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Sodium and chloride absorptive defects in the small intestine in Slc26a6 null mice.

Seidler U, Rottinghaus I, Hillesheim J, Chen M, Riederer B, Krabbenhöft A, Engelhardt R, Wiemann M, Wang Z, Barone S, Manns MP, Soleimani M.

Pflugers Arch. 2008 Jan;455(4):757-66. Epub 2007 Sep 1.


Intestinal NaCl transport in NHE2 and NHE3 knockout mice.

Gawenis LR, Stien X, Shull GE, Schultheis PJ, Woo AL, Walker NM, Clarke LL.

Am J Physiol Gastrointest Liver Physiol. 2002 May;282(5):G776-84.


Electroneutral sodium absorption and electrogenic anion secretion across murine small intestine are regulated in parallel.

Gawenis LR, Hut H, Bot AG, Shull GE, de Jonge HR, Stien X, Miller ML, Clarke LL.

Am J Physiol Gastrointest Liver Physiol. 2004 Dec;287(6):G1140-9. Epub 2004 Jul 29.


Segregation of Na/H exchanger-3 and Cl/HCO3 exchanger SLC26A3 (DRA) in rodent cecum and colon.

Talbot C, Lytle C.

Am J Physiol Gastrointest Liver Physiol. 2010 Aug;299(2):G358-67. doi: 10.1152/ajpgi.00151.2010. Epub 2010 May 13.


Mechanisms of diarrhea in the interleukin-2-deficient mouse model of colonic inflammation.

Barmeyer C, Harren M, Schmitz H, Heinzel-Pleines U, Mankertz J, Seidler U, Horak I, Wiedenmann B, Fromm M, Schulzke JD.

Am J Physiol Gastrointest Liver Physiol. 2004 Feb;286(2):G244-52.


Down regulation of small intestinal ion transport in PDZK1- (CAP70/NHERF3) deficient mice.

Hillesheim J, Riederer B, Tuo B, Chen M, Manns M, Biber J, Yun C, Kocher O, Seidler U.

Pflugers Arch. 2007 Jul;454(4):575-86. Epub 2007 Mar 9.


Preserved Na(+)/H(+) exchanger isoform 3 expression and localization, but decreased NHE3 function indicate regulatory sodium transport defect in ulcerative colitis.

Yeruva S, Farkas K, Hubricht J, Rode K, Riederer B, Bachmann O, Cinar A, Rakonczay Z, Molnár T, Nagy F, Wedemeyer J, Manns M, Raddatz D, Musch MW, Chang EB, Hegyi P, Seidler U.

Inflamm Bowel Dis. 2010 Jul;16(7):1149-61. doi: 10.1002/ibd.21183.


Down-regulated in adenoma Cl/HCO3 exchanger couples with Na/H exchanger 3 for NaCl absorption in murine small intestine.

Walker NM, Simpson JE, Yen PF, Gill RK, Rigsby EV, Brazill JM, Dudeja PK, Schweinfest CW, Clarke LL.

Gastroenterology. 2008 Nov;135(5):1645-1653.e3. doi: 10.1053/j.gastro.2008.07.083. Epub 2008 Aug 7.


Renal and intestinal absorptive defects in mice lacking the NHE3 Na+/H+ exchanger.

Schultheis PJ, Clarke LL, Meneton P, Miller ML, Soleimani M, Gawenis LR, Riddle TM, Duffy JJ, Doetschman T, Wang T, Giebisch G, Aronson PS, Lorenz JN, Shull GE.

Nat Genet. 1998 Jul;19(3):282-5.


Brush border phosphatidylinositol 3-kinase mediates epidermal growth factor stimulation of intestinal NaCl absorption and Na+/H+ exchange.

Khurana S, Nath SK, Levine SA, Bowser JM, Tse CM, Cohen ME, Donowitz M.

J Biol Chem. 1996 Apr 26;271(17):9919-27.


PAT-1 (Slc26a6) is the predominant apical membrane Cl-/HCO3- exchanger in the upper villous epithelium of the murine duodenum.

Simpson JE, Schweinfest CW, Shull GE, Gawenis LR, Walker NM, Boyle KT, Soleimani M, Clarke LL.

Am J Physiol Gastrointest Liver Physiol. 2007 Apr;292(4):G1079-88. Epub 2006 Dec 14.


The Na+/H+ exchange isoform NHE3 regulates basal canine ileal Na+ absorption in vivo.

Maher MM, Gontarek JD, Bess RS, Donowitz M, Yeo CJ.

Gastroenterology. 1997 Jan;112(1):174-83.


Identification of an apical Cl-/HCO-3 exchanger in rat kidney proximal tubule.

Petrovic S, Ma L, Wang Z, Soleimani M.

Am J Physiol Cell Physiol. 2003 Sep;285(3):C608-17. Epub 2003 May 7.


Dietary fructose, salt absorption and hypertension in metabolic syndrome: towards a new paradigm.

Soleimani M.

Acta Physiol (Oxf). 2011 Jan;201(1):55-62. doi: 10.1111/j.1748-1716.2010.02167.x. Review.


cAMP inhibition of murine intestinal Na/H exchange requires CFTR-mediated cell shrinkage of villus epithelium.

Gawenis LR, Franklin CL, Simpson JE, Palmer BA, Walker NM, Wiggins TM, Clarke LL.

Gastroenterology. 2003 Oct;125(4):1148-63.


Slc26a6 (PAT1) deletion downregulates the apical Na+/H+ exchanger in the straight segment of the proximal tubule.

Petrovic S, Barone S, Wang Z, McDonough AA, Amlal H, Soleimani M.

Am J Nephrol. 2008;28(2):330-8. Epub 2007 Nov 29.


D-glucose acts via sodium/glucose cotransporter 1 to increase NHE3 in mouse jejunal brush border by a Na+/H+ exchange regulatory factor 2-dependent process.

Lin R, Murtazina R, Cha B, Chakraborty M, Sarker R, Chen TE, Lin Z, Hogema BM, de Jonge HR, Seidler U, Turner JR, Li X, Kovbasnjuk O, Donowitz M.

Gastroenterology. 2011 Feb;140(2):560-71. doi: 10.1053/j.gastro.2010.10.042. Epub 2010 Oct 23.


Influence of ammonia on sodium absorption in rat proximal colon.

Cermak R, Lawnitzak C, Scharrer E.

Pflugers Arch. 2000 Aug;440(4):619-26.


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