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Items: 1 to 20 of 138

1.

Impaired genome maintenance suppresses the growth hormone--insulin-like growth factor 1 axis in mice with Cockayne syndrome.

van der Pluijm I, Garinis GA, Brandt RM, Gorgels TG, Wijnhoven SW, Diderich KE, de Wit J, Mitchell JR, van Oostrom C, Beems R, Niedernhofer LJ, Velasco S, Friedberg EC, Tanaka K, van Steeg H, Hoeijmakers JH, van der Horst GT.

PLoS Biol. 2007 Jan;5(1):e2. Erratum in: PLoS Biol. 2008 Nov;6(11):e304.

2.

Age-related neuronal degeneration: complementary roles of nucleotide excision repair and transcription-coupled repair in preventing neuropathology.

Jaarsma D, van der Pluijm I, de Waard MC, Haasdijk ED, Brandt R, Vermeij M, Rijksen Y, Maas A, van Steeg H, Hoeijmakers JH, van der Horst GT.

PLoS Genet. 2011 Dec;7(12):e1002405. doi: 10.1371/journal.pgen.1002405.

3.

A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis.

Niedernhofer LJ, Garinis GA, Raams A, Lalai AS, Robinson AR, Appeldoorn E, Odijk H, Oostendorp R, Ahmad A, van Leeuwen W, Theil AF, Vermeulen W, van der Horst GT, Meinecke P, Kleijer WJ, Vijg J, Jaspers NG, Hoeijmakers JH.

Nature. 2006 Dec 21;444(7122):1038-43.

PMID:
17183314
4.

The relationship between benzo[a]pyrene-induced mutagenesis and carcinogenesis in repair-deficient Cockayne syndrome group B mice.

Wijnhoven SW, Kool HJ, van Oostrom CT, Beems RB, Mullenders LH, van Zeeland AA, van der Horst GT, Vrieling H, van Steeg H.

Cancer Res. 2000 Oct 15;60(20):5681-7.

5.

2-AAF-induced tumor development in nucleotide excision repair-deficient mice is associated with a defect in global genome repair but not with transcription coupled repair.

Hoogervorst EM, van Oostrom CT, Beems RB, van Benthem J, van den Berg J, van Kreijl CF, Vos JG, de Vries A, van Steeg H.

DNA Repair (Amst). 2005 Jan 2;4(1):3-9.

PMID:
15533832
6.

Cell type-specific hypersensitivity to oxidative damage in CSB and XPA mice.

de Waard H, de Wit J, Gorgels TG, van den Aardweg G, Andressoo JO, Vermeij M, van Steeg H, Hoeijmakers JH, van der Horst GT.

DNA Repair (Amst). 2003 Jan 2;2(1):13-25.

PMID:
12509265
7.

Differential ultraviolet-B-induced immunomodulation in XPA, XPC, and CSB DNA repair-deficient mice.

Boonstra A, van Oudenaren A, Baert M, van Steeg H, Leenen PJ, van der Horst GT, Hoeijmakers JH, Savelkoul HF, Garssen J.

J Invest Dermatol. 2001 Jul;117(1):141-6.

8.

Early postnatal ataxia and abnormal cerebellar development in mice lacking Xeroderma pigmentosum Group A and Cockayne syndrome Group B DNA repair genes.

Murai M, Enokido Y, Inamura N, Yoshino M, Nakatsu Y, van der Horst GT, Hoeijmakers JH, Tanaka K, Hatanaka H.

Proc Natl Acad Sci U S A. 2001 Nov 6;98(23):13379-84.

9.

Retinal degeneration and ionizing radiation hypersensitivity in a mouse model for Cockayne syndrome.

Gorgels TG, van der Pluijm I, Brandt RM, Garinis GA, van Steeg H, van den Aardweg G, Jansen GH, Ruijter JM, Bergen AA, van Norren D, Hoeijmakers JH, van der Horst GT.

Mol Cell Biol. 2007 Feb;27(4):1433-41.

10.

Cockayne syndrome group B (CSB) protein: at the crossroads of transcriptional networks.

Vélez-Cruz R, Egly JM.

Mech Ageing Dev. 2013 May-Jun;134(5-6):234-42. doi: 10.1016/j.mad.2013.03.004. Review.

PMID:
23562425
11.

Cell-type-specific consequences of nucleotide excision repair deficiencies: Embryonic stem cells versus fibroblasts.

de Waard H, Sonneveld E, de Wit J, Esveldt-van Lange R, Hoeijmakers JH, Vrieling H, van der Horst GT.

DNA Repair (Amst). 2008 Oct 1;7(10):1659-69. doi: 10.1016/j.dnarep.2008.06.009.

PMID:
18634906
12.

Adaptive stress response in segmental progeria resembles long-lived dwarfism and calorie restriction in mice.

van de Ven M, Andressoo JO, Holcomb VB, von Lindern M, Jong WM, De Zeeuw CI, Suh Y, Hasty P, Hoeijmakers JH, van der Horst GT, Mitchell JR.

PLoS Genet. 2006 Dec 15;2(12):e192. Erratum in: PLoS Genet. 2008 Oct;4(10).doi: 10.1371/annotation/31502636-9bdf-4cb1-b995-4a30a607e316..

13.

Age to survive: DNA damage and aging.

Schumacher B, Garinis GA, Hoeijmakers JH.

Trends Genet. 2008 Feb;24(2):77-85. doi: 10.1016/j.tig.2007.11.004. Review.

PMID:
18192065
14.

Intestinal toxicity and carcinogenic potential of the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in DNA repair deficient XPA-/- mice.

Klein JC, Beems RB, Zwart PE, Hamzink M, Zomer G, van Steeg H, van Kreijl CF.

Carcinogenesis. 2001 Apr;22(4):619-26.

15.

Suppression of UV carcinogenesis by difluoromethylornithine in nucleotide excision repair-deficient Xpa knockout mice.

Rebel H, van Steeg H, Beems RB, Schouten R, de Gruijl FR, Terleth C.

Cancer Res. 2002 Mar 1;62(5):1338-42.

16.

Delay of DNA-adduct repair and severe toxicity in xeroderma pigmentosum group A gene (XPA) deficient mice treated with 2-amino-1-methyl-6-phenyl-imidazo [4,5-b] pyridine (PhIP).

Imaida K, Ogawa K, Takahashi S, Ito T, Yamaguchi T, Totsuka Y, Wakabayashi K, Tanaka K, Ito N, Shirai T.

Cancer Lett. 2000 Mar 13;150(1):63-9.

PMID:
10755388
17.

Different effects of CSA and CSB deficiency on sensitivity to oxidative DNA damage.

de Waard H, de Wit J, Andressoo JO, van Oostrom CT, Riis B, Weimann A, Poulsen HE, van Steeg H, Hoeijmakers JH, van der Horst GT.

Mol Cell Biol. 2004 Sep;24(18):7941-8.

18.

The cross talk between pathways in the repair of 8-oxo-7,8-dihydroguanine in mouse and human cells.

Parlanti E, D'Errico M, Degan P, Calcagnile A, Zijno A, van der Pluijm I, van der Horst GT, Biard DS, Dogliotti E.

Free Radic Biol Med. 2012 Dec 1;53(11):2171-7. doi: 10.1016/j.freeradbiomed.2012.08.593.

PMID:
23010470
19.

Premature aging in mice deficient in DNA repair and transcription.

de Boer J, Andressoo JO, de Wit J, Huijmans J, Beems RB, van Steeg H, Weeda G, van der Horst GT, van Leeuwen W, Themmen AP, Meradji M, Hoeijmakers JH.

Science. 2002 May 17;296(5571):1276-9.

20.

Differential role of transcription-coupled repair in UVB-induced G2 arrest and apoptosis in mouse epidermis.

van Oosten M, Rebel H, Friedberg EC, van Steeg H, van der Horst GT, van Kranen HJ, Westerman A, van Zeeland AA, Mullenders LH, de Gruijl FR.

Proc Natl Acad Sci U S A. 2000 Oct 10;97(21):11268-73.

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