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Items: 1 to 20 of 91

1.

A host lipase detoxifies bacterial lipopolysaccharides in the liver and spleen.

Shao B, Lu M, Katz SC, Varley AW, Hardwick J, Rogers TE, Ojogun N, Rockey DC, Dematteo RP, Munford RS.

J Biol Chem. 2007 May 4;282(18):13726-35. Epub 2007 Feb 24.

2.

Adenovirus-mediated transfer of a gene encoding acyloxyacyl hydrolase (AOAH) into mice increases tissue and plasma AOAH activity.

Coulthard MG, Swindle J, Munford RS, Gerard RD, Meidell RS.

Infect Immun. 1996 May;64(5):1510-5.

3.

Prolonged hepatomegaly in mice that cannot inactivate bacterial endotoxin.

Shao B, Kitchens RL, Munford RS, Rogers TE, Rockey DC, Varley AW.

Hepatology. 2011 Sep 2;54(3):1051-62. doi: 10.1002/hep.24488. Epub 2011 Jul 27.

4.

Endotoxin-binding proteins modulate the susceptibility of bacterial endotoxin to deacylation by acyloxyacyl hydrolase.

Gioannini TL, Teghanemt A, Zhang D, Prohinar P, Levis EN, Munford RS, Weiss JP.

J Biol Chem. 2007 Mar 16;282(11):7877-84. Epub 2007 Jan 16.

5.

Overproduction of acyloxyacyl hydrolase by macrophages and dendritic cells prevents prolonged reactions to bacterial lipopolysaccharide in vivo.

Ojogun N, Kuang TY, Shao B, Greaves DR, Munford RS, Varley AW.

J Infect Dis. 2009 Dec 1;200(11):1685-93. doi: 10.1086/646616.

6.

Identification of acyloxyacyl hydrolase, a lipopolysaccharide-detoxifying enzyme, in the murine urinary tract.

Feulner JA, Lu M, Shelton JM, Zhang M, Richardson JA, Munford RS.

Infect Immun. 2004 Jun;72(6):3171-8.

7.

Host inactivation of bacterial lipopolysaccharide prevents prolonged tolerance following gram-negative bacterial infection.

Lu M, Varley AW, Ohta S, Hardwick J, Munford RS.

Cell Host Microbe. 2008 Sep 11;4(3):293-302. doi: 10.1016/j.chom.2008.06.009.

8.

Altered inactivation of commensal LPS due to acyloxyacyl hydrolase deficiency in colonic dendritic cells impairs mucosal Th17 immunity.

Janelsins BM, Lu M, Datta SK.

Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):373-8. doi: 10.1073/pnas.1311987111. Epub 2013 Dec 16.

9.

Hepatic uptake and deacylation of the LPS in bloodborne LPS-lipoprotein complexes.

Shao B, Munford RS, Kitchens R, Varley AW.

Innate Immun. 2012 Dec;18(6):825-33. doi: 10.1177/1753425912442431. Epub 2012 Mar 22.

10.

Lipopolysaccharide deacylation by an endogenous lipase controls innate antibody responses to Gram-negative bacteria.

Lu M, Zhang M, Takashima A, Weiss J, Apicella MA, Li XH, Yuan D, Munford RS.

Nat Immunol. 2005 Oct;6(10):989-94. Epub 2005 Sep 11.

PMID:
16155573
12.

Expression and characterization of recombinant human acyloxyacyl hydrolase, a leukocyte enzyme that deacylates bacterial lipopolysaccharides.

Hagen FS, Grant FJ, Kuijper JL, Slaughter CA, Moomaw CR, Orth K, O'Hara PJ, Munford RS.

Biochemistry. 1991 Aug 27;30(34):8415-23.

PMID:
1883828
13.

Bovine blood neutrophil acyloxyacyl hydrolase (AOAH) activity during endotoxin and coliform mastitis.

Mehrzad J, Dosogne H, De Spiegeleer B, Duchateau L, Burvenich C.

Vet Res. 2007 Sep-Oct;38(5):655-68. Epub 2007 Jun 23.

16.

Acyloxyacyl hydrolase promotes the resolution of lipopolysaccharide-induced acute lung injury.

Zou B, Jiang W, Han H, Li J, Mao W, Tang Z, Yang Q, Qian G, Qian J, Zeng W, Gu J, Chu T, Zhu N, Zhang W, Yan D, He R, Chu Y, Lu M.

PLoS Pathog. 2017 Jun 16;13(6):e1006436. doi: 10.1371/journal.ppat.1006436. eCollection 2017 Jun.

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20.

Stimulus-dependent deacylation of bacterial lipopolysaccharide by dendritic cells.

Lu M, Zhang M, Kitchens RL, Fosmire S, Takashima A, Munford RS.

J Exp Med. 2003 Jun 16;197(12):1745-54.

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