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Items: 1 to 20 of 189

1.
2.

Signal regulatory protein alpha negatively regulates both TLR3 and cytoplasmic pathways in type I interferon induction.

Dong LW, Kong XN, Yan HX, Yu LX, Chen L, Yang W, Liu Q, Huang DD, Wu MC, Wang HY.

Mol Immunol. 2008 Jun;45(11):3025-35. doi: 10.1016/j.molimm.2008.03.012. Epub 2008 May 8.

PMID:
18471880
3.

Interferon-regulatory-factor 1 controls Toll-like receptor 9-mediated IFN-beta production in myeloid dendritic cells.

Schmitz F, Heit A, Guggemoos S, Krug A, Mages J, Schiemann M, Adler H, Drexler I, Haas T, Lang R, Wagner H.

Eur J Immunol. 2007 Feb;37(2):315-27.

4.

Double-stranded RNA induces pancreatic beta-cell apoptosis by activation of the toll-like receptor 3 and interferon regulatory factor 3 pathways.

Dogusan Z, GarcĂ­a M, Flamez D, Alexopoulou L, Goldman M, Gysemans C, Mathieu C, Libert C, Eizirik DL, Rasschaert J.

Diabetes. 2008 May;57(5):1236-45. doi: 10.2337/db07-0844. Epub 2008 Jan 25.

5.

Activation of pattern recognition receptor-mediated innate immunity inhibits the replication of hepatitis B virus in human hepatocyte-derived cells.

Guo H, Jiang D, Ma D, Chang J, Dougherty AM, Cuconati A, Block TM, Guo JT.

J Virol. 2009 Jan;83(2):847-58. doi: 10.1128/JVI.02008-08. Epub 2008 Oct 29.

6.

Recognition of cytosolic DNA activates an IRF3-dependent innate immune response.

Stetson DB, Medzhitov R.

Immunity. 2006 Jan;24(1):93-103.

7.

Interferon regulatory factor IRF-7 induces the antiviral alpha interferon response and protects against lethal West Nile virus infection.

Daffis S, Samuel MA, Suthar MS, Keller BC, Gale M Jr, Diamond MS.

J Virol. 2008 Sep;82(17):8465-75. doi: 10.1128/JVI.00918-08. Epub 2008 Jun 18.

8.

Protein kinase Calpha is involved in interferon regulatory factor 3 activation and type I interferon-beta synthesis.

Johnson J, Albarani V, Nguyen M, Goldman M, Willems F, Aksoy E.

J Biol Chem. 2007 May 18;282(20):15022-32. Epub 2007 Feb 12.

9.

TRAF6 establishes innate immune responses by activating NF-kappaB and IRF7 upon sensing cytosolic viral RNA and DNA.

Konno H, Yamamoto T, Yamazaki K, Gohda J, Akiyama T, Semba K, Goto H, Kato A, Yujiri T, Imai T, Kawaguchi Y, Su B, Takeuchi O, Akira S, Tsunetsugu-Yokota Y, Inoue J.

PLoS One. 2009 May 25;4(5):e5674. doi: 10.1371/journal.pone.0005674.

10.

Pentraxin 3 protects from MCMV infection and reactivation through TLR sensing pathways leading to IRF3 activation.

Bozza S, Bistoni F, Gaziano R, Pitzurra L, Zelante T, Bonifazi P, Perruccio K, Bellocchio S, Neri M, Iorio AM, Salvatori G, De Santis R, Calvitti M, Doni A, Garlanda C, Mantovani A, Romani L.

Blood. 2006 Nov 15;108(10):3387-96. Epub 2006 Jul 13.

11.

Antiviral signaling through pattern recognition receptors.

Kawai T, Akira S.

J Biochem. 2007 Feb;141(2):137-45. Epub 2006 Dec 26. Review.

PMID:
17190786
12.

West Nile virus nonstructural protein 1 inhibits TLR3 signal transduction.

Wilson JR, de Sessions PF, Leon MA, Scholle F.

J Virol. 2008 Sep;82(17):8262-71. doi: 10.1128/JVI.00226-08. Epub 2008 Jun 18.

13.

TLR9-signaling pathways are involved in Kilham rat virus-induced autoimmune diabetes in the biobreeding diabetes-resistant rat.

Zipris D, Lien E, Nair A, Xie JX, Greiner DL, Mordes JP, Rossini AA.

J Immunol. 2007 Jan 15;178(2):693-701.

14.

Differential activation of IFN regulatory factor (IRF)-3 and IRF-5 transcription factors during viral infection.

Cheng TF, Brzostek S, Ando O, Van Scoy S, Kumar KP, Reich NC.

J Immunol. 2006 Jun 15;176(12):7462-70.

15.

Antiviral antibodies target adenovirus to phagolysosomes and amplify the innate immune response.

Zaiss AK, Vilaysane A, Cotter MJ, Clark SA, Meijndert HC, Colarusso P, Yates RM, Petrilli V, Tschopp J, Muruve DA.

J Immunol. 2009 Jun 1;182(11):7058-68. doi: 10.4049/jimmunol.0804269.

16.

Human immunodeficiency virus infection alters tumor necrosis factor alpha production via Toll-like receptor-dependent pathways in alveolar macrophages and U1 cells.

Nicol MQ, Mathys JM, Pereira A, Ollington K, Ieong MH, Skolnik PR.

J Virol. 2008 Aug;82(16):7790-8. doi: 10.1128/JVI.00362-08. Epub 2008 Jun 4.

17.

Adenovirus induction of IRF3 occurs through a binary trigger targeting Jun N-terminal kinase and TBK1 kinase cascades and type I interferon autocrine signaling.

Nociari M, Ocheretina O, Murphy M, Falck-Pedersen E.

J Virol. 2009 May;83(9):4081-91. doi: 10.1128/JVI.02591-08. Epub 2009 Feb 11.

18.

Acrolein with an alpha, beta-unsaturated carbonyl group inhibits LPS-induced homodimerization of toll-like receptor 4.

Lee JS, Lee JY, Lee MY, Hwang DH, Youn HS.

Mol Cells. 2008 Apr 30;25(2):253-7. Epub 2008 Mar 31.

19.

Cell-specific IRF-3 responses protect against West Nile virus infection by interferon-dependent and -independent mechanisms.

Daffis S, Samuel MA, Keller BC, Gale M Jr, Diamond MS.

PLoS Pathog. 2007 Jul 27;3(7):e106.

20.

Functional evolution of the TICAM-1 pathway for extrinsic RNA sensing.

Seya T, Matsumoto M, Ebihara T, Oshiumi H.

Immunol Rev. 2009 Jan;227(1):44-53. doi: 10.1111/j.1600-065X.2008.00723.x. Review.

PMID:
19120474

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