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Items: 1 to 20 of 187

1.

Structural basis of histone demethylation by LSD1 revealed by suicide inactivation.

Yang M, Culhane JC, Szewczuk LM, Gocke CB, Brautigam CA, Tomchick DR, Machius M, Cole PA, Yu H.

Nat Struct Mol Biol. 2007 Jun;14(6):535-9. Epub 2007 May 27.

PMID:
17529991
2.

Human histone demethylase LSD1 reads the histone code.

Forneris F, Binda C, Vanoni MA, Battaglioli E, Mattevi A.

J Biol Chem. 2005 Dec 16;280(50):41360-5. Epub 2005 Oct 13.

3.

A novel mammalian flavin-dependent histone demethylase.

Karytinos A, Forneris F, Profumo A, Ciossani G, Battaglioli E, Binda C, Mattevi A.

J Biol Chem. 2009 Jun 26;284(26):17775-82. doi: 10.1074/jbc.M109.003087. Epub 2009 Apr 30.

4.

Structural basis for the inhibition of the LSD1 histone demethylase by the antidepressant trans-2-phenylcyclopropylamine.

Yang M, Culhane JC, Szewczuk LM, Jalili P, Ball HL, Machius M, Cole PA, Yu H.

Biochemistry. 2007 Jul 10;46(27):8058-65. Epub 2007 Jun 15.

PMID:
17569509
5.

A highly specific mechanism of histone H3-K4 recognition by histone demethylase LSD1.

Forneris F, Binda C, Dall'Aglio A, Fraaije MW, Battaglioli E, Mattevi A.

J Biol Chem. 2006 Nov 17;281(46):35289-95. Epub 2006 Sep 20.

6.

Structural basis for CoREST-dependent demethylation of nucleosomes by the human LSD1 histone demethylase.

Yang M, Gocke CB, Luo X, Borek D, Tomchick DR, Machius M, Otwinowski Z, Yu H.

Mol Cell. 2006 Aug 4;23(3):377-87.

7.

Histone demethylation mediated by the nuclear amine oxidase homolog LSD1.

Shi Y, Lan F, Matson C, Mulligan P, Whetstine JR, Cole PA, Casero RA, Shi Y.

Cell. 2004 Dec 29;119(7):941-53.

8.

Crystal structure and mechanism of human lysine-specific demethylase-1.

Stavropoulos P, Blobel G, Hoelz A.

Nat Struct Mol Biol. 2006 Jul;13(7):626-32. Epub 2006 Jun 25.

PMID:
16799558
9.

Crystal structure of histone demethylase LSD1 and tranylcypromine at 2.25 A.

Mimasu S, Sengoku T, Fukuzawa S, Umehara T, Yokoyama S.

Biochem Biophys Res Commun. 2008 Feb 1;366(1):15-22. Epub 2007 Nov 26.

PMID:
18039463
10.

New roles of flavoproteins in molecular cell biology: histone demethylase LSD1 and chromatin.

Forneris F, Battaglioli E, Mattevi A, Binda C.

FEBS J. 2009 Aug;276(16):4304-12. doi: 10.1111/j.1742-4658.2009.07142.x. Epub 2009 Jul 14. Review.

11.

Histone demethylation catalysed by LSD1 is a flavin-dependent oxidative process.

Forneris F, Binda C, Vanoni MA, Mattevi A, Battaglioli E.

FEBS Lett. 2005 Apr 11;579(10):2203-7.

12.

Solution structure of the SWIRM domain of human histone demethylase LSD1.

Tochio N, Umehara T, Koshiba S, Inoue M, Yabuki T, Aoki M, Seki E, Watanabe S, Tomo Y, Hanada M, Ikari M, Sato M, Terada T, Nagase T, Ohara O, Shirouzu M, Tanaka A, Kigawa T, Yokoyama S.

Structure. 2006 Mar;14(3):457-68.

13.

Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression.

Lan F, Collins RE, De Cegli R, Alpatov R, Horton JR, Shi X, Gozani O, Cheng X, Shi Y.

Nature. 2007 Aug 9;448(7154):718-22.

14.

Lysine-specific demethylase 1 (LSD1) Is required for the transcriptional repression of the telomerase reverse transcriptase (hTERT) gene.

Zhu Q, Liu C, Ge Z, Fang X, Zhang X, Strååt K, Björkholm M, Xu D.

PLoS One. 2008 Jan 16;3(1):e1446. doi: 10.1371/journal.pone.0001446.

15.

Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity.

Ng SS, Kavanagh KL, McDonough MA, Butler D, Pilka ES, Lienard BM, Bray JE, Savitsky P, Gileadi O, von Delft F, Rose NR, Offer J, Scheinost JC, Borowski T, Sundstrom M, Schofield CJ, Oppermann U.

Nature. 2007 Jul 5;448(7149):87-91. Epub 2007 Jun 24.

PMID:
17589501
16.

Crystal structure of human histone lysine-specific demethylase 1 (LSD1).

Chen Y, Yang Y, Wang F, Wan K, Yamane K, Zhang Y, Lei M.

Proc Natl Acad Sci U S A. 2006 Sep 19;103(38):13956-61. Epub 2006 Sep 6.

17.

LSD1: oxidative chemistry for multifaceted functions in chromatin regulation.

Forneris F, Binda C, Battaglioli E, Mattevi A.

Trends Biochem Sci. 2008 Apr;33(4):181-9. doi: 10.1016/j.tibs.2008.01.003. Epub 2008 Mar 17. Review.

PMID:
18343668
18.

Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expression.

Wissmann M, Yin N, Müller JM, Greschik H, Fodor BD, Jenuwein T, Vogler C, Schneider R, Günther T, Buettner R, Metzger E, Schüle R.

Nat Cell Biol. 2007 Mar;9(3):347-53. Epub 2007 Feb 4.

PMID:
17277772
19.

A mechanism-based inactivator for histone demethylase LSD1.

Culhane JC, Szewczuk LM, Liu X, Da G, Marmorstein R, Cole PA.

J Am Chem Soc. 2006 Apr 12;128(14):4536-7.

PMID:
16594666
20.

LSD1 demethylates histone and non-histone proteins.

Nicholson TB, Chen T.

Epigenetics. 2009 Apr 1;4(3):129-32. Epub 2009 Apr 14.

PMID:
19395867

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