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Items: 1 to 20 of 114

1.

Rosiglitazone attenuates hypoxia-induced pulmonary arterial remodeling.

Crossno JT Jr, Garat CV, Reusch JE, Morris KG, Dempsey EC, McMurtry IF, Stenmark KR, Klemm DJ.

Am J Physiol Lung Cell Mol Physiol. 2007 Apr;292(4):L885-97. Epub 2006 Dec 22.

2.

Inhibition of phosphatidylinositol 3-kinase/Akt signaling attenuates hypoxia-induced pulmonary artery remodeling and suppresses CREB depletion in arterial smooth muscle cells.

Garat CV, Crossno JT Jr, Sullivan TM, Reusch JE, Klemm DJ.

J Cardiovasc Pharmacol. 2013 Dec;62(6):539-48. doi: 10.1097/FJC.0000000000000014.

3.

Lysyl oxidases play a causal role in vascular remodeling in clinical and experimental pulmonary arterial hypertension.

Nave AH, Mižíková I, Niess G, Steenbock H, Reichenberger F, Talavera ML, Veit F, Herold S, Mayer K, Vadász I, Weissmann N, Seeger W, Brinckmann J, Morty RE.

Arterioscler Thromb Vasc Biol. 2014 Jul;34(7):1446-58. doi: 10.1161/ATVBAHA.114.303534. Epub 2014 May 15.

4.

Thiazolidinediones prevent PDGF-BB-induced CREB depletion in pulmonary artery smooth muscle cells by preventing upregulation of casein kinase 2 alpha' catalytic subunit.

Garat CV, Crossno JT Jr, Sullivan TM, Reusch JE, Klemm DJ.

J Cardiovasc Pharmacol. 2010 May;55(5):469-80. doi: 10.1097/FJC.0b013e3181d64dbe.

5.

Reduction of reactive oxygen species prevents hypoxia-induced CREB depletion in pulmonary artery smooth muscle cells.

Klemm DJ, Majka SM, Crossno JT Jr, Psilas JC, Reusch JE, Garat CV.

J Cardiovasc Pharmacol. 2011 Aug;58(2):181-91. doi: 10.1097/FJC.0b013e31821f2773.

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8.

NADPH oxidase 4 is expressed in pulmonary artery adventitia and contributes to hypertensive vascular remodeling.

Barman SA, Chen F, Su Y, Dimitropoulou C, Wang Y, Catravas JD, Han W, Orfi L, Szantai-Kis C, Keri G, Szabadkai I, Barabutis N, Rafikova O, Rafikov R, Black SM, Jonigk D, Giannis A, Asmis R, Stepp DW, Ramesh G, Fulton DJ.

Arterioscler Thromb Vasc Biol. 2014 Aug;34(8):1704-15. doi: 10.1161/ATVBAHA.114.303848. Epub 2014 Jun 19.

9.

Long-term inhibition of Rho kinase with fasudil attenuates high flow induced pulmonary artery remodeling in rats.

Li F, Xia W, Li A, Zhao C, Sun R.

Pharmacol Res. 2007 Jan;55(1):64-71. Epub 2006 Nov 1.

PMID:
17127075
10.

Inhibition of rho kinase attenuates high flow induced pulmonary hypertension in rats.

Li FH, Xia W, Li AW, Zhao CF, Sun RP.

Chin Med J (Engl). 2007 Jan 5;120(1):22-9.

PMID:
17254483
11.

The Nox4 inhibitor GKT137831 attenuates hypoxia-induced pulmonary vascular cell proliferation.

Green DE, Murphy TC, Kang BY, Kleinhenz JM, Szyndralewiez C, Page P, Sutliff RL, Hart CM.

Am J Respir Cell Mol Biol. 2012 Nov;47(5):718-26. doi: 10.1165/rcmb.2011-0418OC. Epub 2012 Aug 16.

12.

Therapeutic efficacy of valproic acid in a combined monocrotaline and chronic hypoxia rat model of severe pulmonary hypertension.

Lan B, Hayama E, Kawaguchi N, Furutani Y, Nakanishi T.

PLoS One. 2015 Jan 28;10(1):e0117211. doi: 10.1371/journal.pone.0117211. eCollection 2015.

13.

Metalloproteinase inhibition by Batimastat attenuates pulmonary hypertension in chronically hypoxic rats.

Herget J, Novotna J, Bibova J, Povysilova V, Vankova M, Hampl V.

Am J Physiol Lung Cell Mol Physiol. 2003 Jul;285(1):L199-208. Epub 2003 Mar 28.

14.

Dominant negative mutation of the TGF-beta receptor blocks hypoxia-induced pulmonary vascular remodeling.

Chen YF, Feng JA, Li P, Xing D, Zhang Y, Serra R, Ambalavanan N, Majid-Hassan E, Oparil S.

J Appl Physiol (1985). 2006 Feb;100(2):564-71. Epub 2005 Oct 13.

15.

Inhibition of matrix metalloproteinases by lung TIMP-1 gene transfer or doxycycline aggravates pulmonary hypertension in rats.

Vieillard-Baron A, Frisdal E, Eddahibi S, Deprez I, Baker AH, Newby AC, Berger P, Levame M, Raffestin B, Adnot S, d'Ortho MP.

Circ Res. 2000 Sep 1;87(5):418-25.

16.

Involvement of RhoA/Rho kinase signaling in pulmonary hypertension of the fawn-hooded rat.

Nagaoka T, Gebb SA, Karoor V, Homma N, Morris KG, McMurtry IF, Oka M.

J Appl Physiol (1985). 2006 Mar;100(3):996-1002. Epub 2005 Dec 1.

17.

Rosiglitazone attenuates hypoxia-induced pulmonary arterial hypertension in rats.

Kim EK, Lee JH, Oh YM, Lee YS, Lee SD.

Respirology. 2010 May;15(4):659-68. doi: 10.1111/j.1440-1843.2010.01756.x.

PMID:
20546541
18.

The role of collagen in extralobar pulmonary artery stiffening in response to hypoxia-induced pulmonary hypertension.

Ooi CY, Wang Z, Tabima DM, Eickhoff JC, Chesler NC.

Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H1823-31. doi: 10.1152/ajpheart.00493.2009. Epub 2010 Sep 17.

19.

Inhibition of matrix metalloproteinases by lung TIMP-1 gene transfer limits monocrotaline-induced pulmonary vascular remodeling in rats.

Vieillard-Baron A, Frisdal E, Raffestin B, Baker AH, Eddahibi S, Adnot S, D'Ortho MP.

Hum Gene Ther. 2003 Jun 10;14(9):861-9.

PMID:
12828857
20.

[Expression and activity of RhoA/Rho kinase in remodeling of high blood flow pulmonary vessels.].

Li FH, Xia W, Sun RP.

Zhonghua Er Ke Za Zhi. 2007 May;45(5):387-92. Chinese.

PMID:
17697629

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