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Items: 1 to 20 of 127

1.

A Stat5b transgene is capable of inducing CD8+ lymphoblastic lymphoma in the absence of normal TCR/MHC signaling.

Bessette K, Lang ML, Fava RA, Grundy M, Heinen J, Horne L, Spolski R, Al-Shami A, Morse HC 3rd, Leonard WJ, Kelly JA.

Blood. 2008 Jan 1;111(1):344-50. Epub 2007 Sep 21.

2.

Enhanced T cell lymphoma in NOD.Stat5b transgenic mice is caused by hyperactivation of Stat5b in CD8+ thymocytes.

Chen B, Yi B, Mao R, Liu H, Wang J, Sharma A, Peiper S, Leonard WJ, She JX.

PLoS One. 2013;8(2):e56600. doi: 10.1371/journal.pone.0056600. Epub 2013 Feb 14.

3.

The pre-TCR signal induces transcriptional silencing of the TCRγ locus by reducing the recruitment of STAT5 and Runx to transcriptional enhancers.

Tani-Ichi S, Satake M, Ikuta K.

Int Immunol. 2011 Sep;23(9):553-63. doi: 10.1093/intimm/dxr055. Epub 2011 Jul 12.

PMID:
21750145
4.

Stat5 synergizes with T cell receptor/antigen stimulation in the development of lymphoblastic lymphoma.

Kelly JA, Spolski R, Kovanen PE, Suzuki T, Bollenbacher J, Pise-Masison CA, Radonovich MF, Lee S, Jenkins NA, Copeland NG, Morse HC 3rd, Leonard WJ.

J Exp Med. 2003 Jul 7;198(1):79-89. Epub 2003 Jun 30.

5.

Lunatic Fringe prolongs Delta/Notch-induced self-renewal of committed αβ T-cell progenitors.

Yuan JS, Tan JB, Visan I, Matei IR, Urbanellis P, Xu K, Danska JS, Egan SE, Guidos CJ.

Blood. 2011 Jan 27;117(4):1184-95. doi: 10.1182/blood-2010-07-296616. Epub 2010 Nov 19.

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Critical Role of STAT5 transcription factor tetramerization for cytokine responses and normal immune function.

Lin JX, Li P, Liu D, Jin HT, He J, Ata Ur Rasheed M, Rochman Y, Wang L, Cui K, Liu C, Kelsall BL, Ahmed R, Leonard WJ.

Immunity. 2012 Apr 20;36(4):586-99. doi: 10.1016/j.immuni.2012.02.017.

10.

Role of thymic selection in the development of thymic lymphomas in TCR transgenic mice.

Strzadala L, Miazek A, Matuszyk J, Kisielow P.

Int Immunol. 1997 Jan;9(1):127-38.

PMID:
9043954
11.

Phenotypic and functional analysis of positive selection in the gamma/delta T cell lineage.

Wells FB, Tatsumi Y, Bluestone JA, Hedrick SM, Allison JP, Matis LA.

J Exp Med. 1993 Apr 1;177(4):1061-70.

12.

Constitutive activation of STAT5 supersedes the requirement for cytokine and TCR engagement of CD4+ T cells in steady-state homeostasis.

Taylor DK, Walsh PT, LaRosa DF, Zhang J, Burchill MA, Farrar MA, Turka LA.

J Immunol. 2006 Aug 15;177(4):2216-23.

13.

MHC-restricted T cell receptor signaling is required for alpha beta TCR replacement of the pre T cell receptor.

Croxford AL, Akilli-Ozturk O, Rieux-Laucat F, Förster I, Waisman A, Buch T.

Eur J Immunol. 2008 Feb;38(2):391-9. doi: 10.1002/eji.200737054.

14.

Clarifying the role of Stat5 in lymphoid development and Abelson-induced transformation.

Hoelbl A, Kovacic B, Kerenyi MA, Simma O, Warsch W, Cui Y, Beug H, Hennighausen L, Moriggl R, Sexl V.

Blood. 2006 Jun 15;107(12):4898-906. Epub 2006 Feb 21.

15.

The interferon regulatory transcription factor IRF-1 controls positive and negative selection of CD8+ thymocytes.

Penninger JM, Sirard C, Mittrücker HW, Chidgey A, Kozieradzki I, Nghiem M, Hakem A, Kimura T, Timms E, Boyd R, Taniguchi T, Matsuyama T, Mak TW.

Immunity. 1997 Aug;7(2):243-54.

16.

Modeling T-cell acute lymphoblastic leukemia induced by the SCL and LMO1 oncogenes.

Tremblay M, Tremblay CS, Herblot S, Aplan PD, Hébert J, Perreault C, Hoang T.

Genes Dev. 2010 Jun 1;24(11):1093-105. doi: 10.1101/gad.1897910.

17.

Examination of thymic positive and negative selection by flow cytometry.

Hu Q, Nicol SA, Suen AY, Baldwin TA.

J Vis Exp. 2012 Oct 8;(68). pii: 4269. doi: 10.3791/4269.

18.

Deregulated expression of RasGRP1 initiates thymic lymphomagenesis independently of T-cell receptors.

Klinger MB, Guilbault B, Goulding RE, Kay RJ.

Oncogene. 2005 Apr 14;24(16):2695-704.

PMID:
15829980
19.

The quantity of TCR signal determines positive selection and lineage commitment of T cells.

Watanabe N, Arase H, Onodera M, Ohashi PS, Saito T.

J Immunol. 2000 Dec 1;165(11):6252-61.

20.

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