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Items: 1 to 20 of 121

1.
2.

Broad-spectrum antimicrobial peptides by rational combinatorial design and high-throughput screening: the importance of interfacial activity.

Rathinakumar R, Walkenhorst WF, Wimley WC.

J Am Chem Soc. 2009 Jun 10;131(22):7609-17. doi: 10.1021/ja8093247.

4.

Synthetic molecular evolution of pore-forming peptides by iterative combinatorial library screening.

Krauson AJ, He J, Wimley AW, Hoffmann AR, Wimley WC.

ACS Chem Biol. 2013 Apr 19;8(4):823-31. doi: 10.1021/cb300598k. Epub 2013 Feb 20.

5.

Rational combinatorial design of pore-forming beta-sheet peptides.

Rausch JM, Marks JR, Wimley WC.

Proc Natl Acad Sci U S A. 2005 Jul 26;102(30):10511-5. Epub 2005 Jul 14.

6.
7.

Direct visualization of membrane leakage induced by the antibiotic peptides: maculatin, citropin, and aurein.

Ambroggio EE, Separovic F, Bowie JH, Fidelio GD, Bagatolli LA.

Biophys J. 2005 Sep;89(3):1874-81. Epub 2005 Jul 1.

8.

Mechanism of antibacterial action of dermaseptin B2: interplay between helix-hinge-helix structure and membrane curvature strain.

Galanth C, Abbassi F, Lequin O, Ayala-Sanmartin J, Ladram A, Nicolas P, Amiche M.

Biochemistry. 2009 Jan 20;48(2):313-27. doi: 10.1021/bi802025a.

PMID:
19113844
9.
10.

Highly efficient macromolecule-sized poration of lipid bilayers by a synthetically evolved peptide.

Wiedman G, Fuselier T, He J, Searson PC, Hristova K, Wimley WC.

J Am Chem Soc. 2014 Mar 26;136(12):4724-31. doi: 10.1021/ja500462s. Epub 2014 Mar 13.

11.

Molecular mechanism of action of β-hairpin antimicrobial peptide arenicin: oligomeric structure in dodecylphosphocholine micelles and pore formation in planar lipid bilayers.

Shenkarev ZO, Balandin SV, Trunov KI, Paramonov AS, Sukhanov SV, Barsukov LI, Arseniev AS, Ovchinnikova TV.

Biochemistry. 2011 Jul 19;50(28):6255-65. doi: 10.1021/bi200746t. Epub 2011 Jun 24.

PMID:
21627330
12.

Biomolecular engineering by combinatorial design and high-throughput screening: small, soluble peptides that permeabilize membranes.

Rathinakumar R, Wimley WC.

J Am Chem Soc. 2008 Jul 30;130(30):9849-58. doi: 10.1021/ja8017863. Epub 2008 Jul 9.

13.

Gain-of-function analogues of the pore-forming peptide melittin selected by orthogonal high-throughput screening.

Krauson AJ, He J, Wimley WC.

J Am Chem Soc. 2012 Aug 1;134(30):12732-41. doi: 10.1021/ja3042004. Epub 2012 Jul 18.

16.

How Membrane-Active Peptides Get into Lipid Membranes.

Sani MA, Separovic F.

Acc Chem Res. 2016 Jun 21;49(6):1130-8. doi: 10.1021/acs.accounts.6b00074. Epub 2016 May 17. Review.

PMID:
27187572
17.

Interactions of an antimicrobial peptide, tachyplesin I, with lipid membranes.

Matsuzaki K, Fukui M, Fujii N, Miyajima K.

Biochim Biophys Acta. 1991 Nov 18;1070(1):259-64.

PMID:
1751532
18.

The interaction of the antimicrobial peptide gramicidin S with lipid bilayer model and biological membranes.

Prenner EJ, Lewis RN, McElhaney RN.

Biochim Biophys Acta. 1999 Dec 15;1462(1-2):201-21. Review.

19.

The importance of membrane defects-lessons from simulations.

Bennett WF, Tieleman DP.

Acc Chem Res. 2014 Aug 19;47(8):2244-51. doi: 10.1021/ar4002729. Epub 2014 Jun 3.

PMID:
24892900
20.

Pore-forming peptides induce rapid phospholipid flip-flop in membranes.

Fattal E, Nir S, Parente RA, Szoka FC Jr.

Biochemistry. 1994 May 31;33(21):6721-31.

PMID:
8204607

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