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Inhibition of G alpha i2 activation by G alpha i3 in CXCR3-mediated signaling.

Thompson BD, Jin Y, Wu KH, Colvin RA, Luster AD, Birnbaumer L, Wu MX.

J Biol Chem. 2007 Mar 30;282(13):9547-55. Epub 2007 Feb 8.


Gαi2- and Gαi3-specific regulation of voltage-dependent L-type calcium channels in cardiomyocytes.

Dizayee S, Kaestner S, Kuck F, Hein P, Klein C, Piekorz RP, Meszaros J, Matthes J, Bjrnbaumer L, Nürnberg B, Herzig S.

PLoS One. 2011;6(9):e24979. doi: 10.1371/journal.pone.0024979. Epub 2011 Sep 26. Erratum in: PLoS One. 2013;8(8). doi:10.1371/annotation/7be097c0-9075-41ae-91e9-d2209de952cc. Bjrnbaumer, Lutz [added].


Pharmacological characterization of CXC chemokine receptor 3 ligands and a small molecule antagonist.

Heise CE, Pahuja A, Hudson SC, Mistry MS, Putnam AL, Gross MM, Gottlieb PA, Wade WS, Kiankarimi M, Schwarz D, Crowe P, Zlotnik A, Alleva DG.

J Pharmacol Exp Ther. 2005 Jun;313(3):1263-71. Epub 2005 Mar 10.


CXCR3 internalization following T cell-endothelial cell contact: preferential role of IFN-inducible T cell alpha chemoattractant (CXCL11).

Sauty A, Colvin RA, Wagner L, Rochat S, Spertini F, Luster AD.

J Immunol. 2001 Dec 15;167(12):7084-93.


Cross reactivity of three T cell attracting murine chemokines stimulating the CXC chemokine receptor CXCR3 and their induction in cultured cells and during allograft rejection.

Meyer M, Hensbergen PJ, van der Raaij-Helmer EM, Brandacher G, Margreiter R, Heufler C, Koch F, Narumi S, Werner ER, Colvin R, Luster AD, Tensen CP, Werner-Felmayer G.

Eur J Immunol. 2001 Aug;31(8):2521-7.


CCR3 functional responses are regulated by both CXCR3 and its ligands CXCL9, CXCL10 and CXCL11.

Xanthou G, Duchesnes CE, Williams TJ, Pease JE.

Eur J Immunol. 2003 Aug;33(8):2241-50.


Label-free impedance responses of endogenous and synthetic chemokine receptor CXCR3 agonists correlate with Gi-protein pathway activation.

Watts AO, Scholten DJ, Heitman LH, Vischer HF, Leurs R.

Biochem Biophys Res Commun. 2012 Mar 9;419(2):412-8. doi: 10.1016/j.bbrc.2012.02.036. Epub 2012 Feb 13.


Critical role for CXCR3 chemokine biology in the pathogenesis of bronchiolitis obliterans syndrome.

Belperio JA, Keane MP, Burdick MD, Lynch JP 3rd, Xue YY, Li K, Ross DJ, Strieter RM.

J Immunol. 2002 Jul 15;169(2):1037-49.


Differentiation of human T cells alters their repertoire of G protein alpha-subunits.

Foley JF, Singh SP, Cantu M, Chen L, Zhang HH, Farber JM.

J Biol Chem. 2010 Nov 12;285(46):35537-50. doi: 10.1074/jbc.M110.128033. Epub 2010 Sep 9.


CXCR3-mediated chemotaxis of human T cells is regulated by a Gi- and phospholipase C-dependent pathway and not via activation of MEK/p44/p42 MAPK nor Akt/PI-3 kinase.

Smit MJ, Verdijk P, van der Raaij-Helmer EM, Navis M, Hensbergen PJ, Leurs R, Tensen CP.

Blood. 2003 Sep 15;102(6):1959-65. Epub 2003 May 15.


Intracellular domains of CXCR3 that mediate CXCL9, CXCL10, and CXCL11 function.

Colvin RA, Campanella GS, Sun J, Luster AD.

J Biol Chem. 2004 Jul 16;279(29):30219-27. Epub 2004 May 17.


Galpha(i2) but not Galpha(i3) is required for muscarinic inhibition of contractility and calcium currents in adult cardiomyocytes.

Nagata K, Ye C, Jain M, Milstone DS, Liao R, Mortensen RM.

Circ Res. 2000 Nov 10;87(10):903-9.


Gαi2 is the essential Gαi protein in immune complex-induced lung disease.

Wiege K, Ali SR, Gewecke B, Novakovic A, Konrad FM, Pexa K, Beer-Hammer S, Reutershan J, Piekorz RP, Schmidt RE, Nürnberg B, Gessner JE.

J Immunol. 2013 Jan 1;190(1):324-33. doi: 10.4049/jimmunol.1201398. Epub 2012 Dec 5.


Defective macrophage migration in Gαi2- but not Gαi3-deficient mice.

Wiege K, Le DD, Syed SN, Ali SR, Novakovic A, Beer-Hammer S, Piekorz RP, Schmidt RE, Nürnberg B, Gessner JE.

J Immunol. 2012 Jul 15;189(2):980-7. doi: 10.4049/jimmunol.1200891. Epub 2012 Jun 15.

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