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Items: 1 to 20 of 22

1.

Lymphocyte loss and immunosuppression following acetaminophen-induced hepatotoxicity in mice as a potential mechanism of tolerance.

Masson MJ, Peterson RA, Chung CJ, Graf ML, Carpenter LD, Ambroso JL, Krull DL, Sciarrotta J, Pohl LR.

Chem Res Toxicol. 2007 Jan;20(1):20-6.

PMID:
17226923
2.

Acetaminophen-induced immunosuppression associated with hepatotoxicity in mice.

Ueno K, Yamaura K, Nakamura T, Satoh T, Yano S.

Res Commun Mol Pathol Pharmacol. 2000;108(3-4):237-51.

PMID:
11913715
3.

Role of the coagulation system in acetaminophen-induced hepatotoxicity in mice.

Ganey PE, Luyendyk JP, Newport SW, Eagle TM, Maddox JF, Mackman N, Roth RA.

Hepatology. 2007 Oct;46(4):1177-86.

PMID:
17654741
4.

Mitochondrial protection by the JNK inhibitor leflunomide rescues mice from acetaminophen-induced liver injury.

Latchoumycandane C, Goh CW, Ong MM, Boelsterli UA.

Hepatology. 2007 Feb;45(2):412-21.

PMID:
17366662
5.

Two-dimensional database of mouse liver proteins: changes in hepatic protein levels following treatment with acetaminophen or its nontoxic regioisomer 3-acetamidophenol.

Fountoulakis M, Berndt P, Boelsterli UA, Crameri F, Winter M, Albertini S, Suter L.

Electrophoresis. 2000 Jun;21(11):2148-61.

PMID:
10892726
6.

Bacterial- and viral-induced inflammation increases sensitivity to acetaminophen hepatotoxicity.

Maddox JF, Amuzie CJ, Li M, Newport SW, Sparkenbaugh E, Cuff CF, Pestka JJ, Cantor GH, Roth RA, Ganey PE.

J Toxicol Environ Health A. 2010;73(1):58-73. doi: 10.1080/15287390903249057.

PMID:
19953420
7.

Pathologic role of stressed-induced glucocorticoids in drug-induced liver injury in mice.

Masson MJ, Collins LA, Carpenter LD, Graf ML, Ryan PM, Bourdi M, Pohl LR.

Biochem Biophys Res Commun. 2010 Jul 2;397(3):453-8. doi: 10.1016/j.bbrc.2010.05.126. Epub 2010 May 27.

8.

Acetaminophen hepatotoxicity in tumor necrosis factor/lymphotoxin-alpha gene knockout mice.

Boess F, Bopst M, Althaus R, Polsky S, Cohen SD, Eugster HP, Boelsterli UA.

Hepatology. 1998 Apr;27(4):1021-9.

PMID:
9537442
9.

Fas receptor-deficient lpr mice are protected against acetaminophen hepatotoxicity due to higher glutathione synthesis and enhanced detoxification of oxidant stress.

Williams CD, McGill MR, Farhood A, Jaeschke H.

Food Chem Toxicol. 2013 Aug;58:228-35. doi: 10.1016/j.fct.2013.04.031. Epub 2013 Apr 27.

10.

Innate immune system plays a critical role in determining the progression and severity of acetaminophen hepatotoxicity.

Liu ZX, Govindarajan S, Kaplowitz N.

Gastroenterology. 2004 Dec;127(6):1760-74.

PMID:
15578514
11.

Arjunolic acid, a triterpenoid saponin, prevents acetaminophen (APAP)-induced liver and hepatocyte injury via the inhibition of APAP bioactivation and JNK-mediated mitochondrial protection.

Ghosh J, Das J, Manna P, Sil PC.

Free Radic Biol Med. 2010 Feb 15;48(4):535-53. doi: 10.1016/j.freeradbiomed.2009.11.023. Epub 2009 Dec 4.

PMID:
19969075
12.

Protective effect of diallyl sulfone against acetaminophen-induced hepatotoxicity in mice.

Lin MC, Wang EJ, Patten C, Lee MJ, Xiao F, Reuhl KR, Yang CS.

J Biochem Toxicol. 1996;11(1):11-20.

PMID:
8806047
13.

Contribution of acetaminophen-cysteine to acetaminophen nephrotoxicity in CD-1 mice: I. Enhancement of acetaminophen nephrotoxicity by acetaminophen-cysteine.

Stern ST, Bruno MK, Hennig GE, Horton RA, Roberts JC, Cohen SD.

Toxicol Appl Pharmacol. 2005 Jan 15;202(2):151-9.

PMID:
15629190
14.

Protective effects of garlic and related organosulfur compounds on acetaminophen-induced hepatotoxicity in mice.

Wang EJ, Li Y, Lin M, Chen L, Stein AP, Reuhl KR, Yang CS.

Toxicol Appl Pharmacol. 1996 Jan;136(1):146-54.

PMID:
8560468
15.

Protection against acetaminophen toxicity in CYP1A2 and CYP2E1 double-null mice.

Zaher H, Buters JT, Ward JM, Bruno MK, Lucas AM, Stern ST, Cohen SD, Gonzalez FJ.

Toxicol Appl Pharmacol. 1998 Sep;152(1):193-9.

PMID:
9772215
16.

Acute acetaminophen intoxication leads to hepatic iron loading by decreased hepcidin synthesis.

van Swelm RP, Laarakkers CM, Blous L, Peters JG, Blaney Davidson EN, van der Kraan PM, Swinkels DW, Masereeuw R, Russel FG.

Toxicol Sci. 2012 Sep;129(1):225-33. doi: 10.1093/toxsci/kfs176. Epub 2012 May 18.

PMID:
22610607
18.

Tolerogenic role of Kupffer cells in allergic reactions.

Ju C, McCoy JP, Chung CJ, Graf ML, Pohl LR.

Chem Res Toxicol. 2003 Dec;16(12):1514-9.

PMID:
14680364
19.

Protection against acetaminophen hepatotoxicity by a single dose of clofibrate: effects on selective protein arylation and glutathione depletion.

Manautou JE, Emeigh Hart SG, Khairallah EA, Cohen SD.

Fundam Appl Toxicol. 1996 Feb;29(2):229-37.

PMID:
8742320
20.

S-Adenosylmethionine (SAMe) attenuates acetaminophen hepatotoxicity in C57BL/6 mice.

Valentovic M, Terneus M, Harmon RC, Carpenter AB.

Toxicol Lett. 2004 Dec 30;154(3):165-74.

PMID:
15501608

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