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Items: 1 to 20 of 104

1.

TLR9 activation induces normal neutrophil responses in a child with IRAK-4 deficiency: involvement of the direct PI3K pathway.

Hoarau C, Gérard B, Lescanne E, Henry D, François S, Lacapère JJ, El Benna J, Dang PM, Grandchamp B, Lebranchu Y, Gougerot-Pocidalo MA, Elbim C.

J Immunol. 2007 Oct 1;179(7):4754-65.

3.

Interleukin receptor-associated kinase-4 deficiency impairs Toll-like receptor-dependent innate antiviral immune responses.

McDonald DR, Brown D, Bonilla FA, Geha RS.

J Allergy Clin Immunol. 2006 Dec;118(6):1357-62. Epub 2006 Sep 25.

PMID:
17157666
4.

Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-{alpha} induction.

Uematsu S, Sato S, Yamamoto M, Hirotani T, Kato H, Takeshita F, Matsuda M, Coban C, Ishii KJ, Kawai T, Takeuchi O, Akira S.

J Exp Med. 2005 Mar 21;201(6):915-23. Epub 2005 Mar 14.

5.

Toll-like receptor responses in IRAK-4-deficient neutrophils.

van Bruggen R, Drewniak A, Tool AT, Jansen M, van Houdt M, Geissler J, van den Berg TK, Chapel H, Kuijpers TW.

J Innate Immun. 2010;2(3):280-7. doi: 10.1159/000268288. Epub 2009 Dec 16.

PMID:
20375545
6.

Pyogenic bacterial infections in humans with IRAK-4 deficiency.

Picard C, Puel A, Bonnet M, Ku CL, Bustamante J, Yang K, Soudais C, Dupuis S, Feinberg J, Fieschi C, Elbim C, Hitchcock R, Lammas D, Davies G, Al-Ghonaium A, Al-Rayes H, Al-Jumaah S, Al-Hajjar S, Al-Mohsen IZ, Frayha HH, Rucker R, Hawn TR, Aderem A, Tufenkeji H, Haraguchi S, Day NK, Good RA, Gougerot-Pocidalo MA, Ozinsky A, Casanova JL.

Science. 2003 Mar 28;299(5615):2076-9. Epub 2003 Mar 13.

7.

Toll-like receptor TLR2 and TLR9 ligation triggers neutrophil activation in granulomatosis with polyangiitis.

Holle JU, Windmöller M, Lange C, Gross WL, Herlyn K, Csernok E.

Rheumatology (Oxford). 2013 Jul;52(7):1183-9. doi: 10.1093/rheumatology/kes415. Epub 2013 Feb 12.

PMID:
23407387
8.

Activation of TLR-9 induces IL-8 secretion through peroxynitrite signaling in human neutrophils.

József L, Khreiss T, El Kebir D, Filep JG.

J Immunol. 2006 Jan 15;176(2):1195-202.

9.

IRAK-4 kinase activity is required for interleukin-1 (IL-1) receptor- and toll-like receptor 7-mediated signaling and gene expression.

Koziczak-Holbro M, Joyce C, Glück A, Kinzel B, Müller M, Tschopp C, Mathison JC, Davis CN, Gram H.

J Biol Chem. 2007 May 4;282(18):13552-60. Epub 2007 Mar 2.

10.

IRAK-M is a negative regulator of Toll-like receptor signaling.

Kobayashi K, Hernandez LD, Galán JE, Janeway CA Jr, Medzhitov R, Flavell RA.

Cell. 2002 Jul 26;110(2):191-202.

11.

Selective predisposition to bacterial infections in IRAK-4-deficient children: IRAK-4-dependent TLRs are otherwise redundant in protective immunity.

Ku CL, von Bernuth H, Picard C, Zhang SY, Chang HH, Yang K, Chrabieh M, Issekutz AC, Cunningham CK, Gallin J, Holland SM, Roifman C, Ehl S, Smart J, Tang M, Barrat FJ, Levy O, McDonald D, Day-Good NK, Miller R, Takada H, Hara T, Al-Hajjar S, Al-Ghonaium A, Speert D, Sanlaville D, Li X, Geissmann F, Vivier E, Maródi L, Garty BZ, Chapel H, Rodriguez-Gallego C, Bossuyt X, Abel L, Puel A, Casanova JL.

J Exp Med. 2007 Oct 1;204(10):2407-22. Epub 2007 Sep 24.

12.

TLR2- and TLR4-mediated signals determine attenuation or augmentation of inflammation by acute alcohol in monocytes.

Oak S, Mandrekar P, Catalano D, Kodys K, Szabo G.

J Immunol. 2006 Jun 15;176(12):7628-35.

13.
15.

A central role for the Hsp90.Cdc37 molecular chaperone module in interleukin-1 receptor-associated-kinase-dependent signaling by toll-like receptors.

De Nardo D, Masendycz P, Ho S, Cross M, Fleetwood AJ, Reynolds EC, Hamilton JA, Scholz GM.

J Biol Chem. 2005 Mar 18;280(11):9813-22. Epub 2005 Jan 12.

16.

Toll-like receptors stimulate human neutrophil function.

Hayashi F, Means TK, Luster AD.

Blood. 2003 Oct 1;102(7):2660-9. Epub 2003 Jun 26.

17.

Expression and function of Toll-like receptors in eosinophils: activation by Toll-like receptor 7 ligand.

Nagase H, Okugawa S, Ota Y, Yamaguchi M, Tomizawa H, Matsushima K, Ohta K, Yamamoto K, Hirai K.

J Immunol. 2003 Oct 15;171(8):3977-82.

18.

Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4.

Suzuki N, Suzuki S, Duncan GS, Millar DG, Wada T, Mirtsos C, Takada H, Wakeham A, Itie A, Li S, Penninger JM, Wesche H, Ohashi PS, Mak TW, Yeh WC.

Nature. 2002 Apr 18;416(6882):750-6. Epub 2002 Mar 31.

PMID:
11923871
19.

Interleukin-1 receptor-associated kinase 2- and protein kinase D1-dependent regulation of IRAK-monocyte expression by CpG DNA.

Kim YI, Park JE, Kwon KH, Hong CY, Yi AK.

PLoS One. 2012;7(8):e43970. doi: 10.1371/journal.pone.0043970. Epub 2012 Aug 23.

20.

IRAK4 kinase activity is redundant for interleukin-1 (IL-1) receptor-associated kinase phosphorylation and IL-1 responsiveness.

Qin J, Jiang Z, Qian Y, Casanova JL, Li X.

J Biol Chem. 2004 Jun 18;279(25):26748-53. Epub 2004 Apr 14.

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