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Items: 1 to 20 of 82

1.

Regulation of the Pro-apoptotic scaffolding protein POSH by Akt.

Lyons TR, Thorburn J, Ryan PW, Thorburn A, Anderson SM, Kassenbrock CK.

J Biol Chem. 2007 Jul 27;282(30):21987-97. Epub 2007 May 29.

2.

Akt2 negatively regulates assembly of the POSH-MLK-JNK signaling complex.

Figueroa C, Tarras S, Taylor J, Vojtek AB.

J Biol Chem. 2003 Nov 28;278(48):47922-7. Epub 2003 Sep 21.

3.
4.

Sh3rf2/POSHER protein promotes cell survival by ring-mediated proteasomal degradation of the c-Jun N-terminal kinase scaffold POSH (Plenty of SH3s) protein.

Wilhelm M, Kukekov NV, Schmit TL, Biagas KV, Sproul AA, Gire S, Maes ME, Xu Z, Greene LA.

J Biol Chem. 2012 Jan 13;287(3):2247-56. doi: 10.1074/jbc.M111.269431. Epub 2011 Nov 28.

5.

Proapoptotic Nix activates the JNK pathway by interacting with POSH and mediates death in a Parkinson disease model.

Wilhelm M, Xu Z, Kukekov NV, Gire S, Greene LA.

J Biol Chem. 2007 Jan 12;282(2):1288-95. Epub 2006 Nov 9.

6.

Regulation of the protein stability of POSH and MLK family.

Wang C, Tao Y, Wang Y, Xu Z.

Protein Cell. 2010 Sep;1(9):871-8. doi: 10.1007/s13238-010-0111-1. Epub 2010 Oct 7.

7.

Siah1 interacts with the scaffold protein POSH to promote JNK activation and apoptosis.

Xu Z, Sproul A, Wang W, Kukekov N, Greene LA.

J Biol Chem. 2006 Jan 6;281(1):303-12. Epub 2005 Oct 17.

8.

Possible role of death receptor-mediated apoptosis by the E3 ubiquitin ligases Siah2 and POSH.

Christian PA, Fiandalo MV, Schwarze SR.

Mol Cancer. 2011 May 17;10:57. doi: 10.1186/1476-4598-10-57.

9.

The RING-finger scaffold protein Plenty of SH3s targets TAK1 to control immunity signalling in Drosophila.

Tsuda M, Langmann C, Harden N, Aigaki T.

EMBO Rep. 2005 Nov;6(11):1082-7. Epub 2005 Sep 23.

10.
11.

Novel function of POSH, a JNK scaffold, as an E3 ubiquitin ligase for the Hrs stability on early endosomes.

Kim GH, Park E, Kong YY, Han JK.

Cell Signal. 2006 Apr;18(4):553-63. Epub 2005 Aug 9.

PMID:
16084064
12.
13.

Direct interaction of the molecular scaffolds POSH and JIP is required for apoptotic activation of JNKs.

Kukekov NV, Xu Z, Greene LA.

J Biol Chem. 2006 Jun 2;281(22):15517-24. Epub 2006 Mar 29.

14.

The assembly of POSH-JNK regulates Xenopus anterior neural development.

Kim GH, Park E, Han JK.

Dev Biol. 2005 Oct 1;286(1):256-69.

15.

ArgBP2gamma interacts with Akt and p21-activated kinase-1 and promotes cell survival.

Yuan ZQ, Kim D, Kaneko S, Sussman M, Bokoch GM, Kruh GD, Nicosia SV, Testa JR, Cheng JQ.

J Biol Chem. 2005 Jun 3;280(22):21483-90. Epub 2005 Mar 22. Retraction in: J Biol Chem. 2016 Oct 21;291(43):22845.

16.

Identification of POSH2, a novel homologue of the c-Jun N-terminal kinase scaffold protein POSH.

Wilhelm M, Kukekov NV, Xu Z, Greene LA.

Dev Neurosci. 2007;29(4-5):355-62.

PMID:
17762203
17.

POSH misexpression induces caspase-dependent cell death in Drosophila.

Lennox AL, Stronach B.

Dev Dyn. 2010 Feb;239(2):651-64. doi: 10.1002/dvdy.22186.

18.

Evidence that Ser87 of BimEL is phosphorylated by Akt and regulates BimEL apoptotic function.

Qi XJ, Wildey GM, Howe PH.

J Biol Chem. 2006 Jan 13;281(2):813-23. Epub 2005 Nov 10.

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20.

The PI3-kinase-Akt pathway promotes mesangial cell survival and inhibits apoptosis in vitro via NF-kappa B and Bad.

Shimamura H, Terada Y, Okado T, Tanaka H, Inoshita S, Sasaki S.

J Am Soc Nephrol. 2003 Jun;14(6):1427-34.

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