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Items: 1 to 20 of 62

1.

A novel human primary immunodeficiency syndrome caused by deficiency of the endosomal adaptor protein p14.

Bohn G, Allroth A, Brandes G, Thiel J, Glocker E, Schäffer AA, Rathinam C, Taub N, Teis D, Zeidler C, Dewey RA, Geffers R, Buer J, Huber LA, Welte K, Grimbacher B, Klein C.

Nat Med. 2007 Jan;13(1):38-45.

PMID:
17195838
2.

Bad signals jam organelle traffic.

Dell'Angelica EC.

Nat Med. 2007 Jan;13(1):31-2. No abstract available.

PMID:
17206132
3.

A novel 14-kilodalton protein interacts with the mitogen-activated protein kinase scaffold mp1 on a late endosomal/lysosomal compartment.

Wunderlich W, Fialka I, Teis D, Alpi A, Pfeifer A, Parton RG, Lottspeich F, Huber LA.

J Cell Biol. 2001 Feb 19;152(4):765-76.

4.

The late endosomal adaptor molecule p14 (LAMTOR2) represents a novel regulator of Langerhans cell homeostasis.

Sparber F, Scheffler JM, Amberg N, Tripp CH, Heib V, Hermann M, Zahner SP, Clausen BE, Reizis B, Huber LA, Stoitzner P, Romani N.

Blood. 2014 Jan 9;123(2):217-27. doi: 10.1182/blood-2013-08-518555.

5.

A clathrin-dependent pathway leads to KRas signaling on late endosomes en route to lysosomes.

Lu A, Tebar F, Alvarez-Moya B, López-Alcalá C, Calvo M, Enrich C, Agell N, Nakamura T, Matsuda M, Bachs O.

J Cell Biol. 2009 Mar 23;184(6):863-79. doi: 10.1083/jcb.200807186.

6.

Hypomorphic mutation of ZAP70 in human results in a late onset immunodeficiency and no autoimmunity.

Picard C, Dogniaux S, Chemin K, Maciorowski Z, Lim A, Mazerolles F, Rieux-Laucat F, Stolzenberg MC, Debre M, Magny JP, Le Deist F, Fischer A, Hivroz C.

Eur J Immunol. 2009 Jul;39(7):1966-76. doi: 10.1002/eji.200939385.

7.

Crystal structure of the p14/MP1 scaffolding complex: how a twin couple attaches mitogen-activated protein kinase signaling to late endosomes.

Kurzbauer R, Teis D, de Araujo ME, Maurer-Stroh S, Eisenhaber F, Bourenkov GP, Bartunik HD, Hekman M, Rapp UR, Huber LA, Clausen T.

Proc Natl Acad Sci U S A. 2004 Jul 27;101(30):10984-9.

8.

The novel lipid raft adaptor p18 controls endosome dynamics by anchoring the MEK-ERK pathway to late endosomes.

Nada S, Hondo A, Kasai A, Koike M, Saito K, Uchiyama Y, Okada M.

EMBO J. 2009 Mar 4;28(5):477-89. doi: 10.1038/emboj.2008.308.

9.

Structure of the adaptor protein p14 reveals a profilin-like fold with distinct function.

Qian C, Zhang Q, Wang X, Zeng L, Farooq A, Zhou MM.

J Mol Biol. 2005 Mar 25;347(2):309-21.

PMID:
15740743
10.

A complex immunodeficiency is based on U1 snRNP-mediated poly(A) site suppression.

Langemeier J, Schrom EM, Rabner A, Radtke M, Zychlinski D, Saborowski A, Bohn G, Mandel-Gutfreund Y, Bodem J, Klein C, Bohne J.

EMBO J. 2012 Oct 17;31(20):4035-44. doi: 10.1038/emboj.2012.252.

11.

Aggregation of endosomal-vacuolar compartments in the Aovps24-deleted strain in the filamentous fungus Aspergillus oryzae.

Tatsumi A, Shoji JY, Kikuma T, Arioka M, Kitamoto K.

Biochem Biophys Res Commun. 2007 Oct 19;362(2):474-9.

PMID:
17719006
12.

Functions of adaptor protein (AP)-3 and AP-1 in tyrosinase sorting from endosomes to melanosomes.

Theos AC, Tenza D, Martina JA, Hurbain I, Peden AA, Sviderskaya EV, Stewart A, Robinson MS, Bennett DC, Cutler DF, Bonifacino JS, Marks MS, Raposo G.

Mol Biol Cell. 2005 Nov;16(11):5356-72.

13.

CHMP7, a novel ESCRT-III-related protein, associates with CHMP4b and functions in the endosomal sorting pathway.

Horii M, Shibata H, Kobayashi R, Katoh K, Yorikawa C, Yasuda J, Maki M.

Biochem J. 2006 Nov 15;400(1):23-32.

14.

A role for the lysosomal membrane protein LGP85 in the biogenesis and maintenance of endosomal and lysosomal morphology.

Kuronita T, Eskelinen EL, Fujita H, Saftig P, Himeno M, Tanaka Y.

J Cell Sci. 2002 Nov 1;115(Pt 21):4117-31.

15.

p14-MP1-MEK1 signaling regulates endosomal traffic and cellular proliferation during tissue homeostasis.

Teis D, Taub N, Kurzbauer R, Hilber D, de Araujo ME, Erlacher M, Offterdinger M, Villunger A, Geley S, Bohn G, Klein C, Hess MW, Huber LA.

J Cell Biol. 2006 Dec 18;175(6):861-8.

16.

Lysosome-related organelles: a view from immunity and pigmentation.

Raposo G, Fevrier B, Stoorvogel W, Marks MS.

Cell Struct Funct. 2002 Dec;27(6):443-56. Review.

17.

Adaptor protein complexes AP-4 and AP-5: new players in endosomal trafficking and progressive spastic paraplegia.

Hirst J, Irving C, Borner GH.

Traffic. 2013 Feb;14(2):153-64. doi: 10.1111/tra.12028. Review.

18.

Interactions between kinase scaffold MP1/p14 and its endosomal anchoring protein p18.

Magee J, Cygler M.

Biochemistry. 2011 May 10;50(18):3696-705. doi: 10.1021/bi101972y.

PMID:
21452851
19.

The structure of the MAPK scaffold, MP1, bound to its partner, p14. A complex with a critical role in endosomal map kinase signaling.

Lunin VV, Munger C, Wagner J, Ye Z, Cygler M, Sacher M.

J Biol Chem. 2004 May 28;279(22):23422-30.

20.

Distribution and dynamics of Lamp1-containing endocytic organelles in fibroblasts deficient in BLOC-3.

Falcón-Pérez JM, Nazarian R, Sabatti C, Dell'Angelica EC.

J Cell Sci. 2005 Nov 15;118(Pt 22):5243-55.

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