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Items: 1 to 20 of 254

1.

Transplacental carcinogenicity of 3'-azido-3'-deoxythymidine in B6C3F1 mice and F344 rats.

Walker DM, Malarkey DE, Seilkop SK, Ruecker FA, Funk KA, Wolfe MJ, Treanor CP, Foley JF, Hahn FF, Hardisty JF, Walker VE.

Environ Mol Mutagen. 2007 Apr-May;48(3-4):283-98.

PMID:
17358026
2.

Multiorgan transplacental and neonatal carcinogenicity of 3'-azido-3'-deoxythymidine in mice.

Diwan BA, Riggs CW, Logsdon D, Haines DC, Olivero OA, Rice JM, Yuspa SH, Poirier MC, Anderson LM.

Toxicol Appl Pharmacol. 1999 Nov 15;161(1):82-99.

PMID:
10558926
3.

Oxidative DNA damage in fetal tissues after transplacental exposure to 3'-azido-3'-deoxythymidine (AZT).

Bialkowska A, Bialkowski K, Gerschenson M, Diwan BA, Jones AB, Olivero OA, Poirier MC, Anderson LM, Kasprzak KS, Sipowicz MA.

Carcinogenesis. 2000 May;21(5):1059-62.

PMID:
10783333
4.

Genetic alterations in K-ras and p53 cancer genes in lung neoplasms from Swiss (CD-1) male mice exposed transplacentally to AZT.

Hong HH, Dunnick J, Herbert R, Devereux TR, Kim Y, Sills RC.

Environ Mol Mutagen. 2007 Apr-May;48(3-4):299-306. Erratum in: Environ Mol Mutagen. 2007 Jul;48(6):501.

PMID:
16395694
5.

Mitochondrial toxicity in hearts of CD-1 mice following perinatal exposure to AZT, 3TC, or AZT/3TC in combination.

Chan SS, Santos JH, Meyer JN, Mandavilli BS, Cook DL Jr, McCash CL, Kissling GE, Nyska A, Foley JF, van Houten B, Copeland WC, Walker VE, Witt KL, Bishop JB.

Environ Mol Mutagen. 2007 Apr-May;48(3-4):190-200.

PMID:
16395692
6.

Frequency of Hprt mutant lymphocytes and micronucleated erythrocytes in p53-haplodeficient mice treated perinatally with AZT and AZT in combination with 3TC.

Dobrovolsky VN, Shaddock JG, Mittelstaedt RA, Bishop ME, Lewis SM, Lee FW, Aidoo A, Leakey JE, Dunnick JK, Heflich RH.

Environ Mol Mutagen. 2007 Apr-May;48(3-4):270-82.

PMID:
17358030
7.

Transplacental drug transfer and frequency of Tk and Hprt lymphocyte mutants and peripheral blood micronuclei in mice treated transplacentally with zidovudine and lamivudine.

Von Tungeln LS, Williams LD, Doerge DR, Shaddock JG, McGarrity LJ, Morris SM, Mittelstaedt RA, Heflich RH, Beland FA.

Environ Mol Mutagen. 2007 Apr-May;48(3-4):258-69.

PMID:
16850453
8.

Transplacental effects of 3'-azido-2',3'-dideoxythymidine (AZT): tumorigenicity in mice and genotoxicity in mice and monkeys.

Olivero OA, Anderson LM, Diwan BA, Haines DC, Harbaugh SW, Moskal TJ, Jones AB, Rice JM, Riggs CW, Logsdon D, Yuspa SH, Poirier MC.

J Natl Cancer Inst. 1997 Nov 5;89(21):1602-8.

PMID:
9362158
9.

Persistence of mitochondrial toxicity in hearts of female B6C3F1 mice exposed in utero to 3'-azido-3'-deoxythymidine.

Walker DM, Poirier MC, Campen MJ, Cook DL Jr, Divi RL, Nagashima K, Lund AK, Cossey PY, Hahn FF, Walker VE.

Cardiovasc Toxicol. 2004;4(2):133-53.

PMID:
15371630
10.

A transplacental carcinogenicity bioassay in CD-1 mice with zidovudine.

Ayers KM, Torrey CE, Reynolds DJ.

Fundam Appl Toxicol. 1997 Aug;38(2):195-8.

PMID:
9299194
13.

Genotoxicity assessed by the comet and GPA assays following in vitro exposure of human lymphoblastoid cells (H9) or perinatal exposure of mother-child pairs to AZT or AZT-3TC.

Escobar PA, Olivero OA, Wade NA, Abrams EJ, Nesel CJ, Ness RB, Day RD, Day BW, Meng Q, O'Neill JP, Walker DM, Poirier MC, Walker VE, Bigbee WL.

Environ Mol Mutagen. 2007 Apr-May;48(3-4):330-43.

PMID:
17358027
14.

Mutagenicity of zidovudine, lamivudine, and abacavir following in vitro exposure of human lymphoblastoid cells or in utero exposure of CD-1 mice to single agents or drug combinations.

Torres SM, Walker DM, Carter MM, Cook DL Jr, McCash CL, Cordova EM, Olivero OA, Poirier MC, Walker VE.

Environ Mol Mutagen. 2007 Apr-May;48(3-4):224-38.

PMID:
17358033
16.

Incorporation of zidovudine into cord blood DNA of infants and peripheral blood DNA of their HIV-1-positive mothers.

Olivero OA, Shearer GM, Chougnet CA, Kovacs AA, Baker R, Stek AM, Khoury MM, Poirier MC.

Ann N Y Acad Sci. 2000 Nov;918:262-8.

PMID:
11131712
17.

Skin tumorigenesis and Ki-ras and Ha-ras mutations in tumors from adult mice exposed in utero to 3'-azido-2',3'-dideoxythymidine.

Zhang Z, Diwan BA, Anderson LM, Logsdon D, Olivero OA, Haines DC, Rice JM, Yuspa SH, Poirier MC.

Mol Carcinog. 1998 Sep;23(1):45-51.

PMID:
9766437
18.

Perinatal genotoxicity and carcinogenicity of anti-retroviral nucleoside analog drugs.

Poirier MC, Olivero OA, Walker DM, Walker VE.

Toxicol Appl Pharmacol. 2004 Sep 1;199(2):151-61. Review.

PMID:
15313587
19.

Mechanisms of genotoxicity of nucleoside reverse transcriptase inhibitors.

Olivero OA.

Environ Mol Mutagen. 2007 Apr-May;48(3-4):215-23. Review.

PMID:
16395695

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