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Items: 1 to 20 of 95

1.

Hyperphagia, severe obesity, impaired cognitive function, and hyperactivity associated with functional loss of one copy of the brain-derived neurotrophic factor (BDNF) gene.

Gray J, Yeo GS, Cox JJ, Morton J, Adlam AL, Keogh JM, Yanovski JA, El Gharbawy A, Han JC, Tung YC, Hodges JR, Raymond FL, O'rahilly S, Farooqi IS.

Diabetes. 2006 Dec;55(12):3366-71.

2.

Brain-derived neurotrophic factor and obesity in the WAGR syndrome.

Han JC, Liu QR, Jones M, Levinn RL, Menzie CM, Jefferson-George KS, Adler-Wailes DC, Sanford EL, Lacbawan FL, Uhl GR, Rennert OM, Yanovski JA.

N Engl J Med. 2008 Aug 28;359(9):918-27. doi: 10.1056/NEJMoa0801119. Erratum in: N Engl J Med. 2008 Sep 25;359(13):1414.

3.

Rai1 haploinsufficiency causes reduced Bdnf expression resulting in hyperphagia, obesity and altered fat distribution in mice and humans with no evidence of metabolic syndrome.

Burns B, Schmidt K, Williams SR, Kim S, Girirajan S, Elsea SH.

Hum Mol Genet. 2010 Oct 15;19(20):4026-42. doi: 10.1093/hmg/ddq317.

4.
5.

Reduction of BDNF expression in Fmr1 knockout mice worsens cognitive deficits but improves hyperactivity and sensorimotor deficits.

Uutela M, Lindholm J, Louhivuori V, Wei H, Louhivuori LM, Pertovaara A, Akerman K, Castrén E, Castrén ML.

Genes Brain Behav. 2012 Jul;11(5):513-23. doi: 10.1111/j.1601-183X.2012.00784.x.

6.

Mechanism of hyperphagia contributing to obesity in brain-derived neurotrophic factor knockout mice.

Fox EA, Biddinger JE, Jones KR, McAdams J, Worman A.

Neuroscience. 2013 Jan 15;229:176-99. doi: 10.1016/j.neuroscience.2012.09.078.

7.

Disruption of a novel regulatory locus results in decreased Bdnf expression, obesity, and type 2 diabetes in mice.

Sha H, Xu J, Tang J, Ding J, Gong J, Ge X, Kong D, Gao X.

Physiol Genomics. 2007 Oct 22;31(2):252-63.

8.

Central depletion of brain-derived neurotrophic factor in mice results in high bone mass and metabolic phenotype.

Camerino C, Zayzafoon M, Rymaszewski M, Heiny J, Rios M, Hauschka PV.

Endocrinology. 2012 Nov;153(11):5394-405. doi: 10.1210/en.2012-1378.

9.

Mutation screen of the brain derived neurotrophic factor gene (BDNF): identification of several genetic variants and association studies in patients with obesity, eating disorders, and attention-deficit/hyperactivity disorder.

Friedel S, Horro FF, Wermter AK, Geller F, Dempfle A, Reichwald K, Smidt J, Brönner G, Konrad K, Herpertz-Dahlmann B, Warnke A, Hemminger U, Linder M, Kiefl H, Goldschmidt HP, Siegfried W, Remschmidt H, Hinney A, Hebebrand J.

Am J Med Genet B Neuropsychiatr Genet. 2005 Jan 5;132B(1):96-9.

PMID:
15457498
10.

The modifier effect of the BDNF gene in the phenotype of the WAGRO syndrome.

Rodríguez-López R, Pérez JM, Balsera AM, Rodríguez GG, Moreno TH, García de Cáceres M, Serrano MG, Freijo FC, Ruiz JR, Angueira FB, Pérez PM, Estévez MN, Gómez EG.

Gene. 2013 Mar 10;516(2):285-90. doi: 10.1016/j.gene.2012.11.073.

PMID:
23266638
11.

Control of hyperphagia prevents obesity in BDNF heterozygous mice.

Coppola V, Tessarollo L.

Neuroreport. 2004 Dec 3;15(17):2665-8.

PMID:
15570174
12.

The impact of Bdnf gene deficiency to the memory impairment and brain pathology of APPswe/PS1dE9 mouse model of Alzheimer's disease.

Rantamäki T, Kemppainen S, Autio H, Stavén S, Koivisto H, Kojima M, Antila H, Miettinen PO, Kärkkäinen E, Karpova N, Vesa L, Lindemann L, Hoener MC, Tanila H, Castrén E.

PLoS One. 2013 Jul 3;8(7):e68722. doi: 10.1371/journal.pone.0068722.

13.

Brain-derived neurotrophic factor, food intake regulation, and obesity.

Rosas-Vargas H, Martínez-Ezquerro JD, Bienvenu T.

Arch Med Res. 2011 Aug;42(6):482-94. doi: 10.1016/j.arcmed.2011.09.005. Review.

PMID:
21945389
14.

A putative model of overeating and obesity based on brain-derived neurotrophic factor: direct and indirect effects.

Ooi CL, Kennedy JL, Levitan RD.

Behav Neurosci. 2012 Aug;126(4):505-14. doi: 10.1037/a0028600. Review.

PMID:
22687148
15.

Brain-derived neurotrophic factor Val66Met polymorphism and cognitive function in persons with cardiovascular disease.

Szabo AJ, Alosco ML, Miller LA, McGeary JE, Poppas A, Cohen RA, Gunstad J.

Psychogeriatrics. 2013 Dec;13(4):206-12. doi: 10.1111/psyg.12013.

16.

A deletion of the HBII-85 class of small nucleolar RNAs (snoRNAs) is associated with hyperphagia, obesity and hypogonadism.

de Smith AJ, Purmann C, Walters RG, Ellis RJ, Holder SE, Van Haelst MM, Brady AF, Fairbrother UL, Dattani M, Keogh JM, Henning E, Yeo GS, O'Rahilly S, Froguel P, Farooqi IS, Blakemore AI.

Hum Mol Genet. 2009 Sep 1;18(17):3257-65. doi: 10.1093/hmg/ddp263.

17.

Selective deletion of Bdnf in the ventromedial and dorsomedial hypothalamus of adult mice results in hyperphagic behavior and obesity.

Unger TJ, Calderon GA, Bradley LC, Sena-Esteves M, Rios M.

J Neurosci. 2007 Dec 26;27(52):14265-74.

18.

Lack of association between brain-derived neurotrophic factor Val66Met polymorphism and body mass index change over time in healthy adults.

Nikolac Perkovic M, Mustapic M, Pavlovic M, Uzun S, Kozumplik O, Barisic I, Muck-Seler D, Pivac N.

Neurosci Lett. 2013 Jun 17;545:127-31. doi: 10.1016/j.neulet.2013.04.036.

PMID:
23643991
19.

Conditional deletion of brain-derived neurotrophic factor in the postnatal brain leads to obesity and hyperactivity.

Rios M, Fan G, Fekete C, Kelly J, Bates B, Kuehn R, Lechan RM, Jaenisch R.

Mol Endocrinol. 2001 Oct;15(10):1748-57.

PMID:
11579207
20.

The Effects of BDNF Val66Met Gene Polymorphism on Serum BDNF and Cognitive Function in Methamphetamine-Dependent Patients and Normal Controls: A Case-Control Study.

Su H, Tao J, Zhang J, Xie Y, Wang Y, Zhang Y, Han B, Lu Y, Sun H, Wei Y, Zou S, Wu W, Zhang J, Xu K, Zhang X, He J.

J Clin Psychopharmacol. 2015 Oct;35(5):517-24. doi: 10.1097/JCP.0000000000000390.

PMID:
26280836
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