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Items: 1 to 20 of 82

1.

The crystal structure of the ivy Delta4-16:0-ACP desaturase reveals structural details of the oxidized active site and potential determinants of regioselectivity.

Guy JE, Whittle E, Kumaran D, Lindqvist Y, Shanklin J.

J Biol Chem. 2007 Jul 6;282(27):19863-71. Epub 2007 Apr 26.

2.

A multifunctional acyl-acyl carrier protein desaturase from Hedera helix L. (English ivy) can synthesize 16- and 18-carbon monoene and diene products.

Whittle E, Cahoon EB, Subrahmanyam S, Shanklin J.

J Biol Chem. 2005 Aug 5;280(31):28169-76. Epub 2005 Jun 6.

5.

Resonance Raman evidence for an Fe-O-Fe center in stearoyl-ACP desaturase. Primary sequence identity with other diiron-oxo proteins.

Fox BG, Shanklin J, Ai J, Loehr TM, Sanders-Loehr J.

Biochemistry. 1994 Nov 1;33(43):12776-86.

PMID:
7947683
6.

Remote control of regioselectivity in acyl-acyl carrier protein-desaturases.

Guy JE, Whittle E, Moche M, Lengqvist J, Lindqvist Y, Shanklin J.

Proc Natl Acad Sci U S A. 2011 Oct 4;108(40):16594-9. doi: 10.1073/pnas.1110221108. Epub 2011 Sep 19.

7.
9.

Stereochemistry of Delta4 dehydrogenation catalyzed by an ivy (Hedera helix) Delta9 desaturase homolog.

Tremblay AE, Whittle E, Buist PH, Shanklin J.

Org Biomol Chem. 2007 Apr 21;5(8):1270-5. Epub 2007 Mar 19.

PMID:
17406726
10.

Stearoyl-acyl carrier protein delta 9 desaturase from Ricinus communis is a diiron-oxo protein.

Fox BG, Shanklin J, Somerville C, Münck E.

Proc Natl Acad Sci U S A. 1993 Mar 15;90(6):2486-90.

12.

Resonance Raman studies of the stoichiometric catalytic turnover of a substrate-stearoyl-acyl carrier protein delta(9) desaturase complex.

Lyle KS, Möenne-Loccoz P, Ai J, Sanders-Loehr J, Loehr TM, Fox BG.

Biochemistry. 2000 Aug 29;39(34):10507-13.

PMID:
10956041
13.

Geometry of the soluble methane monooxygenase catalytic diiron center in two oxidation states.

Rosenzweig AC, Nordlund P, Takahara PM, Frederick CA, Lippard SJ.

Chem Biol. 1995 Sep;2(9):409-18.

PMID:
9432288
14.

Geometry of the soluble methane monooxygenase catalytic diiron center in two oxidation states.

Rosenzweig AC, Nordlund P, Takahara PM, Frederick CA, Lippard SJ.

Chem Biol. 1995 Jun;2(6):409-18. Corrected and republished in: Chem Biol. 1995 Sep;2(9):409-18.

PMID:
9383443
15.
16.

Revealing the catalytic potential of an acyl-ACP desaturase: tandem selective oxidation of saturated fatty acids.

Whittle EJ, Tremblay AE, Buist PH, Shanklin J.

Proc Natl Acad Sci U S A. 2008 Sep 23;105(38):14738-43. doi: 10.1073/pnas.0805645105. Epub 2008 Sep 16.

17.
18.

Desaturation of trans-octadecenoyl-acyl carrier protein by stearoyl-acyl carrier protein delta9 desaturase.

Broadwater JA, Laundre BJ, Fox BG.

J Inorg Biochem. 2000 Jan 15;78(1):7-14.

PMID:
10714700
19.

X-ray crystallographic studies on butyryl-ACP reveal flexibility of the structure around a putative acyl chain binding site.

Roujeinikova A, Baldock C, Simon WJ, Gilroy J, Baker PJ, Stuitje AR, Rice DW, Slabas AR, Rafferty JB.

Structure. 2002 Jun;10(6):825-35.

20.

Crystallographic analysis of active site contributions to regiospecificity in the diiron enzyme toluene 4-monooxygenase.

Bailey LJ, Acheson JF, McCoy JG, Elsen NL, Phillips GN Jr, Fox BG.

Biochemistry. 2012 Feb 14;51(6):1101-13. doi: 10.1021/bi2018333. Epub 2012 Feb 2.

PMID:
22264099

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