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Borrelia burgdorferi intercepts host hormonal signals to regulate expression of outer surface protein A.

Scheckelhoff MR, Telford SR, Wesley M, Hu LT.

Proc Natl Acad Sci U S A. 2007 Apr 24;104(17):7247-52. Epub 2007 Apr 16.


Functional Equivalence of OspA and OspB, but Not OspC, in Tick Colonization by Borrelia burgdorferi.

Tilly K, Bestor A, Rosa PA.

Infect Immun. 2016 Apr 22;84(5):1565-1573. doi: 10.1128/IAI.00063-16. Print 2016 May.


Modification of Borrelia burgdorferi to overproduce OspA or VlsE alters its infectious behaviour.

Xu Q, McShan K, Liang FT.

Microbiology. 2008 Nov;154(Pt 11):3420-9. doi: 10.1099/mic.0.2008/019737-0.


Two regulatory elements required for enhancing ospA expression in Borrelia burgdorferi grown in vitro but repressing its expression during mammalian infection.

Xu Q, McShan K, Liang FT.

Microbiology. 2010 Jul;156(Pt 7):2194-204. doi: 10.1099/mic.0.036608-0. Epub 2010 Apr 15.


Inhibition of Borrelia burgdorferi-tick interactions in vivo by outer surface protein A antibody.

Pal U, Montgomery RR, Lusitani D, Voet P, Weynants V, Malawista SE, Lobet Y, Fikrig E.

J Immunol. 2001 Jun 15;166(12):7398-403.


Outer surface protein A protects Lyme disease spirochetes from acquired host immunity in the tick vector.

Battisti JM, Bono JL, Rosa PA, Schrumpf ME, Schwan TG, Policastro PF.

Infect Immun. 2008 Nov;76(11):5228-37. doi: 10.1128/IAI.00410-08. Epub 2008 Sep 8.


Infection of mice with lyme disease spirochetes constitutively producing outer surface proteins a and B.

Strother KO, Hodzic E, Barthold SW, de Silva AM.

Infect Immun. 2007 Jun;75(6):2786-94. Epub 2007 Mar 19.


Reciprocal expression of ospA and ospC in single cells of Borrelia burgdorferi.

Srivastava SY, de Silva AM.

J Bacteriol. 2008 May;190(10):3429-33. doi: 10.1128/JB.00085-08. Epub 2008 Mar 21.


Temporal regulation of outer surface proteins of the Lyme-disease spirochaete Borrelia burgdorferi.

Schwan TG.

Biochem Soc Trans. 2003 Feb;31(Pt 1):108-12. Review.


Reductions in human Lyme disease risk due to the effects of oral vaccination on tick-to-mouse and mouse-to-tick transmission.

Voordouw MJ, Tupper H, Önder Ö, Devevey G, Graves CJ, Kemps BD, Brisson D.

Vector Borne Zoonotic Dis. 2013 Apr;13(4):203-14. doi: 10.1089/vbz.2012.1003. Epub 2013 Feb 21.


Antigenic and genetic heterogeneity of Borrelia burgdorferi populations transmitted by ticks.

Ohnishi J, Piesman J, de Silva AM.

Proc Natl Acad Sci U S A. 2001 Jan 16;98(2):670-5.


Protective efficacy of an oral vaccine to reduce carriage of Borrelia burgdorferi (strain N40) in mouse and tick reservoirs.

Scheckelhoff MR, Telford SR, Hu LT.

Vaccine. 2006 Mar 10;24(11):1949-57. Epub 2005 Nov 4.


Borrelia burgdorferi outer surface protein (osp) B expression independent of ospA.

Liang FT, Caimano MJ, Radolf JD, Fikrig E.

Microb Pathog. 2004 Jul;37(1):35-40.


Borrelia burgdorferi OspA is an arthropod-specific transmission-blocking Lyme disease vaccine.

de Silva AM, Telford SR 3rd, Brunet LR, Barthold SW, Fikrig E.

J Exp Med. 1996 Jan 1;183(1):271-5.


Influence of outer surface protein A antibody on Borrelia burgdorferi within feeding ticks.

de Silva AM, Zeidner NS, Zhang Y, Dolan MC, Piesman J, Fikrig E.

Infect Immun. 1999 Jan;67(1):30-5.


Temporal analysis of Borrelia burgdorferi Erp protein expression throughout the mammal-tick infectious cycle.

Miller JC, von Lackum K, Babb K, McAlister JD, Stevenson B.

Infect Immun. 2003 Dec;71(12):6943-52.


Borrelia burgdorferi bba74 is expressed exclusively during tick feeding and is regulated by both arthropod- and mammalian host-specific signals.

Mulay VB, Caimano MJ, Iyer R, Dunham-Ems S, Liveris D, Petzke MM, Schwartz I, Radolf JD.

J Bacteriol. 2009 Apr;191(8):2783-94. doi: 10.1128/JB.01802-08. Epub 2009 Feb 13.

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