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Items: 1 to 20 of 28

1.

Gene expression analysis offers unique advantages to histopathology in liver biopsy evaluations.

Heinloth AN, Boorman GA, Foley JF, Flagler ND, Paules RS.

Toxicol Pathol. 2007 Feb;35(2):276-83. Erratum in: Toxicol Pathol. 2007;35(6):850.

PMID:
17366322
2.

Gene expression profiling of rat livers reveals indicators of potential adverse effects.

Heinloth AN, Irwin RD, Boorman GA, Nettesheim P, Fannin RD, Sieber SO, Snell ML, Tucker CJ, Li L, Travlos GS, Vansant G, Blackshear PE, Tennant RW, Cunningham ML, Paules RS.

Toxicol Sci. 2004 Jul;80(1):193-202. Epub 2004 Apr 14.

PMID:
15084756
3.

Transcriptional profiling of the left and median liver lobes of male f344/n rats following exposure to acetaminophen.

Irwin RD, Parker JS, Lobenhofer EK, Burka LT, Blackshear PE, Vallant MK, Lebetkin EH, Gerken DF, Boorman GA.

Toxicol Pathol. 2005;33(1):111-7.

PMID:
15805062
4.

Phenotypic anchoring of acetaminophen-induced oxidative stress with gene expression profiles in rat liver.

Powell CL, Kosyk O, Ross PK, Schoonhoven R, Boysen G, Swenberg JA, Heinloth AN, Boorman GA, Cunningham ML, Paules RS, Rusyn I.

Toxicol Sci. 2006 Sep;93(1):213-22. Epub 2006 Jun 2.

5.

Mitochondrial protection by the JNK inhibitor leflunomide rescues mice from acetaminophen-induced liver injury.

Latchoumycandane C, Goh CW, Ong MM, Boelsterli UA.

Hepatology. 2007 Feb;45(2):412-21.

PMID:
17366662
6.

Optimal sampling of rat liver tissue for toxicogenomic studies.

Foley JF, Collins JB, Umbach DM, Grissom S, Boorman GA, Heinloth AN.

Toxicol Pathol. 2006;34(6):795-801.

7.

Effects of acetaminophen on hepatic gene expression in mice.

Jeong SY, Lim JS, Park HJ, Cho JW, Rana SV, Yoon S.

Physiol Chem Phys Med NMR. 2006;38(2):77-83.

PMID:
18472468
8.

Protection against acetaminophen toxicity in CYP1A2 and CYP2E1 double-null mice.

Zaher H, Buters JT, Ward JM, Bruno MK, Lucas AM, Stern ST, Cohen SD, Gonzalez FJ.

Toxicol Appl Pharmacol. 1998 Sep;152(1):193-9.

PMID:
9772215
9.

Gene expression profile in liver of differing ages of rats after single oral administration of acetaminophen.

Morishita K, Mizukawa Y, Kasahara T, Okuyama M, Takashima K, Toritsuka N, Miyagishima T, Nagao T, Urushidani T.

J Toxicol Sci. 2006 Dec;31(5):491-507.

10.

Gene interaction network analysis suggests differences between high and low doses of acetaminophen.

Toyoshiba H, Sone H, Yamanaka T, Parham FM, Irwin RD, Boorman GA, Portier CJ.

Toxicol Appl Pharmacol. 2006 Sep 15;215(3):306-16. Epub 2006 May 15.

PMID:
16701773
11.

Influence of acetaminophen and trichloroethylene on liver cytochrome P450-dependent monooxygenase system.

Plewka A, Zielińska-Psuja B, Kowalówka-Zawieja J, Nowaczyk-Dura G, Plewka D, Wiaderkiewicz A, Kamiński M, Orłowski J.

Acta Biochim Pol. 2000;47(4):1129-36.

12.

Effect of acetaminophen administration to rats chronically exposed to depleted uranium.

Guéguen Y, Grandcolas L, Baudelin C, Grison S, Tissandié E, Jourdain JR, Paquet F, Voisin P, Aigueperse J, Gourmelon P, Souidi M.

Toxicology. 2007 Jan 5;229(1-2):62-72. Epub 2006 Oct 17.

PMID:
17126469
13.

Differential gene expression analysis of a known hepatotoxin, N-acetyl-p-amino-phenol (APAP) as compared to its non-toxic analog, N-acetyl-m-amino-phenol (AMAP) in mouse liver.

Priyadarsiny P, Khattar SK, Malik R, Udupa V, Seshaiah A, Rahman S, Shingatgeri VM, Bora RS, Saini KS.

J Toxicol Sci. 2008 May;33(2):163-73.

14.

NTP Toxicology and Carcinogenesis Studies of Coumarin (CAS No. 91-64-5) in F344/N Rats and B6C3F1 Mice (Gavage Studies).

National Toxicology Program .

Natl Toxicol Program Tech Rep Ser. 1993 Sep;422:1-340.

15.

Protective effect of diallyl sulfone against acetaminophen-induced hepatotoxicity in mice.

Lin MC, Wang EJ, Patten C, Lee MJ, Xiao F, Reuhl KR, Yang CS.

J Biochem Toxicol. 1996;11(1):11-20.

PMID:
8806047
16.

Protective effects of garlic and related organosulfur compounds on acetaminophen-induced hepatotoxicity in mice.

Wang EJ, Li Y, Lin M, Chen L, Stein AP, Reuhl KR, Yang CS.

Toxicol Appl Pharmacol. 1996 Jan;136(1):146-54.

PMID:
8560468
17.

Protective effects of diallyl sulfide on acetaminophen-induced toxicities.

Hu JJ, Yoo JS, Lin M, Wang EJ, Yang CS.

Food Chem Toxicol. 1996 Oct;34(10):963-9.

PMID:
9012771
18.

Loss of CYP2E1 and CYP1A2 activity as a function of acetaminophen dose: relation to toxicity.

Snawder JE, Roe AL, Benson RW, Roberts DW.

Biochem Biophys Res Commun. 1994 Aug 30;203(1):532-9. Erratum in: Biochem Biophys Res Commun 1995 Jan 5;206(1):437.

PMID:
8074700
19.

Acetaminophen-induced stimulation of MDR1 expression and activity in rat intestine and in LS 174T human intestinal cell line.

Ghanem CI, Arias A, Novak A, Carpini GD, Villanueva S, Blazquez AG, Marin JJ, Mottino AD, Rubio MC.

Biochem Pharmacol. 2011 Jan 15;81(2):244-50. doi: 10.1016/j.bcp.2010.10.006. Epub 2010 Oct 16.

PMID:
20955690
20.

Innate immune system plays a critical role in determining the progression and severity of acetaminophen hepatotoxicity.

Liu ZX, Govindarajan S, Kaplowitz N.

Gastroenterology. 2004 Dec;127(6):1760-74.

PMID:
15578514

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