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Items: 1 to 20 of 114

1.

Interactions of Kid-Kis toxin-antitoxin complexes with the parD operator-promoter region of plasmid R1 are piloted by the Kis antitoxin and tuned by the stoichiometry of Kid-Kis oligomers.

Monti MC, Hernández-Arriaga AM, Kamphuis MB, López-Villarejo J, Heck AJ, Boelens R, Díaz-Orejas R, van den Heuvel RH.

Nucleic Acids Res. 2007;35(5):1737-49. Epub 2007 Feb 21.

2.

Interactions between the toxin Kid of the bacterial parD system and the antitoxins Kis and MazE.

Kamphuis MB, Monti MC, van den Heuvel RH, Santos-Sierra S, Folkers GE, Lemonnier M, Díaz-Orejas R, Heck AJ, Boelens R.

Proteins. 2007 Apr 1;67(1):219-31.

PMID:
17206710
3.

Cleavage of the antitoxin of the parD toxin-antitoxin system is determined by the ClpAP protease and is modulated by the relative ratio of the toxin and the antitoxin.

Diago-Navarro E, Hernández-Arriaga AM, Kubik S, Konieczny I, Díaz-Orejas R.

Plasmid. 2013 Jul;70(1):78-85. doi: 10.1016/j.plasmid.2013.01.010. Epub 2013 Feb 15.

PMID:
23419648
4.

Genetic identification of two functional regions in the antitoxin of the parD killer system of plasmid R1.

Santos-Sierra S, Pardo-Abarrio C, Giraldo R, Díaz-Orejas R.

FEMS Microbiol Lett. 2002 Jan 2;206(1):115-9.

5.
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7.

RNase/anti-RNase activities of the bacterial parD toxin-antitoxin system.

Muñoz-Gómez AJ, Lemonnier M, Santos-Sierra S, Berzal-Herranz A, Díaz-Orejas R.

J Bacteriol. 2005 May;187(9):3151-7.

8.

Kis antitoxin couples plasmid R1 replication and parD (kis,kid) maintenance modules.

López-Villarejo J, Diago-Navarro E, Hernández-Arriaga AM, Díaz-Orejas R.

Plasmid. 2012 Mar;67(2):118-27. doi: 10.1016/j.plasmid.2011.12.015. Epub 2012 Jan 8.

PMID:
22244926
9.

Identification of residues of the kid toxin involved in autoregulation of the parD system.

Lemonnier M, Santos-Sierra S, Pardo-Abarrio C, Díaz-Orejas R.

J Bacteriol. 2004 Jan;186(1):240-3.

10.

Structure and function of bacterial kid-kis and related toxin-antitoxin systems.

Kamphuis MB, Monti MC, van den Heuvel RH, López-Villarejo J, Díaz-Orejas R, Boelens R.

Protein Pept Lett. 2007;14(2):113-24. Review.

PMID:
17305597
11.

Plasmid RK2 toxin protein ParE: purification and interaction with the ParD antitoxin protein.

Johnson EP, Strom AR, Helinski DR.

J Bacteriol. 1996 Mar;178(5):1420-9.

12.

Kid, a small protein of the parD stability system of plasmid R1, is an inhibitor of DNA replication acting at the initiation of DNA synthesis.

Ruiz-Echevarría MJ, Giménez-Gallego G, Sabariegos-Jareño R, Díaz-Orejas R.

J Mol Biol. 1995 Apr 7;247(4):568-77.

PMID:
7723014
13.

Model for RNA binding and the catalytic site of the RNase Kid of the bacterial parD toxin-antitoxin system.

Kamphuis MB, Bonvin AM, Monti MC, Lemonnier M, Muñoz-Gómez A, van den Heuvel RH, Díaz-Orejas R, Boelens R.

J Mol Biol. 2006 Mar 17;357(1):115-26. Epub 2005 Dec 27.

PMID:
16413033
14.

A common origin for the bacterial toxin-antitoxin systems parD and ccd, suggested by analyses of toxin/target and toxin/antitoxin interactions.

Smith AB, López-Villarejo J, Diago-Navarro E, Mitchenall LA, Barendregt A, Heck AJ, Lemonnier M, Maxwell A, Díaz-Orejas R.

PLoS One. 2012;7(9):e46499. doi: 10.1371/journal.pone.0046499. Epub 2012 Sep 28.

15.

Crystallization and preliminary X-ray crystallographic studies on the parD-encoded protein Kid from Escherichia coli plasmid R1.

Hargreaves D, Giraldo R, Santos-Sierra S, Boelens R, Rice DW, Díaz Orejas R, Rafferty JB.

Acta Crystallogr D Biol Crystallogr. 2002 Feb;58(Pt 2):355-8. Epub 2002 Jan 24.

PMID:
11807276
16.
17.

Toxin Kid uncouples DNA replication and cell division to enforce retention of plasmid R1 in Escherichia coli cells.

Pimentel B, Nair R, Bermejo-Rodríguez C, Preston MA, Agu CA, Wang X, Bernal JA, Sherratt DJ, de la Cueva-Méndez G.

Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2734-9. doi: 10.1073/pnas.1308241111. Epub 2014 Jan 21.

18.

Coupling between the basic replicon and the Kis-Kid maintenance system of plasmid R1: modulation by Kis antitoxin levels and involvement in control of plasmid replication.

López-Villarejo J, Lobato-Márquez D, Díaz-Orejas R.

Toxins (Basel). 2015 Feb 5;7(2):478-92. doi: 10.3390/toxins7020478.

19.

Non-cytotoxic variants of the Kid protein that retain their auto-regulatory activity.

Santos-Sierra S, Lemonnier M, Nuñez B, Hargreaves D, Rafferty J, Giraldo R, Andreu JM, Díaz-Orejas R.

Plasmid. 2003 Sep;50(2):120-30.

PMID:
12932738
20.

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