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Items: 1 to 20 of 117

1.

Cadherin 23 and protocadherin 15 interact to form tip-link filaments in sensory hair cells.

Kazmierczak P, Sakaguchi H, Tokita J, Wilson-Kubalek EM, Milligan RA, Müller U, Kachar B.

Nature. 2007 Sep 6;449(7158):87-91.

PMID:
17805295
2.

Tip links in hair cells: molecular composition and role in hearing loss.

Sakaguchi H, Tokita J, Müller U, Kachar B.

Curr Opin Otolaryngol Head Neck Surg. 2009 Oct;17(5):388-93. doi: 10.1097/MOO.0b013e3283303472. Review.

3.

Development and regeneration of sensory transduction in auditory hair cells requires functional interaction between cadherin-23 and protocadherin-15.

Lelli A, Kazmierczak P, Kawashima Y, Müller U, Holt JR.

J Neurosci. 2010 Aug 25;30(34):11259-69. doi: 10.1523/JNEUROSCI.1949-10.2010.

4.

Noddy, a mouse harboring a missense mutation in protocadherin-15, reveals the impact of disrupting a critical interaction site between tip-link cadherins in inner ear hair cells.

Geng R, Sotomayor M, Kinder KJ, Gopal SR, Gerka-Stuyt J, Chen DH, Hardisty-Hughes RE, Ball G, Parker A, Gaudet R, Furness D, Brown SD, Corey DP, Alagramam KN.

J Neurosci. 2013 Mar 6;33(10):4395-404. doi: 10.1523/JNEUROSCI.4514-12.2013.

5.

Cadherin 23 is a component of the tip link in hair-cell stereocilia.

Siemens J, Lillo C, Dumont RA, Reynolds A, Williams DS, Gillespie PG, Müller U.

Nature. 2004 Apr 29;428(6986):950-5. Epub 2004 Mar 31.

6.

The CD2 isoform of protocadherin-15 is an essential component of the tip-link complex in mature auditory hair cells.

Pepermans E, Michel V, Goodyear R, Bonnet C, Abdi S, Dupont T, Gherbi S, Holder M, Makrelouf M, Hardelin JP, Marlin S, Zenati A, Richardson G, Avan P, Bahloul A, Petit C.

EMBO Mol Med. 2014 Jul;6(7):984-92. doi: 10.15252/emmm.201403976.

7.

Mutations in protocadherin 15 and cadherin 23 affect tip links and mechanotransduction in mammalian sensory hair cells.

Alagramam KN, Goodyear RJ, Geng R, Furness DN, van Aken AF, Marcotti W, Kros CJ, Richardson GP.

PLoS One. 2011 Apr 21;6(4):e19183. doi: 10.1371/journal.pone.0019183.

8.

Molecular remodeling of tip links underlies mechanosensory regeneration in auditory hair cells.

Indzhykulian AA, Stepanyan R, Nelina A, Spinelli KJ, Ahmed ZM, Belyantseva IA, Friedman TB, Barr-Gillespie PG, Frolenkov GI.

PLoS Biol. 2013;11(6):e1001583. doi: 10.1371/journal.pbio.1001583. Epub 2013 Jun 11.

9.

Cadherins and mechanotransduction by hair cells.

Müller U.

Curr Opin Cell Biol. 2008 Oct;20(5):557-66. doi: 10.1016/j.ceb.2008.06.004. Epub 2008 Jul 30. Review.

10.

Regulation of PCDH15 function in mechanosensory hair cells by alternative splicing of the cytoplasmic domain.

Webb SW, Grillet N, Andrade LR, Xiong W, Swarthout L, Della Santina CC, Kachar B, Müller U.

Development. 2011 Apr;138(8):1607-17. doi: 10.1242/dev.060061.

11.

Mutations in cadherin 23 affect tip links in zebrafish sensory hair cells.

Söllner C, Rauch GJ, Siemens J, Geisler R, Schuster SC, Müller U, Nicolson T; Tübingen 2000 Screen Consortium..

Nature. 2004 Apr 29;428(6986):955-9. Epub 2004 Mar 31.

12.

Structure of a force-conveying cadherin bond essential for inner-ear mechanotransduction.

Sotomayor M, Weihofen WA, Gaudet R, Corey DP.

Nature. 2012 Dec 6;492(7427):128-32. doi: 10.1038/nature11590. Epub 2012 Nov 7.

13.

The composition and role of cross links in mechanoelectrical transduction in vertebrate sensory hair cells.

Hackney CM, Furness DN.

J Cell Sci. 2013 Apr 15;126(Pt 8):1721-31. doi: 10.1242/jcs.106120. Epub 2013 May 2.

14.

The tip-link molecular complex of the auditory mechano-electrical transduction machinery.

Pepermans E, Petit C.

Hear Res. 2015 Dec;330(Pt A):10-7. doi: 10.1016/j.heares.2015.05.005. Epub 2015 Jun 3. Review.

PMID:
26049141
15.

The dimensions and structural attachments of tip links in mammalian cochlear hair cells and the effects of exposure to different levels of extracellular calcium.

Furness DN, Katori Y, Nirmal Kumar B, Hackney CM.

Neuroscience. 2008 Jun 12;154(1):10-21. doi: 10.1016/j.neuroscience.2008.02.010. Epub 2008 Feb 19.

PMID:
18384968
16.

Hair cells, plasma membrane Ca²⁺ ATPase and deafness.

Giacomello M, De Mario A, Primerano S, Brini M, Carafoli E.

Int J Biochem Cell Biol. 2012 May;44(5):679-83. doi: 10.1016/j.biocel.2012.02.006. Epub 2012 Feb 13. Review.

PMID:
22349217
17.

The tip-link antigen, a protein associated with the transduction complex of sensory hair cells, is protocadherin-15.

Ahmed ZM, Goodyear R, Riazuddin S, Lagziel A, Legan PK, Behra M, Burgess SM, Lilley KS, Wilcox ER, Riazuddin S, Griffith AJ, Frolenkov GI, Belyantseva IA, Richardson GP, Friedman TB.

J Neurosci. 2006 Jun 28;26(26):7022-34.

18.

Asymmetric distribution of cadherin 23 and protocadherin 15 in the kinocilial links of avian sensory hair cells.

Goodyear RJ, Forge A, Legan PK, Richardson GP.

J Comp Neurol. 2010 Nov 1;518(21):4288-97. doi: 10.1002/cne.22456.

19.

A core cochlear phenotype in USH1 mouse mutants implicates fibrous links of the hair bundle in its cohesion, orientation and differential growth.

Lefèvre G, Michel V, Weil D, Lepelletier L, Bizard E, Wolfrum U, Hardelin JP, Petit C.

Development. 2008 Apr;135(8):1427-37. doi: 10.1242/dev.012922. Epub 2008 Mar 13.

20.

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