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Items: 1 to 20 of 95

1.

The potential of high-content high-throughput microscopy in drug discovery.

Starkuviene V, Pepperkok R.

Br J Pharmacol. 2007 Sep;152(1):62-71. Epub 2007 Jul 2. Review.

2.
3.

Multidimensional drug profiling by automated microscopy.

Perlman ZE, Slack MD, Feng Y, Mitchison TJ, Wu LF, Altschuler SJ.

Science. 2004 Nov 12;306(5699):1194-8.

4.

Integrated expressional analysis: application to the drug discovery process.

Ilyin SE, Horowitz D, Belkowski SM, Xin H, Eckardt AJ, Darrow AL, Chen C, Maley D, D'Andrea M, Plata-Salamán CR, Derian CK.

Methods. 2005 Nov;37(3):280-8.

PMID:
16308157
5.

Image-based screening: a technology in transition.

Ramm P.

Curr Opin Biotechnol. 2005 Feb;16(1):41-8. Review.

PMID:
15722014
6.

Image-based chemical screening.

Carpenter AE.

Nat Chem Biol. 2007 Aug;3(8):461-5. Review.

PMID:
17637778
7.

Live cell imaging: an industrial perspective.

McCann T.

Methods Mol Biol. 2010;591:47-66. doi: 10.1007/978-1-60761-404-3_3.

PMID:
19957123
8.

Technological advances in high-throughput screening.

Liu B, Li S, Hu J.

Am J Pharmacogenomics. 2004;4(4):263-76. Review.

PMID:
15287820
9.

High-throughput RNAi screening by time-lapse imaging of live human cells.

Neumann B, Held M, Liebel U, Erfle H, Rogers P, Pepperkok R, Ellenberg J.

Nat Methods. 2006 May;3(5):385-90.

PMID:
16628209
10.

Label-free cytotoxicity screening assay by digital holographic microscopy.

Kühn J, Shaffer E, Mena J, Breton B, Parent J, Rappaz B, Chambon M, Emery Y, Magistretti P, Depeursinge C, Marquet P, Turcatti G.

Assay Drug Dev Technol. 2013 Mar;11(2):101-7. doi: 10.1089/adt.2012.476. Epub 2012 Oct 12.

11.

Automated image analysis for high-content screening and analysis.

Shariff A, Kangas J, Coelho LP, Quinn S, Murphy RF.

J Biomol Screen. 2010 Aug;15(7):726-34. doi: 10.1177/1087057110370894. Epub 2010 May 20. Review.

PMID:
20488979
12.

Cellular imaging in drug discovery.

Lang P, Yeow K, Nichols A, Scheer A.

Nat Rev Drug Discov. 2006 Apr;5(4):343-56. Review.

PMID:
16582878
13.

Quantitative in vivo microscopy: the return from the 'omics'.

Fernández-González R, Muñoz-Barrutia A, Barcellos-Hoff MH, Ortiz-de-Solorzano C.

Curr Opin Biotechnol. 2006 Oct;17(5):501-10. Epub 2006 Aug 8. Review.

PMID:
16899361
14.

Automated live microscopy to study mitotic gene function in fluorescent reporter cell lines.

Schmitz MH, Gerlich DW.

Methods Mol Biol. 2009;545:113-34. doi: 10.1007/978-1-60327-993-2_7.

PMID:
19475385
15.

Novel fluorescent proteins for high-content screening.

Wolff M, Wiedenmann J, Nienhaus GU, Valler M, Heilker R.

Drug Discov Today. 2006 Dec;11(23-24):1054-60. Epub 2006 Sep 25. Review.

PMID:
17129823
16.

High-content analysis in preclinical drug discovery.

Denner P, Schmalowsky J, Prechtl S.

Comb Chem High Throughput Screen. 2008 Mar;11(3):216-30. Review.

PMID:
18336214
17.

Improvement of the green fluorescent protein reporter system in Leishmania spp. for the in vitro and in vivo screening of antileishmanial drugs.

Pulido SA, Muñoz DL, Restrepo AM, Mesa CV, Alzate JF, Vélez ID, Robledo SM.

Acta Trop. 2012 Apr;122(1):36-45. doi: 10.1016/j.actatropica.2011.11.015. Epub 2011 Dec 6.

PMID:
22155571
18.

Fixation and paraffin-embedding of mouse tissues for GFP visualization.

Vankelecom H.

Cold Spring Harb Protoc. 2009 Oct;2009(10):pdb.prot5298. doi: 10.1101/pdb.prot5298.

PMID:
20147043
19.

Pluripotent human stem cells as novel tools in drug discovery and toxicity testing.

Sartipy P, Bjorquist P, Strehl R, Hyllner J.

IDrugs. 2006 Oct;9(10):702-5.

PMID:
17016777
20.

Image-based high-throughput screening for inhibitors of angiogenesis.

Evensen L, Link W, Lorens JB.

Methods Mol Biol. 2013;931:139-51. doi: 10.1007/978-1-62703-056-4_8.

PMID:
23027002

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