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Items: 1 to 20 of 248

1.

Pph3-Psy2 is a phosphatase complex required for Rad53 dephosphorylation and replication fork restart during recovery from DNA damage.

O'Neill BM, Szyjka SJ, Lis ET, Bailey AO, Yates JR 3rd, Aparicio OM, Romesberg FE.

Proc Natl Acad Sci U S A. 2007 May 29;104(22):9290-5. Epub 2007 May 21.

2.

Rad53 regulates replication fork restart after DNA damage in Saccharomyces cerevisiae.

Szyjka SJ, Aparicio JG, Viggiani CJ, Knott S, Xu W, Tavaré S, Aparicio OM.

Genes Dev. 2008 Jul 15;22(14):1906-20. doi: 10.1101/gad.1660408.

3.

Protein phosphatase Pph3 and its regulatory subunit Psy2 regulate Rad53 dephosphorylation and cell morphogenesis during recovery from DNA damage in Candida albicans.

Sun LL, Li WJ, Wang HT, Chen J, Deng P, Wang Y, Sang JL.

Eukaryot Cell. 2011 Nov;10(11):1565-73. doi: 10.1128/EC.05042-11. Epub 2011 Sep 2.

4.

Distinct phosphatases mediate the deactivation of the DNA damage checkpoint kinase Rad53.

Travesa A, Duch A, Quintana DG.

J Biol Chem. 2008 Jun 20;283(25):17123-30. doi: 10.1074/jbc.M801402200. Epub 2008 Apr 25.

5.

Dephosphorylation of gamma H2A by Glc7/protein phosphatase 1 promotes recovery from inhibition of DNA replication.

Bazzi M, Mantiero D, Trovesi C, Lucchini G, Longhese MP.

Mol Cell Biol. 2010 Jan;30(1):131-45. doi: 10.1128/MCB.01000-09.

6.

Regulation of tolerance to DNA alkylating damage by Dot1 and Rad53 in Saccharomyces cerevisiae.

Conde F, Ontoso D, Acosta I, Gallego-Sánchez A, Bueno A, San-Segundo PA.

DNA Repair (Amst). 2010 Oct 5;9(10):1038-49. doi: 10.1016/j.dnarep.2010.07.003. Epub 2010 Jul 31.

PMID:
20674515
7.

Pph3 dephosphorylation of Rad53 is required for cell recovery from MMS-induced DNA damage in Candida albicans.

Wang H, Gao J, Li W, Wong AH, Hu K, Chen K, Wang Y, Sang J.

PLoS One. 2012;7(5):e37246. doi: 10.1371/journal.pone.0037246. Epub 2012 May 14.

8.

Characterization of Pph3-mediated dephosphorylation of Rad53 during methyl methanesulfonate-induced DNA damage repair in Candida albicans.

Yao G, Wan J, Liu Q, Mu C, Wang Y, Sang J.

Biochem J. 2017 Mar 23;474(7):1293-1306. doi: 10.1042/BCJ20160889.

PMID:
28183985
9.

Rad53 kinase activation-independent replication checkpoint function of the N-terminal forkhead-associated (FHA1) domain.

Pike BL, Tenis N, Heierhorst J.

J Biol Chem. 2004 Sep 17;279(38):39636-44. Epub 2004 Jul 22.

10.

Rad53-Mediated Regulation of Rrm3 and Pif1 DNA Helicases Contributes to Prevention of Aberrant Fork Transitions under Replication Stress.

Rossi SE, Ajazi A, Carotenuto W, Foiani M, Giannattasio M.

Cell Rep. 2015 Oct 6;13(1):80-92. doi: 10.1016/j.celrep.2015.08.073. Epub 2015 Sep 24.

11.

ORC and the intra-S-phase checkpoint: a threshold regulates Rad53p activation in S phase.

Shimada K, Pasero P, Gasser SM.

Genes Dev. 2002 Dec 15;16(24):3236-52.

12.

Termination of Replication Stress Signaling via Concerted Action of the Slx4 Scaffold and the PP4 Phosphatase.

Jablonowski CM, Cussiol JR, Oberly S, Yimit A, Balint A, Kim T, Zhang Z, Brown GW, Smolka MB.

Genetics. 2015 Nov;201(3):937-49. doi: 10.1534/genetics.115.181479. Epub 2015 Sep 11.

13.

Damage-induced phosphorylation of Sld3 is important to block late origin firing.

Lopez-Mosqueda J, Maas NL, Jonsson ZO, Defazio-Eli LG, Wohlschlegel J, Toczyski DP.

Nature. 2010 Sep 23;467(7314):479-83. doi: 10.1038/nature09377.

14.

Separate roles for the DNA damage checkpoint protein kinases in stabilizing DNA replication forks.

Segurado M, Diffley JF.

Genes Dev. 2008 Jul 1;22(13):1816-27. doi: 10.1101/gad.477208.

15.

Requirement of replication checkpoint protein kinases Mec1/Rad53 for postreplication repair in yeast.

Gangavarapu V, Santa Maria SR, Prakash S, Prakash L.

MBio. 2011 May 17;2(3):e00079-11. doi: 10.1128/mBio.00079-11. Print 2011.

16.

A Dbf4 mutant contributes to bypassing the Rad53-mediated block of origins of replication in response to genotoxic stress.

Duch A, Palou G, Jonsson ZO, Palou R, Calvo E, Wohlschlegel J, Quintana DG.

J Biol Chem. 2011 Jan 28;286(4):2486-91. doi: 10.1074/jbc.M110.190843. Epub 2010 Nov 23.

17.

Spk1/Rad53 is regulated by Mec1-dependent protein phosphorylation in DNA replication and damage checkpoint pathways.

Sun Z, Fay DS, Marini F, Foiani M, Stern DF.

Genes Dev. 1996 Feb 15;10(4):395-406.

18.

Mechanisms of checkpoint kinase Rad53 inactivation after a double-strand break in Saccharomyces cerevisiae.

Guillemain G, Ma E, Mauger S, Miron S, Thai R, Guérois R, Ochsenbein F, Marsolier-Kergoat MC.

Mol Cell Biol. 2007 May;27(9):3378-89. Epub 2007 Feb 26.

19.

A kinase's work is never done: Rad53 monitors chromatin near replication origins.

Formosa T.

Cell Cycle. 2011 Feb 15;10(4):573-4. Epub 2011 Feb 15. No abstract available.

PMID:
21311236
20.

Molecular basis of the essential s phase function of the rad53 checkpoint kinase.

Hoch NC, Chen ES, Buckland R, Wang SC, Fazio A, Hammet A, Pellicioli A, Chabes A, Tsai MD, Heierhorst J.

Mol Cell Biol. 2013 Aug;33(16):3202-13. doi: 10.1128/MCB.00474-13. Epub 2013 Jun 10.

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