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Items: 1 to 20 of 304

1.

Differential gene expression in mouse primary hepatocytes exposed to the peroxisome proliferator-activated receptor alpha agonists.

Guo L, Fang H, Collins J, Fan XH, Dial S, Wong A, Mehta K, Blann E, Shi L, Tong W, Dragan YP.

BMC Bioinformatics. 2006 Sep 6;7 Suppl 2:S18.

2.

The transcriptional response to a peroxisome proliferator-activated receptor alpha agonist includes increased expression of proteome maintenance genes.

Anderson SP, Howroyd P, Liu J, Qian X, Bahnemann R, Swanson C, Kwak MK, Kensler TW, Corton JC.

J Biol Chem. 2004 Dec 10;279(50):52390-8. Epub 2004 Sep 15.

3.

Plasma mannose-binding lectin is stimulated by PPARα in humans.

Rakhshandehroo M, Stienstra R, de Wit NJ, Bragt MC, Haluzik M, Mensink RP, Müller M, Kersten S.

Am J Physiol Endocrinol Metab. 2012 Mar 1;302(5):E595-602. doi: 10.1152/ajpendo.00299.2011. Epub 2012 Jan 3.

PMID:
22215653
4.

Profiling of gene expression in rat liver and rat primary cultured hepatocytes treated with peroxisome proliferators.

Tamura K, Ono A, Miyagishima T, Nagao T, Urushidani T.

J Toxicol Sci. 2006 Dec;31(5):471-90.

5.

Peroxisome proliferator-activated receptor-alpha gene level differently affects lipid metabolism and inflammation in apolipoprotein E2 knock-in mice.

Lalloyer F, Wouters K, Baron M, Caron S, Vallez E, Vanhoutte J, Baugé E, Shiri-Sverdlov R, Hofker M, Staels B, Tailleux A.

Arterioscler Thromb Vasc Biol. 2011 Jul;31(7):1573-9. doi: 10.1161/ATVBAHA.110.220525. Epub 2011 Apr 7.

6.

Microarray analysis of gene expression changes in mouse liver induced by peroxisome proliferator- activated receptor alpha agonists.

Yamazaki K, Kuromitsu J, Tanaka I.

Biochem Biophys Res Commun. 2002 Jan 25;290(3):1114-22.

PMID:
11798191
7.

Peroxisome proliferator-activated receptor α activation induces hepatic steatosis, suggesting an adverse effect.

Yan F, Wang Q, Xu C, Cao M, Zhou X, Wang T, Yu C, Jing F, Chen W, Gao L, Zhao J.

PLoS One. 2014 Jun 13;9(6):e99245. doi: 10.1371/journal.pone.0099245. eCollection 2014.

8.

Comparative gene expression profiles induced by PPARγ and PPARα/γ agonists in rat hepatocytes.

Rogue A, Renaud MP, Claude N, Guillouzo A, Spire C.

Toxicol Appl Pharmacol. 2011 Jul 1;254(1):18-31. doi: 10.1016/j.taap.2011.04.005. Epub 2011 Apr 14.

PMID:
21515302
9.

Peroxisome proliferator-activated receptor-α agonist, Wy 14,643, improves metabolic indices, steatosis and ballooning in diabetic mice with non-alcoholic steatohepatitis.

Larter CZ, Yeh MM, Van Rooyen DM, Brooling J, Ghatora K, Farrell GC.

J Gastroenterol Hepatol. 2012 Feb;27(2):341-50. doi: 10.1111/j.1440-1746.2011.06939.x.

PMID:
21929649
10.

Bezafibrate induces plasminogen activator inhibitor-1 gene expression in a CLOCK-dependent circadian manner.

Oishi K, Koyanagi S, Matsunaga N, Kadota K, Ikeda E, Hayashida S, Kuramoto Y, Shimeno H, Soeda S, Ohdo S.

Mol Pharmacol. 2010 Jul;78(1):135-41. doi: 10.1124/mol.110.064402. Epub 2010 Apr 16.

11.
12.

Underlying mechanisms of pharmacology and toxicity of a novel PPAR agonist revealed using rodent and canine hepatocytes.

Guo Y, Jolly RA, Halstead BW, Baker TK, Stutz JP, Huffman M, Calley JN, West A, Gao H, Searfoss GH, Li S, Irizarry AR, Qian HR, Stevens JL, Ryan TP.

Toxicol Sci. 2007 Apr;96(2):294-309. Epub 2007 Jan 25.

PMID:
17255113
13.

Chimeric mice with hepatocyte-humanized liver as an appropriate model to study human peroxisome proliferator-activated receptor-α.

Tateno C, Yamamoto T, Utoh R, Yamasaki C, Ishida Y, Myoken Y, Oofusa K, Okada M, Tsutsui N, Yoshizato K.

Toxicol Pathol. 2015 Feb;43(2):233-48. doi: 10.1177/0192623314544378. Epub 2014 Aug 8.

PMID:
25107573
14.

Statin induction of liver fatty acid-binding protein (L-FABP) gene expression is peroxisome proliferator-activated receptor-alpha-dependent.

Landrier JF, Thomas C, Grober J, Duez H, Percevault F, Souidi M, Linard C, Staels B, Besnard P.

J Biol Chem. 2004 Oct 29;279(44):45512-8. Epub 2004 Aug 27.

15.

Diminished hepatocellular proliferation in mice humanized for the nuclear receptor peroxisome proliferator-activated receptor alpha.

Cheung C, Akiyama TE, Ward JM, Nicol CJ, Feigenbaum L, Vinson C, Gonzalez FJ.

Cancer Res. 2004 Jun 1;64(11):3849-54.

16.

Characterization of peroxisome proliferator-activated receptor alpha--independent effects of PPARalpha activators in the rodent liver: di-(2-ethylhexyl) phthalate also activates the constitutive-activated receptor.

Ren H, Aleksunes LM, Wood C, Vallanat B, George MH, Klaassen CD, Corton JC.

Toxicol Sci. 2010 Jan;113(1):45-59. doi: 10.1093/toxsci/kfp251. Epub 2009 Oct 22.

17.

Transcription coactivator PBP, the peroxisome proliferator-activated receptor (PPAR)-binding protein, is required for PPARalpha-regulated gene expression in liver.

Jia Y, Qi C, Kashireddi P, Surapureddi S, Zhu YJ, Rao MS, Le Roith D, Chambon P, Gonzalez FJ, Reddy JK.

J Biol Chem. 2004 Jun 4;279(23):24427-34. Epub 2004 Mar 29.

18.

Gene expression profiling of the PPAR-alpha agonist ciprofibrate in the cynomolgus monkey liver.

Cariello NF, Romach EH, Colton HM, Ni H, Yoon L, Falls JG, Casey W, Creech D, Anderson SP, Benavides GR, Hoivik DJ, Brown R, Miller RT.

Toxicol Sci. 2005 Nov;88(1):250-64. Epub 2005 Aug 4.

PMID:
16081524
19.

Comparative gene expression profiles induced by PPARγ and PPARα/γ agonists in human hepatocytes.

Rogue A, Lambert C, Jossé R, Antherieu S, Spire C, Claude N, Guillouzo A.

PLoS One. 2011 Apr 18;6(4):e18816. doi: 10.1371/journal.pone.0018816.

20.

Human peroxisome proliferator-activated receptor alpha (PPARalpha) supports the induction of peroxisome proliferation in PPARalpha-deficient mouse liver.

Yu S, Cao WQ, Kashireddy P, Meyer K, Jia Y, Hughes DE, Tan Y, Feng J, Yeldandi AV, Rao MS, Costa RH, Gonzalez FJ, Reddy JK.

J Biol Chem. 2001 Nov 9;276(45):42485-91. Epub 2001 Sep 10.

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