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Items: 1 to 20 of 299

1.

A role for LKB1 gene in human cancer beyond the Peutz-Jeghers syndrome.

Sanchez-Cespedes M.

Oncogene. 2007 Dec 13;26(57):7825-32. Review.

PMID:
17599048
2.

The molecular mechanisms that underlie the tumor suppressor function of LKB1.

Fan D, Ma C, Zhang H.

Acta Biochim Biophys Sin (Shanghai). 2009 Feb;41(2):97-107. Review.

3.

Low frequency of somatic mutations in the LKB1/Peutz-Jeghers syndrome gene in sporadic breast cancer.

Bignell GR, Barfoot R, Seal S, Collins N, Warren W, Stratton MR.

Cancer Res. 1998 Apr 1;58(7):1384-6.

4.

A novel germline mutation of the LKB1 gene in a patient with Peutz-Jeghers syndrome with early-onset gastric cancer.

Takahashi M, Sakayori M, Takahashi S, Kato T, Kaji M, Kawahara M, Suzuki T, Kato S, Kato S, Shibata H, Murakawa Y, Yoshioka T, Ishioka C.

J Gastroenterol. 2004 Dec;39(12):1210-4.

PMID:
15622488
5.

Distinctive gene expression of human lung adenocarcinomas carrying LKB1 mutations.

Fernandez P, Carretero J, Medina PP, Jimenez AI, Rodriguez-Perales S, Paz MF, Cigudosa JC, Esteller M, Lombardia L, Morente M, Sanchez-Verde L, Sotelo T, Sanchez-Cespedes M.

Oncogene. 2004 Jun 24;23(29):5084-91.

PMID:
15077168
6.

Novel and natural knockout lung cancer cell lines for the LKB1/STK11 tumor suppressor gene.

Carretero J, Medina PP, Pio R, Montuenga LM, Sanchez-Cespedes M.

Oncogene. 2004 May 13;23(22):4037-40.

PMID:
15021901
7.

STRAD in Peutz-Jeghers syndrome and sporadic cancers.

de Leng WW, Keller JJ, Luiten S, Musler AR, Jansen M, Baas AF, de Rooij FW, Gille JJ, Menko FH, Offerhaus GJ, Weterman MA.

J Clin Pathol. 2005 Oct;58(10):1091-5.

8.

Mutations and impaired function of LKB1 in familial and non-familial Peutz-Jeghers syndrome and a sporadic testicular cancer.

Ylikorkala A, Avizienyte E, Tomlinson IP, Tiainen M, Roth S, Loukola A, Hemminki A, Johansson M, Sistonen P, Markie D, Neale K, Phillips R, Zauber P, Twama T, Sampson J, Järvinen H, Mäkelä TP, Aaltonen LA.

Hum Mol Genet. 1999 Jan;8(1):45-51.

9.

No evidence of Peutz-Jeghers syndrome gene LKB1 involvement in left-sided colorectal carcinomas.

Launonen V, Avizienyte E, Loukola A, Laiho P, Salovaara R, Järvinen H, Mecklin JP, Oku A, Shimane M, Kim HC, Kim JC, Nezu J, Aaltonen LA.

Cancer Res. 2000 Feb 1;60(3):546-8.

10.

Allele loss and mutation screen at the Peutz-Jeghers (LKB1) locus (19p13.3) in sporadic ovarian tumours.

Wang ZJ, Churchman M, Campbell IG, Xu WH, Yan ZY, McCluggage WG, Foulkes WD, Tomlinson IP.

Br J Cancer. 1999 Apr;80(1-2):70-2.

11.
12.

Functional analysis of Peutz-Jeghers mutations reveals that the LKB1 C-terminal region exerts a crucial role in regulating both the AMPK pathway and the cell polarity.

Forcet C, Etienne-Manneville S, Gaude H, Fournier L, Debilly S, Salmi M, Baas A, Olschwang S, Clevers H, Billaud M.

Hum Mol Genet. 2005 May 15;14(10):1283-92.

13.

Mutations in the human LKB1/STK11 gene.

Launonen V.

Hum Mutat. 2005 Oct;26(4):291-7. Review.

PMID:
16110486
14.

Loss of LKB1 kinase activity in Peutz-Jeghers syndrome, and evidence for allelic and locus heterogeneity.

Mehenni H, Gehrig C, Nezu J, Oku A, Shimane M, Rossier C, Guex N, Blouin JL, Scott HS, Antonarakis SE.

Am J Hum Genet. 1998 Dec;63(6):1641-50.

15.

Somatic mutation of the Peutz-Jeghers syndrome gene, LKB1/STK11, in malignant melanoma.

Guldberg P, thor Straten P, Ahrenkiel V, Seremet T, Kirkin AF, Zeuthen J.

Oncogene. 1999 Mar 4;18(9):1777-80.

16.

The role of LKB1 in lung cancer.

Sanchez-Cespedes M.

Fam Cancer. 2011 Sep;10(3):447-53. doi: 10.1007/s10689-011-9443-0. Review.

PMID:
21516316
17.

LKB1 mutation in large cell carcinoma of the lung.

Zhong D, Guo L, de Aguirre I, Liu X, Lamb N, Sun SY, Gal AA, Vertino PM, Zhou W.

Lung Cancer. 2006 Sep;53(3):285-94.

PMID:
16822578
18.

Mutation analysis of the STK11/LKB1 gene and clinical characteristics of an Australian series of Peutz-Jeghers syndrome patients.

Scott RJ, Crooks R, Meldrum CJ, Thomas L, Smith CJ, Mowat D, McPhillips M, Spigelman AD.

Clin Genet. 2002 Oct;62(4):282-7.

PMID:
12372054
19.

Molecular and clinical characteristics in 46 families affected with Peutz-Jeghers syndrome.

Mehenni H, Resta N, Guanti G, Mota-Vieira L, Lerner A, Peyman M, Chong KA, Aissa L, Ince A, Cosme A, Costanza MC, Rossier C, Radhakrishna U, Burt RW, Picard D.

Dig Dis Sci. 2007 Aug;52(8):1924-33.

PMID:
17404884
20.

Epigenetic inactivation of LKB1 in primary tumors associated with the Peutz-Jeghers syndrome.

Esteller M, Avizienyte E, Corn PG, Lothe RA, Baylin SB, Aaltonen LA, Herman JG.

Oncogene. 2000 Jan 6;19(1):164-8.

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