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Items: 1 to 20 of 168

1.

FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress.

Tothova Z, Kollipara R, Huntly BJ, Lee BH, Castrillon DH, Cullen DE, McDowell EP, Lazo-Kallanian S, Williams IR, Sears C, Armstrong SA, Passegué E, DePinho RA, Gilliland DG.

Cell. 2007 Jan 26;128(2):325-39.

3.

Expanded granulocyte/monocyte compartment in myeloid-specific triple FoxO knockout increases oxidative stress and accelerates atherosclerosis in mice.

Tsuchiya K, Westerterp M, Murphy AJ, Subramanian V, Ferrante AW Jr, Tall AR, Accili D.

Circ Res. 2013 Mar 29;112(7):992-1003. doi: 10.1161/CIRCRESAHA.112.300749. Epub 2013 Feb 18.

4.

FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis.

Paik JH, Kollipara R, Chu G, Ji H, Xiao Y, Ding Z, Miao L, Tothova Z, Horner JW, Carrasco DR, Jiang S, Gilliland DG, Chin L, Wong WH, Castrillon DH, DePinho RA.

Cell. 2007 Jan 26;128(2):309-23.

5.

FOXO3 Transcription Factor Is Essential for Protecting Hematopoietic Stem and Progenitor Cells from Oxidative DNA Damage.

Bigarella CL, Li J, Rimmelé P, Liang R, Sobol RW, Ghaffari S.

J Biol Chem. 2017 Feb 17;292(7):3005-3015. doi: 10.1074/jbc.M116.769455. Epub 2016 Dec 19.

PMID:
27994057
6.

Connexin-43 prevents hematopoietic stem cell senescence through transfer of reactive oxygen species to bone marrow stromal cells.

Taniguchi Ishikawa E, Gonzalez-Nieto D, Ghiaur G, Dunn SK, Ficker AM, Murali B, Madhu M, Gutstein DE, Fishman GI, Barrio LC, Cancelas JA.

Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):9071-6. doi: 10.1073/pnas.1120358109. Epub 2012 May 18.

7.

Mitochondrial metabolism in hematopoietic stem cells requires functional FOXO3.

Rimmelé P, Liang R, Bigarella CL, Kocabas F, Xie J, Serasinghe MN, Chipuk J, Sadek H, Zhang CC, Ghaffari S.

EMBO Rep. 2015 Sep;16(9):1164-76. doi: 10.15252/embr.201439704. Epub 2015 Jul 24.

8.

Flk2/Flt3 promotes both myeloid and lymphoid development by expanding non-self-renewing multipotent hematopoietic progenitor cells.

Beaudin AE, Boyer SW, Forsberg EC.

Exp Hematol. 2014 Mar;42(3):218-229.e4. doi: 10.1016/j.exphem.2013.11.013. Epub 2013 Dec 11.

9.

The MicroRNA-132 and MicroRNA-212 Cluster Regulates Hematopoietic Stem Cell Maintenance and Survival with Age by Buffering FOXO3 Expression.

Mehta A, Zhao JL, Sinha N, Marinov GK, Mann M, Kowalczyk MS, Galimidi RP, Du X, Erikci E, Regev A, Chowdhury K, Baltimore D.

Immunity. 2015 Jun 16;42(6):1021-32. doi: 10.1016/j.immuni.2015.05.017.

10.

Differentiation of human adipose-derived stem cells into fat involves reactive oxygen species and Forkhead box O1 mediated upregulation of antioxidant enzymes.

Higuchi M, Dusting GJ, Peshavariya H, Jiang F, Hsiao ST, Chan EC, Liu GS.

Stem Cells Dev. 2013 Mar 15;22(6):878-88. doi: 10.1089/scd.2012.0306. Epub 2012 Nov 12.

11.

Evidence for AKT-independent regulation of FOXO1 and FOXO3 in haematopoietic stem and progenitor cells.

Liang R, Rimmelé P, Bigarella CL, Yalcin S, Ghaffari S.

Cell Cycle. 2016;15(6):861-7. doi: 10.1080/15384101.2015.1123355.

12.

FOXOs attenuate bone formation by suppressing Wnt signaling.

Iyer S, Ambrogini E, Bartell SM, Han L, Roberson PK, de Cabo R, Jilka RL, Weinstein RS, O'Brien CA, Manolagas SC, Almeida M.

J Clin Invest. 2013 Aug;123(8):3409-19. doi: 10.1172/JCI68049. Epub 2013 Jul 15.

13.

FoxO transcription factors and stem cell homeostasis: insights from the hematopoietic system.

Tothova Z, Gilliland DG.

Cell Stem Cell. 2007 Aug 16;1(2):140-52. doi: 10.1016/j.stem.2007.07.017. Review.

14.

Myeloid or lymphoid promiscuity as a critical step in hematopoietic lineage commitment.

Miyamoto T, Iwasaki H, Reizis B, Ye M, Graf T, Weissman IL, Akashi K.

Dev Cell. 2002 Jul;3(1):137-47.

15.

FoxO-mediated defense against oxidative stress in osteoblasts is indispensable for skeletal homeostasis in mice.

Ambrogini E, Almeida M, Martin-Millan M, Paik JH, Depinho RA, Han L, Goellner J, Weinstein RS, Jilka RL, O'Brien CA, Manolagas SC.

Cell Metab. 2010 Feb 3;11(2):136-46. doi: 10.1016/j.cmet.2009.12.009.

16.

Should I stay or should I go: beta-catenin decides under stress.

Hoogeboom D, Burgering BM.

Biochim Biophys Acta. 2009 Dec;1796(2):63-74. doi: 10.1016/j.bbcan.2009.02.002. Epub 2009 Mar 4. Review.

PMID:
19268509
17.

Bone marrow connexin-43 expression is critical for hematopoietic regeneration after chemotherapy.

Presley CA, Lee AW, Kastl B, Igbinosa I, Yamada Y, Fishman GI, Gutstein DE, Cancelas JA.

Cell Commun Adhes. 2005 Jul-Dec;12(5-6):307-17.

PMID:
16531325
18.

FoxO transcription factors support oxidative stress resistance in human chondrocytes.

Akasaki Y, Alvarez-Garcia O, Saito M, Caramés B, Iwamoto Y, Lotz MK.

Arthritis Rheumatol. 2014 Dec;66(12):3349-58. doi: 10.1002/art.38868.

19.

AKT1 and AKT2 maintain hematopoietic stem cell function by regulating reactive oxygen species.

Juntilla MM, Patil VD, Calamito M, Joshi RP, Birnbaum MJ, Koretzky GA.

Blood. 2010 May 20;115(20):4030-8. doi: 10.1182/blood-2009-09-241000. Epub 2010 Mar 30.

20.

Stem cell leukemia protein directs hematopoietic stem cell fate.

Kunisato A, Chiba S, Saito T, Kumano K, Nakagami-Yamaguchi E, Yamaguchi T, Hirai H.

Blood. 2004 May 1;103(9):3336-41. Epub 2004 Jan 15.

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