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Profiling serum biomarkers in patients with COPD: associations with clinical parameters.

Pinto-Plata V, Toso J, Lee K, Park D, Bilello J, Mullerova H, De Souza MM, Vessey R, Celli B.

Thorax. 2007 Jul;62(7):595-601. Epub 2007 Mar 13.


Correlation between serum biomarkers and BODE index in patients with stable COPD.

Liu SF, Chin CH, Wang CC, Lin MC.

Respirology. 2009 Sep;14(7):999-1004. doi: 10.1111/j.1440-1843.2009.01608.x.


Serum cytokine profiling and enrichment analysis reveal the involvement of immunological and inflammatory pathways in stable patients with chronic obstructive pulmonary disease.

Bade G, Khan MA, Srivastava AK, Khare P, Solaiappan KK, Guleria R, Palaniyar N, Talwar A.

Int J Chron Obstruct Pulmon Dis. 2014 Aug 5;9:759-73. doi: 10.2147/COPD.S61347. eCollection 2014.


Systemic biomarkers of neutrophilic inflammation, tissue injury and repair in COPD patients with differing levels of disease severity.

Cockayne DA, Cheng DT, Waschki B, Sridhar S, Ravindran P, Hilton H, Kourteva G, Bitter H, Pillai SG, Visvanathan S, Müller KC, Holz O, Magnussen H, Watz H, Fine JS.

PLoS One. 2012;7(6):e38629. doi: 10.1371/journal.pone.0038629. Epub 2012 Jun 12.


Associations between BODE index and systemic inflammatory biomarkers in COPD.

Gaki E, Kontogianni K, Papaioannou AI, Bakakos P, Gourgoulianis KI, Kostikas K, Alchanatis M, Papiris S, Loukides S.

COPD. 2011 Dec;8(6):408-13. doi: 10.3109/15412555.2011.619599.


Value of procalcitonin, C-reactive protein, and neopterin in exacerbations of chronic obstructive pulmonary disease.

Lacoma A, Prat C, Andreo F, Lores L, Ruiz-Manzano J, Ausina V, Domínguez J.

Int J Chron Obstruct Pulmon Dis. 2011;6:157-69. doi: 10.2147/COPD.S16070. Epub 2011 Feb 28.


Application of a new parameter in the 6-minute walk test for manifold analysis of exercise capacity in patients with COPD.

Ijiri N, Kanazawa H, Yoshikawa T, Hirata K.

Int J Chron Obstruct Pulmon Dis. 2014 Nov 3;9:1235-40. doi: 10.2147/COPD.S71383. eCollection 2014.


Microfibrillar-associated protein 4: a potential biomarker of chronic obstructive pulmonary disease.

Johansson SL, Roberts NB, Schlosser A, Andersen CB, Carlsen J, Wulf-Johansson H, Sækmose SG, Titlestad IL, Tornoe I, Miller B, Tal-Singer R, Holmskov U, Vestbo J, Sorensen GL.

Respir Med. 2014 Sep;108(9):1336-44. doi: 10.1016/j.rmed.2014.06.003. Epub 2014 Jun 20.


Inflammatory biomarkers and exacerbations in chronic obstructive pulmonary disease.

Thomsen M, Ingebrigtsen TS, Marott JL, Dahl M, Lange P, Vestbo J, Nordestgaard BG.

JAMA. 2013 Jun 12;309(22):2353-61. doi: 10.1001/jama.2013.5732.


The BODE index, a multidimensional grading system, reflects impairment of right ventricle functions in patients with chronic obstructive pulmonary disease: a speckle-tracking study.

Gökdeniz T, Kalaycıoğlu E, Boyacı F, Aykan AÇ, Gürsoy MO, Hatem E, Börekçi A, Karabag Y, Altun S.

Respiration. 2014;88(3):223-33. doi: 10.1159/000365222. Epub 2014 Aug 15.


Association between markers of emphysema and more severe chronic obstructive pulmonary disease.

Boschetto P, Quintavalle S, Zeni E, Leprotti S, Potena A, Ballerin L, Papi A, Palladini G, Luisetti M, Annovazzi L, Iadarola P, De Rosa E, Fabbri LM, Mapp CE.

Thorax. 2006 Dec;61(12):1037-42. Epub 2006 Jun 12.


A comparison of three multidimensional indices of COPD severity as predictors of future exacerbations.

Motegi T, Jones RC, Ishii T, Hattori K, Kusunoki Y, Furutate R, Yamada K, Gemma A, Kida K.

Int J Chron Obstruct Pulmon Dis. 2013;8:259-71. doi: 10.2147/COPD.S42769. Epub 2013 May 31.


Six-minute walk distance and dyspnoea scores to assess the course of COPD exacerbation in elderly patients.

Blankenburg T, Guettel A, Busch C, Schuette W.

Clin Respir J. 2013 Jul;7(3):261-7. doi: 10.1111/j.1752-699X.2012.00314.x. Epub 2012 Aug 24.


Increased serum levels of lipocalin-1 and -2 in patients with stable chronic obstructive pulmonary disease.

Wang XR, Li YP, Gao S, Xia W, Gao K, Kong QH, Qi H, Wu L, Zhang J, Qu JM, Bai CX.

Int J Chron Obstruct Pulmon Dis. 2014 May 27;9:543-9. doi: 10.2147/COPD.S62700. eCollection 2014.


Identification of five chronic obstructive pulmonary disease subgroups with different prognoses in the ECLIPSE cohort using cluster analysis.

Rennard SI, Locantore N, Delafont B, Tal-Singer R, Silverman EK, Vestbo J, Miller BE, Bakke P, Celli B, Calverley PM, Coxson H, Crim C, Edwards LD, Lomas DA, MacNee W, Wouters EF, Yates JC, Coca I, Agustí A; Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints.

Ann Am Thorac Soc. 2015 Mar;12(3):303-12. doi: 10.1513/AnnalsATS.201403-125OC.


Matrix metalloproteinase-9 predicts pulmonary status declines in α1-antitrypsin deficiency.

Omachi TA, Eisner MD, Rames A, Markovtsova L, Blanc PD.

Respir Res. 2011 Mar 23;12:35. doi: 10.1186/1465-9921-12-35.


Usefulness of neutrophil to lymphocyte ratio in patients with chronic obstructive pulmonary disease: a prospective observational study.

Lee SJ, Lee HR, Lee TW, Ju S, Lim S, Go SI, You JW, Cho YJ, Lee GW, Jeong YY, Kim HC, Lee JD.

Korean J Intern Med. 2016 Sep;31(5):891-8. doi: 10.3904/kjim.2015.084. Epub 2016 Mar 25.


Changes in the BODE index, exacerbation duration and hospitalisation in a cohort of COPD patients.

Bu XN, Yang T, Thompson MA, Hutchinson AF, Irving LB.

Singapore Med J. 2011 Dec;52(12):894-900.


Circulating vascular endothelial growth factor and systemic inflammatory markers in patients with stable and exacerbated chronic obstructive pulmonary disease.

Valipour A, Schreder M, Wolzt M, Saliba S, Kapiotis S, Eickhoff P, Burghuber OC.

Clin Sci (Lond). 2008 Oct;115(7):225-32. doi: 10.1042/CS20070382.


Biomarkers of systemic inflammation in stable and exacerbation phases of COPD.

Karadag F, Karul AB, Cildag O, Yilmaz M, Ozcan H.

Lung. 2008 Nov-Dec;186(6):403-9. doi: 10.1007/s00408-008-9106-6. Epub 2008 Sep 20.


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