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Items: 1 to 20 of 74

1.

Feedback inhibition of calcineurin and Ras by a dual inhibitory protein Carabin.

Pan F, Sun L, Kardian DB, Whartenby KA, Pardoll DM, Liu JO.

Nature. 2007 Jan 25;445(7126):433-6. Epub 2007 Jan 17.

PMID:
17230191
2.

Carabin protects against cardiac hypertrophy by blocking calcineurin, Ras, and Ca2+/calmodulin-dependent protein kinase II signaling.

Bisserier M, Berthouze-Duquesnes M, Breckler M, Tortosa F, Fazal L, de Régibus A, Laurent AC, Varin A, Lucas A, Branchereau M, Marck P, Schickel JN, Deloménie C, Cazorla O, Soulas-Sprauel P, Crozatier B, Morel E, Heymes C, Lezoualc'h F.

Circulation. 2015 Jan 27;131(4):390-400; discussion 400. doi: 10.1161/CIRCULATIONAHA.114.010686. Epub 2014 Nov 4.

3.

A diacylglycerol-protein kinase C-RasGRP1 pathway directs Ras activation upon antigen receptor stimulation of T cells.

Roose JP, Mollenauer M, Gupta VA, Stone J, Weiss A.

Mol Cell Biol. 2005 Jun;25(11):4426-41.

4.
5.

Vav1 transduces T cell receptor signals to the activation of the Ras/ERK pathway via LAT, Sos, and RasGRP1.

Reynolds LF, de Bettignies C, Norton T, Beeser A, Chernoff J, Tybulewicz VL.

J Biol Chem. 2004 Apr 30;279(18):18239-46. Epub 2004 Feb 5.

6.

T cell receptor-induced calcineurin activation regulates T helper type 2 cell development by modifying the interleukin 4 receptor signaling complex.

Yamashita M, Katsumata M, Iwashima M, Kimura M, Shimizu C, Kamata T, Shin T, Seki N, Suzuki S, Taniguchi M, Nakayama T.

J Exp Med. 2000 Jun 5;191(11):1869-79.

8.

Hypophosphorylated TCR/CD3zeta signals through a Grb2-SOS1-Ras pathway in Lck knockdown cells.

Methi T, Ngai J, Vang T, Torgersen KM, Taskén K.

Eur J Immunol. 2007 Sep;37(9):2539-48.

9.
11.

The molecular functions of Shp2 in the Ras/Mitogen-activated protein kinase (ERK1/2) pathway.

Dance M, Montagner A, Salles JP, Yart A, Raynal P.

Cell Signal. 2008 Mar;20(3):453-9. Epub 2007 Oct 11. Review.

PMID:
17993263
12.

A functional T-cell receptor signaling pathway is required for p95vav activity.

Wu J, Katzav S, Weiss A.

Mol Cell Biol. 1995 Aug;15(8):4337-46.

13.

The Ca2+-dependent phosphatase calcineurin controls the formation of the Carma1-Bcl10-Malt1 complex during T cell receptor-induced NF-kappaB activation.

Palkowitsch L, Marienfeld U, Brunner C, Eitelhuber A, Krappmann D, Marienfeld RB.

J Biol Chem. 2011 Mar 4;286(9):7522-34. doi: 10.1074/jbc.M110.155895. Epub 2011 Jan 3.

14.

Vav modulation of the Ras/MEK/ERK signaling pathway plays a role in NFAT activation and CD69 up-regulation.

Villalba M, Hernandez J, Deckert M, Tanaka Y, Altman A.

Eur J Immunol. 2000 Jun;30(6):1587-96.

PMID:
10898494
15.

Phosphorylation of Tyr319 in ZAP-70 is required for T-cell antigen receptor-dependent phospholipase C-gamma1 and Ras activation.

Williams BL, Irvin BJ, Sutor SL, Chini CC, Yacyshyn E, Bubeck Wardenburg J, Dalton M, Chan AC, Abraham RT.

EMBO J. 1999 Apr 1;18(7):1832-44.

17.

Calcineurin inhibitors activate the proto-oncogene Ras and promote protumorigenic signals in renal cancer cells.

Datta D, Contreras AG, Basu A, Dormond O, Flynn E, Briscoe DM, Pal S.

Cancer Res. 2009 Dec 1;69(23):8902-9. doi: 10.1158/0008-5472.CAN-09-1404. Epub 2009 Nov 10.

18.

Expression of RALT, a feedback inhibitor of ErbB receptors, is subjected to an integrated transcriptional and post-translational control.

Fiorini M, Ballarò C, Sala G, Falcone G, Alemà S, Segatto O.

Oncogene. 2002 Sep 19;21(42):6530-9.

19.

Aberrant Ras regulation and reduced p190 tyrosine phosphorylation in cells lacking p120-Gap.

van der Geer P, Henkemeyer M, Jacks T, Pawson T.

Mol Cell Biol. 1997 Apr;17(4):1840-7.

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