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Items: 1 to 20 of 170

1.

Central sympatholysis as a novel countermeasure for cocaine-induced sympathetic activation and vasoconstriction in humans.

Menon DV, Wang Z, Fadel PJ, Arbique D, Leonard D, Li JL, Victor RG, Vongpatanasin W.

J Am Coll Cardiol. 2007 Aug 14;50(7):626-33. Epub 2007 Jul 30.

2.

Cocaine stimulates the human cardiovascular system via a central mechanism of action.

Vongpatanasin W, Mansour Y, Chavoshan B, Arbique D, Victor RG.

Circulation. 1999 Aug 3;100(5):497-502.

3.

A novel alpha 2-adrenoceptor antagonist attenuates the early, but preserves the late cardiovascular effects of intravenous dexmedetomidine in conscious dogs.

Pagel PS, Proctor LT, Devcic A, Hettrick DA, Kersten JR, Tessmer JP, Farber NE, Schmeling WT, Warltier DC.

J Cardiothorac Vasc Anesth. 1998 Aug;12(4):429-34.

PMID:
9713732
4.

Effects of low and high plasma concentrations of dexmedetomidine on myocardial perfusion and cardiac function in healthy male subjects.

Snapir A, Posti J, Kentala E, Koskenvuo J, Sundell J, Tuunanen H, Hakala K, Scheinin H, Knuuti J, Scheinin M.

Anesthesiology. 2006 Nov;105(5):902-10; quiz 1069-70.

PMID:
17065883
5.

Alpha-2B adrenoceptor polymorphism and peripheral vasoconstriction.

Talke P, Stapelfeldt C, Lobo E, Brown R, Scheinin M, Snapir A.

Pharmacogenet Genomics. 2005 May;15(5):357-63.

PMID:
15864138
6.

Mechanism of the blood pressure--raising effect of cocaine in humans.

Tuncel M, Wang Z, Arbique D, Fadel PJ, Victor RG, Vongpatanasin W.

Circulation. 2002 Mar 5;105(9):1054-9.

7.

Effect of alpha2B-adrenoceptor polymorphism on peripheral vasoconstriction in healthy volunteers.

Talke P, Stapelfeldt C, Lobo E, Brown R, Scheinin M, Snapir A.

Anesthesiology. 2005 Mar;102(3):536-42.

PMID:
15731590
8.

Dexmedetomidine as a novel countermeasure for cocaine-induced central sympathoexcitation in cocaine-addicted humans.

Kontak AC, Victor RG, Vongpatanasin W.

Hypertension. 2013 Feb;61(2):388-94. doi: 10.1161/HYPERTENSIONAHA.112.203554. Epub 2013 Jan 2.

9.

Cardiovascular reactivity to mental stress is not affected by alpha2-adrenoreceptor activation or inhibition.

Philippsen C, Hahn M, Schwabe L, Richter S, Drewe J, Schachinger H.

Psychopharmacology (Berl). 2007 Feb;190(2):181-8. Epub 2006 Nov 17.

PMID:
17111173
10.

The effects of esmolol and dexmedetomidine on myocardial oxygen consumption during sympathetic stimulation in dogs.

Willigers HM, Prinzen FW, Roekaerts PM.

J Cardiothorac Vasc Anesth. 2006 Jun;20(3):364-70. Epub 2006 Apr 5.

PMID:
16750737
11.

Alpha2B adrenergic receptor 301-303 deletion polymorphism and vascular alpha2 adrenergic receptor response.

Muszkat M, Sofowora GG, Xie HG, Wood AJ, Stein CM.

Pharmacogenet Genomics. 2005 Jan;15(1):23-8.

PMID:
15864122
12.

Systemically administered alpha2-agonist-induced peripheral vasoconstriction in humans.

Talke P, Lobo E, Brown R.

Anesthesiology. 2003 Jul;99(1):65-70.

PMID:
12826844
13.

Effect of the alpha2-agonist dexmedetomidine on cerebral neurotransmitter concentrations during cerebral ischemia in rats.

Engelhard K, Werner C, Kaspar S, Möllenberg O, Blobner M, Bachl M, Kochs E.

Anesthesiology. 2002 Feb;96(2):450-7.

PMID:
11818781
14.

Cocaine-induced cardiovascular effects: lack of evidence for a central nervous system site of action based on hemodynamic studies with cocaine methiodide.

Dickerson LW, Rodak DJ, Kuhn FE, Wahlstrom SK, Tessel RE, Visner MS, Schaer GL, Gillis RA.

J Cardiovasc Pharmacol. 1999 Jan;33(1):36-42.

PMID:
9890394
15.

Sympathoneural and adrenomedullary functional effects of alpha2C-adrenoreceptor gene polymorphism in healthy humans.

Neumeister A, Charney DS, Belfer I, Geraci M, Holmes C, Sharabi Y, Alim T, Bonne O, Luckenbaugh DA, Manji H, Goldman D, Goldstein DS.

Pharmacogenet Genomics. 2005 Mar;15(3):143-9.

PMID:
15861038
16.

Cocaine inhibits sympathetic neural activity by acting in the central nervous system and at the sympathetic ganglion.

Hernandez YM, Raczkowski VF, Dretchen KL, Gillis RA.

J Pharmacol Exp Ther. 1996 May;277(2):1114-21.

PMID:
8627523
17.

Effects of nitric oxide synthase inhibition on dexmedetomidine-induced vasoconstriction in healthy human volunteers.

Snapir A, Talke P, Posti J, Huiku M, Kentala E, Scheinin M.

Br J Anaesth. 2009 Jan;102(1):38-46. doi: 10.1093/bja/aen316. Epub 2008 Nov 5.

PMID:
18987056
18.

The central hypotensive effect induced by alpha 2-adrenergic receptor stimulation is dependent on endothelial nitric oxide synthase.

Feldman J, Fellmann L, Bousquet P.

J Hypertens. 2008 May;26(5):1033-6. doi: 10.1097/HJH.0b013e3282f7cbab.

PMID:
18398347
19.

Cocaine effects on digital blood flow and diffusing capacity for carbon monoxide among chronic cocaine users.

Sullivan JT, Becker PM, Preston KL, Wise RA, Wigely FM, Testa MP, Jasinski DR.

Am J Med. 1997 Mar;102(3):232-8.

PMID:
9217590
20.

The effects of increasing plasma concentrations of dexmedetomidine in humans.

Ebert TJ, Hall JE, Barney JA, Uhrich TD, Colinco MD.

Anesthesiology. 2000 Aug;93(2):382-94.

PMID:
10910487

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