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Items: 1 to 20 of 428

1.

GB virus B disrupts RIG-I signaling by NS3/4A-mediated cleavage of the adaptor protein MAVS.

Chen Z, Benureau Y, Rijnbrand R, Yi J, Wang T, Warter L, Lanford RE, Weinman SA, Lemon SM, Martin A, Li K.

J Virol. 2007 Jan;81(2):964-76. Epub 2006 Nov 8.

2.

Functional and therapeutic analysis of hepatitis C virus NS3.4A protease control of antiviral immune defense.

Johnson CL, Owen DM, Gale M Jr.

J Biol Chem. 2007 Apr 6;282(14):10792-803. Epub 2007 Feb 8.

3.

Virus-specific cofactor requirement and chimeric hepatitis C virus/GB virus B nonstructural protein 3.

Butkiewicz N, Yao N, Zhong W, Wright-Minogue J, Ingravallo P, Zhang R, Durkin J, Standring DN, Baroudy BM, Sangar DV, Lemon SM, Lau JY, Hong Z.

J Virol. 2000 May;74(9):4291-301.

4.

Recruitment of an interferon molecular signaling complex to the mitochondrial membrane: disruption by hepatitis C virus NS3-4A protease.

Hiscott J, Lacoste J, Lin R.

Biochem Pharmacol. 2006 Nov 30;72(11):1477-84. Epub 2006 Jul 31.

PMID:
16876765
5.

A comparative analysis of the substrate permissiveness of HCV and GBV-B NS3/4A proteases reveals genetic evidence for an interaction with NS4B protein during genome replication.

Benureau Y, Warter L, Malcolm BA, Martin A.

Virology. 2010 Oct 25;406(2):228-40. doi: 10.1016/j.virol.2010.07.014. Epub 2010 Aug 11.

6.

Hepatitis C virus NS2 and NS3/4A proteins are potent inhibitors of host cell cytokine/chemokine gene expression.

Kaukinen P, Sillanpää M, Kotenko S, Lin R, Hiscott J, Melén K, Julkunen I.

Virol J. 2006 Sep 1;3:66.

7.
8.

Dissociation of a MAVS/IPS-1/VISA/Cardif-IKKepsilon molecular complex from the mitochondrial outer membrane by hepatitis C virus NS3-4A proteolytic cleavage.

Lin R, Lacoste J, Nakhaei P, Sun Q, Yang L, Paz S, Wilkinson P, Julkunen I, Vitour D, Meurs E, Hiscott J.

J Virol. 2006 Jun;80(12):6072-83.

9.

Control of innate immune signaling and membrane targeting by the Hepatitis C virus NS3/4A protease are governed by the NS3 helix α0.

Horner SM, Park HS, Gale M Jr.

J Virol. 2012 Mar;86(6):3112-20. doi: 10.1128/JVI.06727-11. Epub 2012 Jan 11.

10.

Hepatitis C virus variants resistant to macrocyclic NS3-4A inhibitors subvert IFN-β induction by efficient MAVS cleavage.

Welsch C, Haselow K, Gouttenoire J, Schneider M, Morikawa K, Martinez Y, Susser S, Sarrazin C, Zeuzem S, Antes I, Moradpour D, Lange CM.

J Hepatol. 2015 Apr;62(4):779-84. doi: 10.1016/j.jhep.2014.11.009. Epub 2014 Nov 21.

PMID:
25463536
11.

Restoration of the activated Rig-I pathway in hepatitis C virus (HCV) replicon cells by HCV protease, polymerase, and NS5A inhibitors in vitro at clinically relevant concentrations.

Kalkeri G, Lin C, Gopilan J, Sloan K, Rijnbrand R, Kwong AD.

Antimicrob Agents Chemother. 2013 Sep;57(9):4417-26. doi: 10.1128/AAC.00399-13. Epub 2013 Jul 8.

12.

Induction of IRF-3 and IRF-7 phosphorylation following activation of the RIG-I pathway.

Paz S, Sun Q, Nakhaei P, Romieu-Mourez R, Goubau D, Julkunen I, Lin R, Hiscott J.

Cell Mol Biol (Noisy-le-grand). 2006 May 15;52(1):17-28.

PMID:
16914100
13.

Hepacivirus NS3/4A Proteases Interfere with MAVS Signaling in both Their Cognate Animal Hosts and Humans: Implications for Zoonotic Transmission.

Anggakusuma, Brown RJ, Banda DH, Todt D, Vieyres G, Steinmann E, Pietschmann T.

J Virol. 2016 Nov 14;90(23):10670-10681. Print 2016 Dec 1.

14.

Cleavage of the IPS-1/Cardif/MAVS/VISA does not inhibit T cell-mediated elimination of hepatitis C virus non-structural 3/4A-expressing hepatocytes.

Ahlén G, Derk E, Weiland M, Jiao J, Rahbin N, Aleman S, Peterson DL, Pokrovskaja K, Grandér D, Frelin L, Sällberg M.

Gut. 2009 Apr;58(4):560-9. doi: 10.1136/gut.2007.147264. Epub 2008 Aug 8.

15.

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus.

Meylan E, Curran J, Hofmann K, Moradpour D, Binder M, Bartenschlager R, Tschopp J.

Nature. 2005 Oct 20;437(7062):1167-72. Epub 2005 Sep 21.

PMID:
16177806
16.

Hepatitis C virus NS4B protein targets STING and abrogates RIG-I-mediated type I interferon-dependent innate immunity.

Nitta S, Sakamoto N, Nakagawa M, Kakinuma S, Mishima K, Kusano-Kitazume A, Kiyohashi K, Murakawa M, Nishimura-Sakurai Y, Azuma S, Tasaka-Fujita M, Asahina Y, Yoneyama M, Fujita T, Watanabe M.

Hepatology. 2013 Jan;57(1):46-58. doi: 10.1002/hep.26017.

PMID:
22911572
17.

The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses.

Yoneyama M, Kikuchi M, Natsukawa T, Shinobu N, Imaizumi T, Miyagishi M, Taira K, Akira S, Fujita T.

Nat Immunol. 2004 Jul;5(7):730-7. Epub 2004 Jun 20.

PMID:
15208624
18.
19.

MDA5 plays a critical role in interferon response during hepatitis C virus infection.

Cao X, Ding Q, Lu J, Tao W, Huang B, Zhao Y, Niu J, Liu YJ, Zhong J.

J Hepatol. 2015 Apr;62(4):771-8. doi: 10.1016/j.jhep.2014.11.007. Epub 2014 Nov 21.

PMID:
25463548
20.

Mitochondrial antiviral signaling protein plays a major role in induction of the fish innate immune response against RNA and DNA viruses.

Biacchesi S, LeBerre M, Lamoureux A, Louise Y, Lauret E, Boudinot P, Brémont M.

J Virol. 2009 Aug;83(16):7815-27. doi: 10.1128/JVI.00404-09. Epub 2009 May 27.

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