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Items: 1 to 20 of 145

1.

Characterization of heme as activator of Toll-like receptor 4.

Figueiredo RT, Fernandez PL, Mourao-Sa DS, Porto BN, Dutra FF, Alves LS, Oliveira MF, Oliveira PL, Graça-Souza AV, Bozza MT.

J Biol Chem. 2007 Jul 13;282(28):20221-9. Epub 2007 May 14.

2.
3.

Analysis of proteinase-activated receptor 2 and TLR4 signal transduction: a novel paradigm for receptor cooperativity.

Rallabhandi P, Nhu QM, Toshchakov VY, Piao W, Medvedev AE, Hollenberg MD, Fasano A, Vogel SN.

J Biol Chem. 2008 Sep 5;283(36):24314-25. doi: 10.1074/jbc.M804800200. Epub 2008 Jul 11.

4.

CD14 dependence of TLR4 endocytosis and TRIF signaling displays ligand specificity and is dissociable in endotoxin tolerance.

Rajaiah R, Perkins DJ, Ireland DD, Vogel SN.

Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):8391-6. doi: 10.1073/pnas.1424980112. Epub 2015 Jun 23.

5.

Molecular mechanism for adiponectin-dependent M2 macrophage polarization: link between the metabolic and innate immune activity of full-length adiponectin.

Mandal P, Pratt BT, Barnes M, McMullen MR, Nagy LE.

J Biol Chem. 2011 Apr 15;286(15):13460-9. doi: 10.1074/jbc.M110.204644. Epub 2011 Feb 25.

6.

Activation of Toll-like receptors by Burkholderia pseudomallei.

West TE, Ernst RK, Jansson-Hutson MJ, Skerrett SJ.

BMC Immunol. 2008 Aug 8;9:46. doi: 10.1186/1471-2172-9-46.

7.

Heme activates TLR4-mediated inflammatory injury via MyD88/TRIF signaling pathway in intracerebral hemorrhage.

Lin S, Yin Q, Zhong Q, Lv FL, Zhou Y, Li JQ, Wang JZ, Su BY, Yang QW.

J Neuroinflammation. 2012 Mar 6;9:46. doi: 10.1186/1742-2094-9-46.

8.

Melatonin modulates TLR4-mediated inflammatory genes through MyD88- and TRIF-dependent signaling pathways in lipopolysaccharide-stimulated RAW264.7 cells.

Xia MZ, Liang YL, Wang H, Chen X, Huang YY, Zhang ZH, Chen YH, Zhang C, Zhao M, Xu DX, Song LH.

J Pineal Res. 2012 Nov;53(4):325-34. doi: 10.1111/j.1600-079X.2012.01002.x. Epub 2012 Apr 27.

PMID:
22537289
9.

B and T lymphocyte attenuator inhibits LPS-induced endotoxic shock by suppressing Toll-like receptor 4 signaling in innate immune cells.

Kobayashi Y, Iwata A, Suzuki K, Suto A, Kawashima S, Saito Y, Owada T, Kobayashi M, Watanabe N, Nakajima H.

Proc Natl Acad Sci U S A. 2013 Mar 26;110(13):5121-6. doi: 10.1073/pnas.1222093110. Epub 2013 Mar 11.

10.

CD36 Differently Regulates Macrophage Responses to Smooth and Rough Lipopolysaccharide.

Biedroń R, Peruń A, Józefowski S.

PLoS One. 2016 Apr 13;11(4):e0153558. doi: 10.1371/journal.pone.0153558. eCollection 2016.

11.

TLR4-mediated survival of macrophages is MyD88 dependent and requires TNF-alpha autocrine signalling.

Lombardo E, Alvarez-Barrientos A, Maroto B, Boscá L, Knaus UG.

J Immunol. 2007 Mar 15;178(6):3731-9.

12.

Differing effects of exogenous or endogenous cathelicidin on macrophage toll-like receptor signaling.

Pinheiro da Silva F, Gallo RL, Nizet V.

Immunol Cell Biol. 2009 Aug-Sep;87(6):496-500. doi: 10.1038/icb.2009.19. Epub 2009 Apr 7.

13.

Mycobacterial phosphatidylinositol mannosides negatively regulate host Toll-like receptor 4, MyD88-dependent proinflammatory cytokines, and TRIF-dependent co-stimulatory molecule expression.

Doz E, Rose S, Court N, Front S, Vasseur V, Charron S, Gilleron M, Puzo G, Fremaux I, Delneste Y, Erard F, Ryffel B, Martin OR, Quesniaux VF.

J Biol Chem. 2009 Aug 28;284(35):23187-96. doi: 10.1074/jbc.M109.037846. Epub 2009 Jun 26.

14.

Differential induction of the toll-like receptor 4-MyD88-dependent and -independent signaling pathways by endotoxins.

Zughaier SM, Zimmer SM, Datta A, Carlson RW, Stephens DS.

Infect Immun. 2005 May;73(5):2940-50. Erratum in: Infect Immun. 2006 May;74(5):3077.

15.

Bupleurum polysaccharides attenuates lipopolysaccharide-induced inflammation via modulating Toll-like receptor 4 signaling.

Wu J, Zhang YY, Guo L, Li H, Chen DF.

PLoS One. 2013 Oct 22;8(10):e78051. doi: 10.1371/journal.pone.0078051. eCollection 2013.

17.

Quercetin disrupts tyrosine-phosphorylated phosphatidylinositol 3-kinase and myeloid differentiation factor-88 association, and inhibits MAPK/AP-1 and IKK/NF-κB-induced inflammatory mediators production in RAW 264.7 cells.

Endale M, Park SC, Kim S, Kim SH, Yang Y, Cho JY, Rhee MH.

Immunobiology. 2013 Dec;218(12):1452-67. doi: 10.1016/j.imbio.2013.04.019. Epub 2013 May 9.

PMID:
23735482
18.

Differential role for p120-catenin in regulation of TLR4 signaling in macrophages.

Yang Z, Sun D, Yan Z, Reynolds AB, Christman JW, Minshall RD, Malik AB, Zhang Y, Hu G.

J Immunol. 2014 Aug 15;193(4):1931-41. doi: 10.4049/jimmunol.1302863. Epub 2014 Jul 11.

19.

Lysosome-associated small Rab GTPase Rab7b negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4.

Wang Y, Chen T, Han C, He D, Liu H, An H, Cai Z, Cao X.

Blood. 2007 Aug 1;110(3):962-71. Epub 2007 Mar 29.

20.

TAK-242 selectively suppresses Toll-like receptor 4-signaling mediated by the intracellular domain.

Kawamoto T, Ii M, Kitazaki T, Iizawa Y, Kimura H.

Eur J Pharmacol. 2008 Apr 14;584(1):40-8. doi: 10.1016/j.ejphar.2008.01.026. Epub 2008 Feb 5.

PMID:
18299127

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