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Items: 1 to 20 of 106

1.

Impaired in vitro regulatory T cell function associated with Wiskott-Aldrich syndrome.

Adriani M, Aoki J, Horai R, Thornton AM, Konno A, Kirby M, Anderson SM, Siegel RM, Candotti F, Schwartzberg PL.

Clin Immunol. 2007 Jul;124(1):41-8. Epub 2007 May 18.

2.

Wiskott-Aldrich syndrome protein is required for regulatory T cell homeostasis.

Humblet-Baron S, Sather B, Anover S, Becker-Herman S, Kasprowicz DJ, Khim S, Nguyen T, Hudkins-Loya K, Alpers CE, Ziegler SF, Ochs H, Torgerson T, Campbell DJ, Rawlings DJ.

J Clin Invest. 2007 Feb;117(2):407-18. Epub 2007 Jan 11.

3.

The Wiskott-Aldrich syndrome protein is required for the function of CD4(+)CD25(+)Foxp3(+) regulatory T cells.

Maillard MH, Cotta-de-Almeida V, Takeshima F, Nguyen DD, Michetti P, Nagler C, Bhan AK, Snapper SB.

J Exp Med. 2007 Feb 19;204(2):381-91. Epub 2007 Feb 12.

4.

Effects of Wiskott-Aldrich Syndrome Protein Deficiency on IL-10-Producing Regulatory B Cells in Humans and Mice.

Du HQ, Zhang X, An YF, Ding Y, Zhao XD.

Scand J Immunol. 2015 Jun;81(6):483-93. doi: 10.1111/sji.12282.

5.

WASP regulates suppressor activity of human and murine CD4(+)CD25(+)FOXP3(+) natural regulatory T cells.

Marangoni F, Trifari S, Scaramuzza S, Panaroni C, Martino S, Notarangelo LD, Baz Z, Metin A, Cattaneo F, Villa A, Aiuti A, Battaglia M, Roncarolo MG, Dupré L.

J Exp Med. 2007 Feb 19;204(2):369-80. Epub 2007 Feb 12.

6.

Wiskott-Aldrich syndrome protein deficiency in innate immune cells leads to mucosal immune dysregulation and colitis in mice.

Nguyen DD, Wurbel MA, Goettel JA, Eston MA, Ahmed OS, Marin R, Boden EK, Villablanca EJ, Paidassi H, Ahuja V, Reinecker HC, Fiebiger E, Lacy-Hulbert A, Horwitz BH, Mora JR, Snapper SB.

Gastroenterology. 2012 Sep;143(3):719-729.e2. doi: 10.1053/j.gastro.2012.06.008. Epub 2012 Jun 15.

7.

Lymphocyte-dependent and Th2 cytokine-associated colitis in mice deficient in Wiskott-Aldrich syndrome protein.

Nguyen DD, Maillard MH, Cotta-de-Almeida V, Mizoguchi E, Klein C, Fuss I, Nagler C, Mizoguchi A, Bhan AK, Snapper SB.

Gastroenterology. 2007 Oct;133(4):1188-97. Epub 2007 Jul 12.

8.

N-WASP is required for B-cell-mediated autoimmunity in Wiskott-Aldrich syndrome.

Volpi S, Santori E, Abernethy K, Mizui M, Dahlberg CI, Recher M, Capuder K, Csizmadia E, Ryan D, Mathew D, Tsokos GC, Snapper S, Westerberg LS, Thrasher AJ, Candotti F, Notarangelo LD.

Blood. 2016 Jan 14;127(2):216-20. doi: 10.1182/blood-2015-05-643817. Epub 2015 Oct 14.

9.

Wiskott-Aldrich Syndrome protein deficiency perturbs the homeostasis of B-cell compartment in humans.

Castiello MC, Bosticardo M, Pala F, Catucci M, Chamberlain N, van Zelm MC, Driessen GJ, Pac M, Bernatowska E, Scaramuzza S, Aiuti A, Sauer AV, Traggiai E, Meffre E, Villa A, van der Burg M.

J Autoimmun. 2014 May;50:42-50. doi: 10.1016/j.jaut.2013.10.006. Epub 2013 Dec 25.

10.

Antigen receptor-induced activation and cytoskeletal rearrangement are impaired in Wiskott-Aldrich syndrome protein-deficient lymphocytes.

Zhang J, Shehabeldin A, da Cruz LA, Butler J, Somani AK, McGavin M, Kozieradzki I, dos Santos AO, Nagy A, Grinstein S, Penninger JM, Siminovitch KA.

J Exp Med. 1999 Nov 1;190(9):1329-42.

11.

Exacerbated experimental arthritis in Wiskott-Aldrich syndrome protein deficiency: modulatory role of regulatory B cells.

Bouma G, Carter NA, Recher M, Malinova D, Adriani M, Notarangelo LD, Burns SO, Mauri C, Thrasher AJ.

Eur J Immunol. 2014 Sep;44(9):2692-702. doi: 10.1002/eji.201344245. Epub 2014 Jul 15.

12.

Wiskott-Aldrich Syndrome at the nexus of autoimmune and primary immunodeficiency diseases.

Cleland SY, Siegel RM.

FEBS Lett. 2011 Dec 1;585(23):3710-4. doi: 10.1016/j.febslet.2011.10.031. Epub 2011 Oct 25. Review.

13.

Abnormalities of follicular helper T-cell number and function in Wiskott-Aldrich syndrome.

Zhang X, Dai R, Li W, Zhao H, Zhang Y, Zhou L, Du H, Luo G, Wu J, Niu L, An Y, Zhang Z, Ding Y, Song W, Liu C, Zhao X.

Blood. 2016 Jun 23;127(25):3180-91. doi: 10.1182/blood-2015-06-652636. Epub 2016 May 11.

14.

WASP: a key immunological multitasker.

Thrasher AJ, Burns SO.

Nat Rev Immunol. 2010 Mar;10(3):182-92. doi: 10.1038/nri2724. Review.

PMID:
20182458
15.

Reduced type I interferon production by dendritic cells and weakened antiviral immunity in patients with Wiskott-Aldrich syndrome protein deficiency.

Lang PA, Shaabani N, Borkens S, Honke N, Scheu S, Booth S, Brenner D, Meryk A, Barthuber C, Recher M, Mak TW, Ohashi PS, Häussinger D, Griffiths GM, Thrasher AJ, Bouma G, Lang KS.

J Allergy Clin Immunol. 2013 Mar;131(3):815-24. doi: 10.1016/j.jaci.2012.08.050. Epub 2012 Nov 6.

16.

Lentiviral-mediated gene therapy restores B cell tolerance in Wiskott-Aldrich syndrome patients.

Pala F, Morbach H, Castiello MC, Schickel JN, Scaramuzza S, Chamberlain N, Cassani B, Glauzy S, Romberg N, Candotti F, Aiuti A, Bosticardo M, Villa A, Meffre E.

J Clin Invest. 2015 Oct 1;125(10):3941-51. doi: 10.1172/JCI82249. Epub 2015 Sep 14.

17.

Wiskott-Aldrich syndrome protein-mediated actin dynamics control type-I interferon production in plasmacytoid dendritic cells.

Prete F, Catucci M, Labrada M, Gobessi S, Castiello MC, Bonomi E, Aiuti A, Vermi W, Cancrini C, Metin A, Hambleton S, Bredius R, Notarangelo LD, van der Burg M, Kalinke U, Villa A, Benvenuti F.

J Exp Med. 2013 Feb 11;210(2):355-74. doi: 10.1084/jem.20120363. Epub 2013 Jan 21.

18.

Wiskott-Aldrich Syndrome causing mutation, Pro373Ser restricts conformational changes essential for WASP activity in T-cells.

Jain N, George B, Thanabalu T.

Biochim Biophys Acta. 2014 Apr;1842(4):623-34. doi: 10.1016/j.bbadis.2014.01.006. Epub 2014 Jan 15.

19.

Critical requirement for the Wiskott-Aldrich syndrome protein in Th2 effector function.

Morales-Tirado V, Sojka DK, Katzman SD, Lazarski CA, Finkelman FD, Urban JF, Fowell DJ.

Blood. 2010 Apr 29;115(17):3498-507. doi: 10.1182/blood-2009-07-235754. Epub 2009 Dec 23.

20.

The Wiskott-Aldrich syndrome: The actin cytoskeleton and immune cell function.

Blundell MP, Worth A, Bouma G, Thrasher AJ.

Dis Markers. 2010;29(3-4):157-75. doi: 10.3233/DMA-2010-0735. Review.

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