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Items: 1 to 20 of 167

1.

aPKC-mediated phosphorylation regulates asymmetric membrane localization of the cell fate determinant Numb.

Smith CA, Lau KM, Rahmani Z, Dho SE, Brothers G, She YM, Berry DM, Bonneil E, Thibault P, Schweisguth F, Le Borgne R, McGlade CJ.

EMBO J. 2007 Jan 24;26(2):468-80. Epub 2007 Jan 4.

2.

Asymmetric localization of Numb:EGFP in dividing neuroepithelial cells during neurulation in Danio rerio.

Reugels AM, Boggetti B, Scheer N, Campos-Ortega JA.

Dev Dyn. 2006 Apr;235(4):934-48.

3.

Quantitative analysis of protein dynamics during asymmetric cell division.

Mayer B, Emery G, Berdnik D, Wirtz-Peitz F, Knoblich JA.

Curr Biol. 2005 Oct 25;15(20):1847-54.

4.

Cortical aPKC kinase activity distinguishes neural stem cells from progenitor cells by ensuring asymmetric segregation of Numb.

Haenfler JM, Kuang C, Lee CY.

Dev Biol. 2012 May 1;365(1):219-28. doi: 10.1016/j.ydbio.2012.02.027. Epub 2012 Feb 25.

5.

A novel transmembrane protein recruits numb to the plasma membrane during asymmetric cell division.

Qin H, Percival-Smith A, Li C, Jia CY, Gloor G, Li SS.

J Biol Chem. 2004 Mar 19;279(12):11304-12. Epub 2003 Dec 11.

6.

The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl.

Betschinger J, Mechtler K, Knoblich JA.

Nature. 2003 Mar 20;422(6929):326-30. Epub 2003 Mar 9.

PMID:
12629552
7.

Asymmetric localization of a mammalian numb homolog during mouse cortical neurogenesis.

Zhong W, Feder JN, Jiang MM, Jan LY, Jan YN.

Neuron. 1996 Jul;17(1):43-53.

8.

Protein phosphatase 2A negatively regulates aPKC signaling by modulating phosphorylation of Par-6 in Drosophila neuroblast asymmetric divisions.

Ogawa H, Ohta N, Moon W, Matsuzaki F.

J Cell Sci. 2009 Sep 15;122(Pt 18):3242-9. doi: 10.1242/jcs.050955. Epub 2009 Aug 18.

9.

Overexpression of partner of numb induces asymmetric distribution of the PI4P 5-Kinase Skittles in mitotic sensory organ precursor cells in Drosophila.

Perdigoto CN, Gervais L, Overstreet E, Fischer J, Guichet A, Schweisguth F.

PLoS One. 2008 Aug 27;3(8):e3072. doi: 10.1371/journal.pone.0003072.

10.

Numb regulates cell-cell adhesion and polarity in response to tyrosine kinase signalling.

Wang Z, Sandiford S, Wu C, Li SS.

EMBO J. 2009 Aug 19;28(16):2360-73. doi: 10.1038/emboj.2009.190. Epub 2009 Jul 16.

11.

Linking cell cycle to asymmetric division: Aurora-A phosphorylates the Par complex to regulate Numb localization.

Wirtz-Peitz F, Nishimura T, Knoblich JA.

Cell. 2008 Oct 3;135(1):161-73. doi: 10.1016/j.cell.2008.07.049.

12.

KIBRA suppresses apical exocytosis through inhibition of aPKC kinase activity in epithelial cells.

Yoshihama Y, Sasaki K, Horikoshi Y, Suzuki A, Ohtsuka T, Hakuno F, Takahashi S, Ohno S, Chida K.

Curr Biol. 2011 Apr 26;21(8):705-11. doi: 10.1016/j.cub.2011.03.029. Epub 2011 Apr 14.

13.

aPKC phosphorylates Miranda to polarize fate determinants during neuroblast asymmetric cell division.

Atwood SX, Prehoda KE.

Curr Biol. 2009 May 12;19(9):723-9. doi: 10.1016/j.cub.2009.03.056. Epub 2009 Apr 16.

14.

Involvement of ASIP/PAR-3 in the promotion of epithelial tight junction formation.

Hirose T, Izumi Y, Nagashima Y, Tamai-Nagai Y, Kurihara H, Sakai T, Suzuki Y, Yamanaka T, Suzuki A, Mizuno K, Ohno S.

J Cell Sci. 2002 Jun 15;115(Pt 12):2485-95.

15.

A polarity complex of mPar-6 and atypical PKC binds, phosphorylates and regulates mammalian Lgl.

Plant PJ, Fawcett JP, Lin DC, Holdorf AD, Binns K, Kulkarni S, Pawson T.

Nat Cell Biol. 2003 Apr;5(4):301-8.

PMID:
12629547
16.

Phosphorylation of Numb regulates its interaction with the clathrin-associated adaptor AP-2.

Tokumitsu H, Hatano N, Yokokura S, Sueyoshi Y, Nozaki N, Kobayashi R.

FEBS Lett. 2006 Oct 16;580(24):5797-801. Epub 2006 Sep 27.

17.

Localization-dependent and -independent roles of numb contribute to cell-fate specification in Drosophila.

Bhalerao S, Berdnik D, Török T, Knoblich JA.

Curr Biol. 2005 Sep 6;15(17):1583-90.

18.

Numb inhibits the recycling of Sanpodo in Drosophila sensory organ precursor.

Cotton M, Benhra N, Le Borgne R.

Curr Biol. 2013 Apr 8;23(7):581-7. doi: 10.1016/j.cub.2013.02.020. Epub 2013 Mar 21.

19.
20.

Planar Cell Polarity Breaks the Symmetry of PAR Protein Distribution prior to Mitosis in Drosophila Sensory Organ Precursor Cells.

Besson C, Bernard F, Corson F, Rouault H, Reynaud E, Keder A, Mazouni K, Schweisguth F.

Curr Biol. 2015 Apr 20;25(8):1104-10. doi: 10.1016/j.cub.2015.02.073. Epub 2015 Apr 2.

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