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Items: 1 to 20 of 112

1.

Function and biological roles of the Dickkopf family of Wnt modulators.

Niehrs C.

Oncogene. 2006 Dec 4;25(57):7469-81. Review.

PMID:
17143291
2.

LDL-receptor-related protein 6 is a receptor for Dickkopf proteins.

Mao B, Wu W, Li Y, Hoppe D, Stannek P, Glinka A, Niehrs C.

Nature. 2001 May 17;411(6835):321-5.

PMID:
11357136
3.

SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor.

Semënov M, Tamai K, He X.

J Biol Chem. 2005 Jul 22;280(29):26770-5.

4.

Frequent epigenetic inactivation of DICKKOPF family genes in human gastrointestinal tumors.

Sato H, Suzuki H, Toyota M, Nojima M, Maruyama R, Sasaki S, Takagi H, Sogabe Y, Sasaki Y, Idogawa M, Sonoda T, Mori M, Imai K, Tokino T, Shinomura Y.

Carcinogenesis. 2007 Dec;28(12):2459-66.

PMID:
17675336
5.

Functional and structural diversity of the human Dickkopf gene family.

Krupnik VE, Sharp JD, Jiang C, Robison K, Chickering TW, Amaravadi L, Brown DE, Guyot D, Mays G, Leiby K, Chang B, Duong T, Goodearl AD, Gearing DP, Sokol SY, McCarthy SA.

Gene. 1999 Oct 1;238(2):301-13.

PMID:
10570958
6.

Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6.

Semënov MV, Tamai K, Brott BK, Kühl M, Sokol S, He X.

Curr Biol. 2001 Jun 26;11(12):951-61.

7.

Kremen2 modulates Dickkopf2 activity during Wnt/LRP6 signaling.

Mao B, Niehrs C.

Gene. 2003 Jan 2;302(1-2):179-83.

PMID:
12527209
8.

Mutual antagonism between dickkopf1 and dickkopf2 regulates Wnt/beta-catenin signalling.

Wu W, Glinka A, Delius H, Niehrs C.

Curr Biol. 2000 Dec 14-28;10(24):1611-4.

9.

Dkk1-induced inhibition of Wnt signaling in osteoblast differentiation is an underlying mechanism of bone loss in multiple myeloma.

Qiang YW, Barlogie B, Rudikoff S, Shaughnessy JD Jr.

Bone. 2008 Apr;42(4):669-80. doi: 10.1016/j.bone.2007.12.006.

PMID:
18294945
10.

Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling.

Mao B, Wu W, Davidson G, Marhold J, Li M, Mechler BM, Delius H, Hoppe D, Stannek P, Walter C, Glinka A, Niehrs C.

Nature. 2002 Jun 6;417(6889):664-7.

PMID:
12050670
11.

Kremen proteins interact with Dickkopf1 to regulate anteroposterior CNS patterning.

Davidson G, Mao B, del Barco Barrantes I, Niehrs C.

Development. 2002 Dec;129(24):5587-96. Erratum in: Development. 2003 Jan;130(2):425..

12.

Low-density lipoprotein receptor-related protein 5 (LRP5) mediates the prostate cancer-induced formation of new bone.

Li ZG, Yang J, Vazquez ES, Rose D, Vakar-Lopez F, Mathew P, Lopez A, Logothetis CJ, Lin SH, Navone NM.

Oncogene. 2008 Jan 24;27(5):596-603.

PMID:
17700537
13.

Wnt signaling and osteoblastogenesis.

Bodine PV, Komm BS.

Rev Endocr Metab Disord. 2006 Jun;7(1-2):33-9. Review.

PMID:
16960757
14.

Structure-based mutation analysis shows the importance of LRP5 beta-propeller 1 in modulating Dkk1-mediated inhibition of Wnt signaling.

Bhat BM, Allen KM, Liu W, Graham J, Morales A, Anisowicz A, Lam HS, McCauley C, Coleburn V, Cain M, Fortier E, Bhat RA, Bex FJ, Yaworsky PJ.

Gene. 2007 Apr 15;391(1-2):103-12.

PMID:
17276019
15.

Requirement of prorenin receptor and vacuolar H+-ATPase-mediated acidification for Wnt signaling.

Cruciat CM, Ohkawara B, Acebron SP, Karaulanov E, Reinhard C, Ingelfinger D, Boutros M, Niehrs C.

Science. 2010 Jan 22;327(5964):459-63. doi: 10.1126/science.1179802.

16.

[Wnt signaling and bone metabolism].

Asaba H, Sakai J.

Clin Calcium. 2005 May;15(5):813-8. Japanese.

PMID:
15876744
17.

Dynamic expression of Wnt signaling-related Dickkopf1, -2, and -3 mRNAs in the developing mouse tooth.

Fjeld K, Kettunen P, Furmanek T, Kvinnsland IH, Luukko K.

Dev Dyn. 2005 May;233(1):161-6.

18.

LRP5 mutations in osteoporosis-pseudoglioma syndrome and high-bone-mass disorders.

Levasseur R, Lacombe D, de Vernejoul MC.

Joint Bone Spine. 2005 May;72(3):207-14. Review.

PMID:
15850991
19.

An ancient Wnt-Dickkopf antagonism in Hydra.

Guder C, Pinho S, Nacak TG, Schmidt HA, Hobmayer B, Niehrs C, Holstein TW.

Development. 2006 Mar;133(5):901-11.

20.

Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia.

Li J, Sarosi I, Cattley RC, Pretorius J, Asuncion F, Grisanti M, Morony S, Adamu S, Geng Z, Qiu W, Kostenuik P, Lacey DL, Simonet WS, Bolon B, Qian X, Shalhoub V, Ominsky MS, Zhu Ke H, Li X, Richards WG.

Bone. 2006 Oct;39(4):754-66.

PMID:
16730481

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