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Items: 1 to 20 of 135

1.

Knockdown of astrocyte-elevated gene-1 inhibits prostate cancer progression through upregulation of FOXO3a activity.

Kikuno N, Shiina H, Urakami S, Kawamoto K, Hirata H, Tanaka Y, Place RF, Pookot D, Majid S, Igawa M, Dahiya R.

Oncogene. 2007 Dec 6;26(55):7647-55. Epub 2007 Jun 11.

PMID:
17563745
2.

Apigenin inhibits prostate cancer progression in TRAMP mice via targeting PI3K/Akt/FoxO pathway.

Shukla S, Bhaskaran N, Babcook MA, Fu P, Maclennan GT, Gupta S.

Carcinogenesis. 2014 Feb;35(2):452-60. doi: 10.1093/carcin/bgt316. Epub 2013 Sep 25.

3.

NSC126188 induces apoptosis of prostate cancer PC-3 cells through inhibition of Akt membrane translocation, FoxO3a activation, and RhoB transcription.

Won KJ, Kim BK, Han G, Lee K, Jung YJ, Kim HM, Song KB, Chung KS, Won M.

Apoptosis. 2014 Jan;19(1):179-90. doi: 10.1007/s10495-013-0905-8.

PMID:
24085402
4.

Deregulation of FOXO3A during prostate cancer progression.

Shukla S, Shukla M, Maclennan GT, Fu P, Gupta S.

Int J Oncol. 2009 Jun;34(6):1613-20.

5.

Activation of the nuclear factor kappaB pathway by astrocyte elevated gene-1: implications for tumor progression and metastasis.

Emdad L, Sarkar D, Su ZZ, Randolph A, Boukerche H, Valerie K, Fisher PB.

Cancer Res. 2006 Feb 1;66(3):1509-16.

6.

Estrogen receptor β upregulates FOXO3a and causes induction of apoptosis through PUMA in prostate cancer.

Dey P, Ström A, Gustafsson JÅ.

Oncogene. 2014 Aug 14;33(33):4213-25. doi: 10.1038/onc.2013.384. Epub 2013 Sep 30.

PMID:
24077289
7.

Astrocyte elevated gene-1 is a proliferation promoter in breast cancer via suppressing transcriptional factor FOXO1.

Li J, Yang L, Song L, Xiong H, Wang L, Yan X, Yuan J, Wu J, Li M.

Oncogene. 2009 Sep 10;28(36):3188-96. doi: 10.1038/onc.2009.171. Epub 2009 Jul 27.

PMID:
19633686
8.

Curcumin downregulates cell survival mechanisms in human prostate cancer cell lines.

Mukhopadhyay A, Bueso-Ramos C, Chatterjee D, Pantazis P, Aggarwal BB.

Oncogene. 2001 Nov 15;20(52):7597-609.

10.

Antitumor effects of the novel quinazolinone MJ-33: inhibition of metastasis through the MAPK, AKT, NF-κB and AP-1 signaling pathways in DU145 human prostate cancer cells.

Hour MJ, Tsai SC, Wu HC, Lin MW, Chung JG, Wu JB, Chiang JH, Tsuzuki M, Yang JS.

Int J Oncol. 2012 Oct;41(4):1513-9. doi: 10.3892/ijo.2012.1560. Epub 2012 Jul 18.

PMID:
22825655
11.

Inhibition of AKT promotes FOXO3a-dependent apoptosis in prostate cancer.

Das TP, Suman S, Alatassi H, Ankem MK, Damodaran C.

Cell Death Dis. 2016 Feb 25;7:e2111. doi: 10.1038/cddis.2015.403.

12.

Astrocyte elevated gene-1 promotes progression of cervical squamous cell carcinoma by inducing epithelial-mesenchymal transition via Wnt signaling.

Song E, Yu W, Xiong X, Kuang X, Ai Y, Xiong X.

Int J Gynecol Cancer. 2015 Mar;25(3):345-55. doi: 10.1097/IGC.0000000000000381.

PMID:
25695541
13.

FOXO3a modulates WNT/β-catenin signaling and suppresses epithelial-to-mesenchymal transition in prostate cancer cells.

Liu H, Yin J, Wang H, Jiang G, Deng M, Zhang G, Bu X, Cai S, Du J, He Z.

Cell Signal. 2015 Mar;27(3):510-8. doi: 10.1016/j.cellsig.2015.01.001. Epub 2015 Jan 8.

PMID:
25578861
14.

The DEAD box protein p68: a crucial regulator of AKT/FOXO3a signaling axis in oncogenesis.

Sarkar M, Khare V, Guturi KK, Das N, Ghosh MK.

Oncogene. 2015 Nov 19;34(47):5843-56. doi: 10.1038/onc.2015.42. Epub 2015 Mar 9.

PMID:
25745998
15.

Astrocyte elevated gene-1 (AEG-1) is a target gene of oncogenic Ha-ras requiring phosphatidylinositol 3-kinase and c-Myc.

Lee SG, Su ZZ, Emdad L, Sarkar D, Fisher PB.

Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17390-5. Epub 2006 Nov 6.

16.

Aldose reductase inhibition prevents colon cancer growth by restoring phosphatase and tensin homolog through modulation of miR-21 and FOXO3a.

Saxena A, Tammali R, Ramana KV, Srivastava SK.

Antioxid Redox Signal. 2013 Apr 10;18(11):1249-62. doi: 10.1089/ars.2012.4643. Epub 2012 Oct 25.

18.

AEG-1 overexpression is essential for maintenance of malignant state in human AML cells via up-regulation of Akt1 mediated by AURKA activation.

Long M, Hao M, Dong K, Shen J, Wang X, Lin F, Liu L, Wei J, Liang Y, Yang J, Gu F, Zhang H.

Cell Signal. 2013 Jun;25(6):1438-46. doi: 10.1016/j.cellsig.2013.03.001. Epub 2013 Mar 14.

PMID:
23499911
19.

AEG-1 is a target of perifosine and is over-expressed in gastric dysplasia and cancers.

Huang W, Yang L, Liang S, Liu D, Chen X, Ma Z, Zhai S, Li P, Wang X.

Dig Dis Sci. 2013 Oct;58(10):2873-80. doi: 10.1007/s10620-013-2735-5. Epub 2013 Aug 4.

PMID:
23912246
20.

Deregulation of FoxO3a accelerates prostate cancer progression in TRAMP mice.

Shukla S, Bhaskaran N, Maclennan GT, Gupta S.

Prostate. 2013 Oct;73(14):1507-17. doi: 10.1002/pros.22698. Epub 2013 Jun 13.

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