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Items: 1 to 20 of 163

1.

Replication protein A is required for etoposide-induced assembly of MRE11/RAD50/NBS1 complex repair foci.

Robison JG, Bissler JJ, Dixon K.

Cell Cycle. 2007 Oct 1;6(19):2408-16. Epub 2007 Jul 20.

PMID:
17700070
2.
3.

DNA lesion-specific co-localization of the Mre11/Rad50/Nbs1 (MRN) complex and replication protein A (RPA) to repair foci.

Robison JG, Lu L, Dixon K, Bissler JJ.

J Biol Chem. 2005 Apr 1;280(13):12927-34. Epub 2005 Jan 14.

4.

Replication protein A and the Mre11.Rad50.Nbs1 complex co-localize and interact at sites of stalled replication forks.

Robison JG, Elliott J, Dixon K, Oakley GG.

J Biol Chem. 2004 Aug 13;279(33):34802-10. Epub 2004 Jun 4.

5.

The Mre11/Rad50/Nbs1 complex plays an important role in the prevention of DNA rereplication in mammalian cells.

Lee AY, Liu E, Wu X.

J Biol Chem. 2007 Nov 2;282(44):32243-55. Epub 2007 Aug 22.

6.
7.

Physical interaction between replication protein A (RPA) and MRN: involvement of RPA2 phosphorylation and the N-terminus of RPA1.

Oakley GG, Tillison K, Opiyo SA, Glanzer JG, Horn JM, Patrick SM.

Biochemistry. 2009 Aug 11;48(31):7473-81. doi: 10.1021/bi900694p.

8.

Defective Mre11-dependent activation of Chk2 by ataxia telangiectasia mutated in colorectal carcinoma cells in response to replication-dependent DNA double strand breaks.

Takemura H, Rao VA, Sordet O, Furuta T, Miao ZH, Meng L, Zhang H, Pommier Y.

J Biol Chem. 2006 Oct 13;281(41):30814-23. Epub 2006 Aug 10.

9.

ATM and the Mre11-Rad50-Nbs1 complex respond to nucleoside analogue-induced stalled replication forks and contribute to drug resistance.

Ewald B, Sampath D, Plunkett W.

Cancer Res. 2008 Oct 1;68(19):7947-55. doi: 10.1158/0008-5472.CAN-08-0971.

11.

Rad17 recruits the MRE11-RAD50-NBS1 complex to regulate the cellular response to DNA double-strand breaks.

Wang Q, Goldstein M, Alexander P, Wakeman TP, Sun T, Feng J, Lou Z, Kastan MB, Wang XF.

EMBO J. 2014 Apr 16;33(8):862-77. doi: 10.1002/embj.201386064. Epub 2014 Feb 16.

12.

MCM8-9 complex promotes resection of double-strand break ends by MRE11-RAD50-NBS1 complex.

Lee KY, Im JS, Shibata E, Park J, Handa N, Kowalczykowski SC, Dutta A.

Nat Commun. 2015 Jul 28;6:7744. doi: 10.1038/ncomms8744.

13.

Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template.

Williams RS, Williams JS, Tainer JA.

Biochem Cell Biol. 2007 Aug;85(4):509-20. Review.

PMID:
17713585
14.

Smad7 enhances ATM activity by facilitating the interaction between ATM and Mre11-Rad50-Nbs1 complex in DNA double-strand break repair.

Park S, Kang JM, Kim SJ, Kim H, Hong S, Lee YJ, Kim SJ.

Cell Mol Life Sci. 2015 Feb;72(3):583-96. doi: 10.1007/s00018-014-1687-z. Epub 2014 Jul 26.

PMID:
25063542
15.

The Mre11/Rad50/Nbs1 complex and its role as a DNA double-strand break sensor for ATM.

Paull TT, Lee JH.

Cell Cycle. 2005 Jun;4(6):737-40. Epub 2005 Jun 6.

PMID:
15908798
16.
17.

MRE11-RAD50-NBS1 complex dictates DNA repair independent of H2AX.

Yuan J, Chen J.

J Biol Chem. 2010 Jan 8;285(2):1097-104. doi: 10.1074/jbc.M109.078436. Epub 2009 Nov 12.

18.

Transcription-coupled DNA double-strand breaks are mediated via the nucleotide excision repair and the Mre11-Rad50-Nbs1 complex.

Guirouilh-Barbat J, Redon C, Pommier Y.

Mol Biol Cell. 2008 Sep;19(9):3969-81. doi: 10.1091/mbc.E08-02-0215. Epub 2008 Jul 16.

19.

Productive replication of human papillomavirus 31 requires DNA repair factor Nbs1.

Anacker DC, Gautam D, Gillespie KA, Chappell WH, Moody CA.

J Virol. 2014 Aug;88(15):8528-44. doi: 10.1128/JVI.00517-14. Epub 2014 May 21.

20.

Physical interaction between the histone acetyl transferase Tip60 and the DNA double-strand breaks sensor MRN complex.

Chailleux C, Tyteca S, Papin C, Boudsocq F, Puget N, Courilleau C, Grigoriev M, Canitrot Y, Trouche D.

Biochem J. 2010 Feb 24;426(3):365-71. doi: 10.1042/BJ20091329.

PMID:
20070254

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