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Items: 1 to 20 of 145


Heat shock factor 1 is a powerful multifaceted modifier of carcinogenesis.

Dai C, Whitesell L, Rogers AB, Lindquist S.

Cell. 2007 Sep 21;130(6):1005-18.


Non-oncogene addiction and the stress phenotype of cancer cells.

Solimini NL, Luo J, Elledge SJ.

Cell. 2007 Sep 21;130(6):986-8.


Defective heat shock factor 1 inhibits the growth of fibrosarcoma derived from simian virus 40/T antigen‑transformed MEF cells.

Jiang Q, Zhang Z, Li S, Wang Z, Ma Y, Hu Y.

Mol Med Rep. 2015 Nov;12(5):6517-26. doi: 10.3892/mmr.2015.4300. Epub 2015 Sep 9.


Loss of tumor suppressor NF1 activates HSF1 to promote carcinogenesis.

Dai C, Santagata S, Tang Z, Shi J, Cao J, Kwon H, Bronson RT, Whitesell L, Lindquist S.

J Clin Invest. 2012 Oct;122(10):3742-54. doi: 10.1172/JCI62727. Epub 2012 Sep 4.


Forkhead box M1 is regulated by heat shock factor 1 and promotes glioma cells survival under heat shock stress.

Dai B, Gong A, Jing Z, Aldape KD, Kang SH, Sawaya R, Huang S.

J Biol Chem. 2013 Jan 18;288(3):1634-42. doi: 10.1074/jbc.M112.379362. Epub 2012 Nov 28.


Deregulated minichromosomal maintenance protein MCM7 contributes to oncogene driven tumorigenesis.

Honeycutt KA, Chen Z, Koster MI, Miers M, Nuchtern J, Hicks J, Roop DR, Shohet JM.

Oncogene. 2006 Jul 6;25(29):4027-32. Epub 2006 Mar 6.


Early growth response 1 acts as a tumor suppressor in vivo and in vitro via regulation of p53.

Krones-Herzig A, Mittal S, Yule K, Liang H, English C, Urcis R, Soni T, Adamson ED, Mercola D.

Cancer Res. 2005 Jun 15;65(12):5133-43.


Heat-shock factor 1 both positively and negatively affects cellular clonogenic growth depending on p53 status.

Nguyen CH, Lang BJ, Chai RC, Vieusseux JL, Kouspou MM, Price JT.

Biochem J. 2013 Jun 1;452(2):321-9. doi: 10.1042/BJ20130098.


Heat shock transcription factor Hsf1 is involved in tumor progression via regulation of hypoxia-inducible factor 1 and RNA-binding protein HuR.

Gabai VL, Meng L, Kim G, Mills TA, Benjamin IJ, Sherman MY.

Mol Cell Biol. 2012 Mar;32(5):929-40. doi: 10.1128/MCB.05921-11. Epub 2012 Jan 3.


Interactions between wild-type and mutant Ras genes in lung and skin carcinogenesis.

To MD, Rosario RD, Westcott PM, Banta KL, Balmain A.

Oncogene. 2013 Aug 22;32(34):4028-33. doi: 10.1038/onc.2012.404. Epub 2012 Sep 3.


CCAAT/enhancer binding protein-beta is a mediator of keratinocyte survival and skin tumorigenesis involving oncogenic Ras signaling.

Zhu S, Yoon K, Sterneck E, Johnson PF, Smart RC.

Proc Natl Acad Sci U S A. 2002 Jan 8;99(1):207-12. Epub 2001 Dec 26.


PRAK is essential for ras-induced senescence and tumor suppression.

Sun P, Yoshizuka N, New L, Moser BA, Li Y, Liao R, Xie C, Chen J, Deng Q, Yamout M, Dong MQ, Frangou CG, Yates JR 3rd, Wright PE, Han J.

Cell. 2007 Jan 26;128(2):295-308.


DDB2 gene disruption leads to skin tumors and resistance to apoptosis after exposure to ultraviolet light but not a chemical carcinogen.

Itoh T, Cado D, Kamide R, Linn S.

Proc Natl Acad Sci U S A. 2004 Feb 17;101(7):2052-7. Epub 2004 Feb 9.


Heat shock factor 1-mediated aneuploidy requires a defective function of p53.

Kim EH, Lee YJ, Bae S, Lee JS, Kim J, Lee YS.

Cancer Res. 2009 Dec 15;69(24):9404-12. doi: 10.1158/0008-5472.CAN-09-1411. Epub .


Inactivating E2f1 reverts apoptosis resistance and cancer sensitivity in Trp53-deficient mice.

Wikonkal NM, Remenyik E, Knezevic D, Zhang W, Liu M, Zhao H, Berton TR, Johnson DG, Brash DE.

Nat Cell Biol. 2003 Jul;5(7):655-60.


Crucial role of phospholipase Cepsilon in chemical carcinogen-induced skin tumor development.

Bai Y, Edamatsu H, Maeda S, Saito H, Suzuki N, Satoh T, Kataoka T.

Cancer Res. 2004 Dec 15;64(24):8808-10.


Ras mutation promotes p53 activation and apoptosis of skin keratinocytes.

Zhao Y, Chaiswing L, Bakthavatchalu V, Oberley TD, St Clair DK.

Carcinogenesis. 2006 Aug;27(8):1692-8. Epub 2006 Apr 12.


An inducible mouse model for skin cancer reveals distinct roles for gain- and loss-of-function p53 mutations.

Caulin C, Nguyen T, Lang GA, Goepfert TM, Brinkley BR, Cai WW, Lozano G, Roop DR.

J Clin Invest. 2007 Jul;117(7):1893-901.


Dynamic regulation and involvement of the heat shock transcriptional response in arsenic carcinogenesis.

Khalil S, Luciano J, Chen W, Liu AY.

J Cell Physiol. 2006 May;207(2):562-9.

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