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Items: 1 to 20 of 110

1.

Interaction of amyloid binding alcohol dehydrogenase/Abeta mediates up-regulation of peroxiredoxin II in the brains of Alzheimer's disease patients and a transgenic Alzheimer's disease mouse model.

Yao J, Taylor M, Davey F, Ren Y, Aiton J, Coote P, Fang F, Chen JX, Yan SD, Gunn-Moore FJ.

Mol Cell Neurosci. 2007 Jun;35(2):377-82. Epub 2007 Apr 1.

PMID:
17490890
2.

Inhibition of amyloid-beta (Abeta) peptide-binding alcohol dehydrogenase-Abeta interaction reduces Abeta accumulation and improves mitochondrial function in a mouse model of Alzheimer's disease.

Yao J, Du H, Yan S, Fang F, Wang C, Lue LF, Guo L, Chen D, Stern DM, Gunn Moore FJ, Xi Chen J, Arancio O, Yan SS.

J Neurosci. 2011 Feb 9;31(6):2313-20. doi: 10.1523/JNEUROSCI.4717-10.2011.

3.

Endophilin I expression is increased in the brains of Alzheimer disease patients.

Ren Y, Xu HW, Davey F, Taylor M, Aiton J, Coote P, Fang F, Yao J, Chen D, Chen JX, Yan SD, Gunn-Moore FJ.

J Biol Chem. 2008 Feb 29;283(9):5685-91. doi: 10.1074/jbc.M707932200. Epub 2007 Dec 31.

4.

Methylene Blue Improves Brain Mitochondrial ABAD Functions and Decreases Aβ in a Neuroinflammatory Alzheimer's Disease Mouse Model.

Zakaria A, Hamdi N, Abdel-Kader RM.

Mol Neurobiol. 2016 Mar;53(2):1220-8. doi: 10.1007/s12035-014-9088-8. Epub 2015 Jan 20.

PMID:
25601181
5.
6.

Progressive accumulation of amyloid-beta oligomers in Alzheimer's disease and in amyloid precursor protein transgenic mice is accompanied by selective alterations in synaptic scaffold proteins.

Pham E, Crews L, Ubhi K, Hansen L, Adame A, Cartier A, Salmon D, Galasko D, Michael S, Savas JN, Yates JR, Glabe C, Masliah E.

FEBS J. 2010 Jul;277(14):3051-67. doi: 10.1111/j.1742-4658.2010.07719.x. Epub 2010 Jun 22.

7.

ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease.

Lustbader JW, Cirilli M, Lin C, Xu HW, Takuma K, Wang N, Caspersen C, Chen X, Pollak S, Chaney M, Trinchese F, Liu S, Gunn-Moore F, Lue LF, Walker DG, Kuppusamy P, Zewier ZL, Arancio O, Stern D, Yan SS, Wu H.

Science. 2004 Apr 16;304(5669):448-52.

8.

ABAD enhances Abeta-induced cell stress via mitochondrial dysfunction.

Takuma K, Yao J, Huang J, Xu H, Chen X, Luddy J, Trillat AC, Stern DM, Arancio O, Yan SS.

FASEB J. 2005 Apr;19(6):597-8. Epub 2005 Jan 21.

PMID:
15665036
9.

Genetic inhibition of phosphorylation of the translation initiation factor eIF2α does not block Aβ-dependent elevation of BACE1 and APP levels or reduce amyloid pathology in a mouse model of Alzheimer's disease.

Sadleir KR, Eimer WA, Kaufman RJ, Osten P, Vassar R.

PLoS One. 2014 Jul 3;9(7):e101643. doi: 10.1371/journal.pone.0101643. eCollection 2014. Erratum in: PLoS One. 2014;9(10):e110914.

10.

Suppression of Alzheimer's disease-related phenotypes by expression of heat shock protein 70 in mice.

Hoshino T, Murao N, Namba T, Takehara M, Adachi H, Katsuno M, Sobue G, Matsushima T, Suzuki T, Mizushima T.

J Neurosci. 2011 Apr 6;31(14):5225-34. doi: 10.1523/JNEUROSCI.5478-10.2011.

11.

Huntingtin associated protein 1 regulates trafficking of the amyloid precursor protein and modulates amyloid beta levels in neurons.

Yang GZ, Yang M, Lim Y, Lu JJ, Wang TH, Qi JG, Zhong JH, Zhou XF.

J Neurochem. 2012 Sep;122(5):1010-22. doi: 10.1111/j.1471-4159.2012.07845.x.

12.

Interactions between amyloid-β and hemoglobin: implications for amyloid plaque formation in Alzheimer's disease.

Chuang JY, Lee CW, Shih YH, Yang T, Yu L, Kuo YM.

PLoS One. 2012;7(3):e33120. doi: 10.1371/journal.pone.0033120. Epub 2012 Mar 6.

13.

p75NTR ectodomain is a physiological neuroprotective molecule against amyloid-beta toxicity in the brain of Alzheimer's disease.

Yao XQ, Jiao SS, Saadipour K, Zeng F, Wang QH, Zhu C, Shen LL, Zeng GH, Liang CR, Wang J, Liu YH, Hou HY, Xu X, Su YP, Fan XT, Xiao HL, Lue LF, Zeng YQ, Giunta B, Zhong JH, Walker DG, Zhou HD, Tan J, Zhou XF, Wang YJ.

Mol Psychiatry. 2015 Nov;20(11):1301-10. doi: 10.1038/mp.2015.49. Epub 2015 Apr 28.

14.

Deletion of Mint proteins decreases amyloid production in transgenic mouse models of Alzheimer's disease.

Ho A, Liu X, Südhof TC.

J Neurosci. 2008 Dec 31;28(53):14392-400. doi: 10.1523/JNEUROSCI.2481-08.2008.

15.

Tyk2/STAT3 signaling mediates beta-amyloid-induced neuronal cell death: implications in Alzheimer's disease.

Wan J, Fu AK, Ip FC, Ng HK, Hugon J, Page G, Wang JH, Lai KO, Wu Z, Ip NY.

J Neurosci. 2010 May 19;30(20):6873-81. doi: 10.1523/JNEUROSCI.0519-10.2010.

16.

Deposition of C-terminally truncated Aβ species Aβ37 and Aβ39 in Alzheimer's disease and transgenic mouse models.

Reinert J, Richard BC, Klafki HW, Friedrich B, Bayer TA, Wiltfang J, Kovacs GG, Ingelsson M, Lannfelt L, Paetau A, Bergquist J, Wirths O.

Acta Neuropathol Commun. 2016 Mar 8;4:24. doi: 10.1186/s40478-016-0294-7.

17.

Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models.

Natunen T, Takalo M, Kemppainen S, Leskelä S, Marttinen M, Kurkinen KMA, Pursiheimo JP, Sarajärvi T, Viswanathan J, Gabbouj S, Solje E, Tahvanainen E, Pirttimäki T, Kurki M, Paananen J, Rauramaa T, Miettinen P, Mäkinen P, Leinonen V, Soininen H, Airenne K, Tanzi RE, Tanila H, Haapasalo A, Hiltunen M.

Neurobiol Dis. 2016 Jan;85:187-205. doi: 10.1016/j.nbd.2015.11.005. Epub 2015 Nov 10.

PMID:
26563932
18.

Mitochondrial β-amyloid in Alzheimer's disease.

Borger E, Aitken L, Muirhead KE, Allen ZE, Ainge JA, Conway SJ, Gunn-Moore FJ.

Biochem Soc Trans. 2011 Aug;39(4):868-73. doi: 10.1042/BST0390868.

PMID:
21787315
19.

Isoglutaminyl cyclase contributes to CCL2-driven neuroinflammation in Alzheimer's disease.

Hartlage-Rübsamen M, Waniek A, Meissner J, Morawski M, Schilling S, Jäger C, Kleinschmidt M, Cynis H, Kehlen A, Arendt T, Demuth HU, Rossner S.

Acta Neuropathol. 2015 Apr;129(4):565-83. doi: 10.1007/s00401-015-1395-2. Epub 2015 Feb 11.

20.

Butyrylcholinesterase-knockout reduces brain deposition of fibrillar β-amyloid in an Alzheimer mouse model.

Reid GA, Darvesh S.

Neuroscience. 2015 Jul 9;298:424-35. doi: 10.1016/j.neuroscience.2015.04.039. Epub 2015 Apr 27.

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