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Items: 1 to 20 of 339

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Inhibition of Akt signaling by the lignan matairesinol sensitizes prostate cancer cells to TRAIL-induced apoptosis.

Peuhu E, Rivero-Müller A, Stykki H, Torvaldson E, Holmbom T, Eklund P, Unkila M, Sjöholm R, Eriksson JE.

Oncogene. 2010 Feb 11;29(6):898-908. doi: 10.1038/onc.2009.386. Epub 2009 Nov 23.

PMID:
19935713
5.

Sanguinarine sensitizes human gastric adenocarcinoma AGS cells to TRAIL-mediated apoptosis via down-regulation of AKT and activation of caspase-3.

Choi WY, Jin CY, Han MH, Kim GY, Kim ND, Lee WH, Kim SK, Choi YH.

Anticancer Res. 2009 Nov;29(11):4457-65.

6.

The alkylphospholipid perifosine induces apoptosis of human lung cancer cells requiring inhibition of Akt and activation of the extrinsic apoptotic pathway.

Elrod HA, Lin YD, Yue P, Wang X, Lonial S, Khuri FR, Sun SY.

Mol Cancer Ther. 2007 Jul;6(7):2029-38. Epub 2007 Jun 29.

7.

Heat shock protects HCT116 and H460 cells from TRAIL-induced apoptosis.

Ozören N, El-Deiry W.

Exp Cell Res. 2002 Dec 10;281(2):175-81.

PMID:
12460647
8.

Regulation of Akt by EGF-R inhibitors, a possible mechanism of EGF-R inhibitor-enhanced TRAIL-induced apoptosis.

Park SY, Seol DW.

Biochem Biophys Res Commun. 2002 Jul 12;295(2):515-8.

PMID:
12150980
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10.

Inhibition of cell death by a novel 16.2 kD heat shock protein predominantly via Hsp90 mediated lipid rafts stabilization and Akt activation pathway.

Bellyei S, Szigeti A, Boronkai A, Pozsgai E, Gomori E, Melegh B, Janaky T, Bognar Z, Hocsak E, Sumegi B, Gallyas F Jr.

Apoptosis. 2007 Jan;12(1):97-112.

PMID:
17136496
11.

Sensitization of human K562 leukemic cells to TRAIL-induced apoptosis by inhibiting the DNA-PKcs/Akt-mediated cell survival pathway.

Kim MJ, Kim HB, Bae JH, Lee JW, Park SJ, Kim DW, Park SI, Kang CD, Kim SH.

Biochem Pharmacol. 2009 Sep 15;78(6):573-82. doi: 10.1016/j.bcp.2009.05.016. Epub 2009 May 21.

PMID:
19464267
12.

Role of phosphatidylinositol-3 kinase/Akt pathway in bladder cancer cell apoptosis induced by tumor necrosis factor-related apoptosis-inducing ligand.

Oka N, Tanimoto S, Taue R, Nakatsuji H, Kishimoto T, Izaki H, Fukumori T, Takahashi M, Nishitani M, Kanayama HO.

Cancer Sci. 2006 Oct;97(10):1093-8.

14.

Bid mediates apoptotic synergy between tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and DNA damage.

Broaddus VC, Dansen TB, Abayasiriwardana KS, Wilson SM, Finch AJ, Swigart LB, Hunt AE, Evan GI.

J Biol Chem. 2005 Apr 1;280(13):12486-93. Epub 2004 Dec 22.

15.

Reovirus infection induces apoptosis of TRAIL-resistant gastric cancer cells by down-regulation of Akt activation.

Cho IR, Koh SS, Min HJ, Park EH, Srisuttee R, Jhun BH, Kang CD, Kim M, Johnston RN, Chung YH.

Int J Oncol. 2010 Apr;36(4):1023-30.

PMID:
20198349
16.

TRAIL apoptosis is enhanced by quercetin through Akt dephosphorylation.

Kim YH, Lee YJ.

J Cell Biochem. 2007 Mar 1;100(4):998-1009.

PMID:
17031854
17.

The mitogen-activated protein kinase pathway can inhibit TRAIL-induced apoptosis by prohibiting association of truncated Bid with mitochondria.

Ortiz-Ferrón G, Tait SW, Robledo G, de Vries E, Borst J, López-Rivas A.

Cell Death Differ. 2006 Nov;13(11):1857-65. Epub 2006 Feb 17.

18.

IC101 induces apoptosis by Akt dephosphorylation via an inhibition of heat shock protein 90-ATP binding activity accompanied by preventing the interaction with Akt in L1210 cells.

Fujiwara H, Yamakuni T, Ueno M, Ishizuka M, Shinkawa T, Isobe T, Ohizumi Y.

J Pharmacol Exp Ther. 2004 Sep;310(3):1288-95. Epub 2004 May 25.

19.

Tunicamycin sensitizes human melanoma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by up-regulation of TRAIL-R2 via the unfolded protein response.

Jiang CC, Chen LH, Gillespie S, Kiejda KA, Mhaidat N, Wang YF, Thorne R, Zhang XD, Hersey P.

Cancer Res. 2007 Jun 15;67(12):5880-8.

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