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Items: 1 to 20 of 116

1.

Pin1 in Alzheimer's disease: multiple substrates, one regulatory mechanism?

Balastik M, Lim J, Pastorino L, Lu KP.

Biochim Biophys Acta. 2007 Apr;1772(4):422-9. Epub 2007 Jan 23. Review.

2.

The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-beta production.

Pastorino L, Sun A, Lu PJ, Zhou XZ, Balastik M, Finn G, Wulf G, Lim J, Li SH, Li X, Xia W, Nicholson LK, Lu KP.

Nature. 2006 Mar 23;440(7083):528-34. Erratum in: Nature. 2007 Mar 15;446(7133):342.

PMID:
16554819
3.

Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration.

Liou YC, Sun A, Ryo A, Zhou XZ, Yu ZX, Huang HK, Uchida T, Bronson R, Bing G, Li X, Hunter T, Lu KP.

Nature. 2003 Jul 31;424(6948):556-61.

PMID:
12891359
4.

Granular expression of prolyl-peptidyl isomerase PIN1 is a constant and specific feature of Alzheimer's disease pathology and is independent of tau, Aβ and TDP-43 pathology.

Dakson A, Yokota O, Esiri M, Bigio EH, Horan M, Pendleton N, Richardson A, Neary D, Snowden JS, Robinson A, Davidson YS, Mann DM.

Acta Neuropathol. 2011 May;121(5):635-49. doi: 10.1007/s00401-011-0798-y. Epub 2011 Jan 18.

5.

DNA sequence variations in the prolyl isomerase Pin1 gene and Alzheimer's disease.

Poli M, Gatta LB, Dominici R, Lovati C, Mariani C, Albertini A, Finazzi D.

Neurosci Lett. 2005 Dec 2;389(2):66-70.

PMID:
16095818
6.
7.

Pin1 contribution to Alzheimer's disease: transcriptional and epigenetic mechanisms in patients with late-onset Alzheimer's disease.

Arosio B, Bulbarelli A, Bastias Candia S, Lonati E, Mastronardi L, Romualdi P, Candeletti S, Gussago C, Galimberti D, Scarpini E, Dell'Osso B, Altamura C, MacCarrone M, Bergamaschini L, D'Addario C, Mari D.

Neurodegener Dis. 2012;10(1-4):207-11. doi: 10.1159/000333799. Epub 2012 Jan 17.

PMID:
22261503
8.

Oxidative modification and down-regulation of Pin1 in Alzheimer's disease hippocampus: A redox proteomics analysis.

Sultana R, Boyd-Kimball D, Poon HF, Cai J, Pierce WM, Klein JB, Markesbery WR, Zhou XZ, Lu KP, Butterfield DA.

Neurobiol Aging. 2006 Jul;27(7):918-25. Epub 2005 Jun 13.

PMID:
15950321
9.
10.

Phosphorylation-dependent prolyl isomerization: a novel signaling regulatory mechanism.

Zhou XZ, Lu PJ, Wulf G, Lu KP.

Cell Mol Life Sci. 1999 Nov 30;56(9-10):788-806. Review.

PMID:
11212339
11.

Pin1 promotes degradation of Smad proteins and their interaction with phosphorylated tau in Alzheimer's disease.

Ueberham U, Rohn S, Ueberham E, Wodischeck S, Hilbrich I, Holzer M, Brückner MK, Gruschka H, Arendt T.

Neuropathol Appl Neurobiol. 2014 Dec;40(7):815-32. doi: 10.1111/nan.12163.

PMID:
24964035
12.

Pin1 in Alzheimer's disease.

Butterfield DA, Abdul HM, Opii W, Newman SF, Joshi G, Ansari MA, Sultana R.

J Neurochem. 2006 Sep;98(6):1697-706. Review.

13.

Pin1: a new outlook in Alzheimer's disease.

Lonati E, Masserini M, Bulbarelli A.

Curr Alzheimer Res. 2011 Sep;8(6):615-22. Review.

PMID:
21605045
14.

Association studies between common variants in prolyl isomerase Pin1 and the risk for late-onset Alzheimer's disease.

Nowotny P, Bertelsen S, Hinrichs AL, Kauwe JS, Mayo K, Jacquart S, Morris JC, Goate A.

Neurosci Lett. 2007 May 23;419(1):15-7. Epub 2007 Apr 13.

15.

Prolyl isomerase, Pin1: new findings of post-translational modifications and physiological substrates in cancer, asthma and Alzheimer's disease.

Takahashi K, Uchida C, Shin RW, Shimazaki K, Uchida T.

Cell Mol Life Sci. 2008 Feb;65(3):359-75. Review.

PMID:
17965833
17.

A PIN1 polymorphism that prevents its suppression by AP4 associates with delayed onset of Alzheimer's disease.

Ma SL, Tang NL, Tam CW, Lui VW, Lam LC, Chiu HF, Driver JA, Pastorino L, Lu KP.

Neurobiol Aging. 2012 Apr;33(4):804-13. doi: 10.1016/j.neurobiolaging.2010.05.018. Epub 2010 Jun 30.

18.

Isomerase Pin1 stimulates dephosphorylation of tau protein at cyclin-dependent kinase (Cdk5)-dependent Alzheimer phosphorylation sites.

Kimura T, Tsutsumi K, Taoka M, Saito T, Masuda-Suzukake M, Ishiguro K, Plattner F, Uchida T, Isobe T, Hasegawa M, Hisanaga S.

J Biol Chem. 2013 Mar 15;288(11):7968-77. doi: 10.1074/jbc.M112.433326. Epub 2013 Jan 28.

19.

Inverse association of Pin1 and tau accumulation in Alzheimer's disease hippocampus.

Holzer M, Gärtner U, Stöbe A, Härtig W, Gruschka H, Brückner MK, Arendt T.

Acta Neuropathol. 2002 Nov;104(5):471-81. Epub 2002 Jul 3.

PMID:
12410395
20.

Pin1 colocalization with phosphorylated tau in Alzheimer's disease and other tauopathies.

Ramakrishnan P, Dickson DW, Davies P.

Neurobiol Dis. 2003 Nov;14(2):251-64.

PMID:
14572447

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