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Detection of human CYP2C8, CYP2C9, and CYP2J2 in cardiovascular tissues.

Delozier TC, Kissling GE, Coulter SJ, Dai D, Foley JF, Bradbury JA, Murphy E, Steenbergen C, Zeldin DC, Goldstein JA.

Drug Metab Dispos. 2007 Apr;35(4):682-8. Epub 2007 Jan 12.


Association of CYP2C8, CYP2C9 and CYP2J2 gene polymorphisms with myocardial infarction in South Indian population.

Arun Kumar AS, Kumar SS, Umamaheswaran G, Kesavan R, Balachandar J, Adithan C.

Pharmacol Rep. 2015 Feb;67(1):97-101. doi: 10.1016/j.pharep.2014.08.010. Epub 2014 Sep 11.


CYP2J2 and CYP2C8 polymorphisms and coronary heart disease risk: the Atherosclerosis Risk in Communities (ARIC) study.

Lee CR, North KE, Bray MS, Couper DJ, Heiss G, Zeldin DC.

Pharmacogenet Genomics. 2007 May;17(5):349-58.


Endothelial expression of human cytochrome P450 epoxygenase CYP2C8 increases susceptibility to ischemia-reperfusion injury in isolated mouse heart.

Edin ML, Wang Z, Bradbury JA, Graves JP, Lih FB, DeGraff LM, Foley JF, Torphy R, Ronnekleiv OK, Tomer KB, Lee CR, Zeldin DC.

FASEB J. 2011 Oct;25(10):3436-47. doi: 10.1096/fj.11-188300. Epub 2011 Jun 22.


Single nucleotide polymorphisms in the CYP2J2 and CYP2C8 genes and the risk of hypertension.

King LM, Gainer JV, David GL, Dai D, Goldstein JA, Brown NJ, Zeldin DC.

Pharmacogenet Genomics. 2005 Jan;15(1):7-13.


Differential expression and function of CYP2C isoforms in human intestine and liver.

Läpple F, von Richter O, Fromm MF, Richter T, Thon KP, Wisser H, Griese EU, Eichelbaum M, Kivistö KT.

Pharmacogenetics. 2003 Sep;13(9):565-75.


Role of cytochrome P450 2C8 and 2J2 genotypes in calcineurin inhibitor-induced chronic kidney disease.

Smith HE, Jones JP 3rd, Kalhorn TF, Farin FM, Stapleton PL, Davis CL, Perkins JD, Blough DK, Hebert MF, Thummel KE, Totah RA.

Pharmacogenet Genomics. 2008 Nov;18(11):943-53. doi: 10.1097/FPC.0b013e32830e1e16.


Molecular cloning, expression, and functional significance of a cytochrome P450 highly expressed in rat heart myocytes.

Wu S, Chen W, Murphy E, Gabel S, Tomer KB, Foley J, Steenbergen C, Falck JR, Moomaw CR, Zeldin DC.

J Biol Chem. 1997 May 9;272(19):12551-9.


Sex- and isoform-specific mechanism of neuroprotection by transgenic expression of P450 epoxygenase in vascular endothelium.

Jia J, Davis CM, Zhang W, Edin ML, Jouihan S, Jia T, Bradbury JA, Graves JP, DeGraff LM, Lee CR, Ronnekleiv O, Wang R, Xu Y, Zeldin DC, Alkayed NJ.

Exp Neurol. 2016 May;279:75-85. doi: 10.1016/j.expneurol.2016.02.016. Epub 2016 Feb 20.


Common variation in cytochrome P450 epoxygenase genes and the risk of incident nonfatal myocardial infarction and ischemic stroke.

Marciante KD, Totah RA, Heckbert SR, Smith NL, Lemaitre RN, Lumley T, Rice KM, Hindorff LA, Bis JC, Hartman B, Psaty BM.

Pharmacogenet Genomics. 2008 Jun;18(6):535-43. doi: 10.1097/FPC.0b013e3282fd1287.


Genetic markers in the EET metabolic pathway are associated with outcomes in patients with aneurysmal subarachnoid hemorrhage.

Donnelly MK, Conley YP, Crago EA, Ren D, Sherwood PR, Balzer JR, Poloyac SM.

J Cereb Blood Flow Metab. 2015 Feb;35(2):267-76. doi: 10.1038/jcbfm.2014.195. Epub 2014 Nov 12.


Molecular cloning and expression of CYP2J2, a human cytochrome P450 arachidonic acid epoxygenase highly expressed in heart.

Wu S, Moomaw CR, Tomer KB, Falck JR, Zeldin DC.

J Biol Chem. 1996 Feb 16;271(7):3460-8.


Expression of cytochrome P450 arachidonic acid epoxygenase 2J2 in human tumor tissues and cell lines.

Jiang JG, Fu XN, Chen CL, Wang DW.

Ai Zheng. 2009 Feb;28(2):93-6. Epub 2009 Feb 23.


Hepatocyte nuclear factor 4{alpha} regulates rifampicin-mediated induction of CYP2C genes in primary cultures of human hepatocytes.

Rana R, Chen Y, Ferguson SS, Kissling GE, Surapureddi S, Goldstein JA.

Drug Metab Dispos. 2010 Apr;38(4):591-9. doi: 10.1124/dmd.109.030387. Epub 2010 Jan 19.


Identification of the fetal liver cytochrome CYP3A7 in human endometrium and placenta.

Schuetz JD, Kauma S, Guzelian PS.

J Clin Invest. 1993 Aug;92(2):1018-24.


Variability of CYP2J2 expression in human fetal tissues.

Gaedigk A, Baker DW, Totah RA, Gaedigk R, Pearce RE, Vyhlidal CA, Zeldin DC, Leeder JS.

J Pharmacol Exp Ther. 2006 Nov;319(2):523-32. Epub 2006 Jul 25.


[Expression of cytochrome P450 enzymes in human nasopharyngeal carcinoma and non-cancerous nasopharynx tissue].

Jiang JH, Jia WH, Qin HD, Liang H, Pan ZG, Zeng YX.

Ai Zheng. 2004 Jun;23(6):672-7. Chinese.


Genetic variation in the cytochrome P450 epoxygenase pathway and cardiovascular disease risk.

Theken KN, Lee CR.

Pharmacogenomics. 2007 Oct;8(10):1369-83. Review.


The Prevalence of CYP2C8, 2C9, 2J2, and soluble epoxide hydrolase polymorphisms in African Americans with hypertension.

Dreisbach AW, Japa S, Sigel A, Parenti MB, Hess AE, Srinouanprachanh SL, Rettie AE, Kim H, Farin FM, Hamm LL, Lertora JJ.

Am J Hypertens. 2005 Oct;18(10):1276-81.


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