular Ca2+ -sensing receptor regulates bone development, mineralization, and turnover.

Dvorak-Ewell MM, Chen TH, Liang N, Garvey C, Liu B, Tu C, Chang W, Bikle DD, Shoback DM.

J Bone Miner Res. 2011 Dec;26(12):2935-47. doi: 10.1002/jbmr.520.

18.

Thyroid follicle formation and thyroglobulin expression in multipotent endodermal stem cells.

Ma R, Latif R, Davies TF.

Thyroid. 2013 Apr;23(4):385-91. doi: 10.1089/thy.2012.0644. Epub 2013 Mar 18.

19.

Thyroid and bone.

Gogakos AI, Duncan Bassett JH, Williams GR.

Arch Biochem Biophys. 2010 Nov 1;503(1):129-36. doi: 10.1016/j.abb.2010.06.021. Epub 2010 Jun 23. Review.

PMID:
20599658
20.

The thyroid hormone receptor beta-specific agonist GC-1 selectively affects the bone development of hypothyroid rats.

Freitas FR, Capelo LP, O'Shea PJ, Jorgetti V, Moriscot AS, Scanlan TS, Williams GR, Zorn TM, Gouveia CH.

J Bone Miner Res. 2005 Feb;20(2):294-304. Epub 2004 Nov 22.

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