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Items: 1 to 20 of 218

1.

TLR4 links innate immunity and fatty acid-induced insulin resistance.

Shi H, Kokoeva MV, Inouye K, Tzameli I, Yin H, Flier JS.

J Clin Invest. 2006 Nov;116(11):3015-25. Epub 2006 Oct 19.

2.

From chronic overnutrition to insulin resistance: the role of fat-storing capacity and inflammation.

Lionetti L, Mollica MP, Lombardi A, Cavaliere G, Gifuni G, Barletta A.

Nutr Metab Cardiovasc Dis. 2009 Feb;19(2):146-52. doi: 10.1016/j.numecd.2008.10.010. Epub 2009 Jan 25. Review.

PMID:
19171470
3.

Signaling mechanisms involved in altered function of macrophages from diet-induced obese mice affect immune responses.

Zhou Q, Leeman SE, Amar S.

Proc Natl Acad Sci U S A. 2009 Jun 30;106(26):10740-5. doi: 10.1073/pnas.0904412106. Epub 2009 Jun 17.

4.
5.

The c-Jun N-terminal kinase mediates the induction of oxidative stress and insulin resistance by palmitate and toll-like receptor 2 and 4 ligands in 3T3-L1 adipocytes.

Davis JE, Gabler NK, Walker-Daniels J, Spurlock ME.

Horm Metab Res. 2009 Jul;41(7):523-30. doi: 10.1055/s-0029-1202852. Epub 2009 Mar 10.

PMID:
19277946
6.

Fetuin-A acts as an endogenous ligand of TLR4 to promote lipid-induced insulin resistance.

Pal D, Dasgupta S, Kundu R, Maitra S, Das G, Mukhopadhyay S, Ray S, Majumdar SS, Bhattacharya S.

Nat Med. 2012 Aug;18(8):1279-85. doi: 10.1038/nm.2851. Epub 2012 Jul 29.

PMID:
22842477
7.

A synthetic analog of alpha-galactosylceramide induces macrophage activation via the TLR4-signaling pathways.

Hung LC, Lin CC, Hung SK, Wu BC, Jan MD, Liou SH, Fu SL.

Biochem Pharmacol. 2007 Jun 15;73(12):1957-70. Epub 2007 Mar 12.

PMID:
17445776
8.

Toll-like receptor 4 initiates an innate immune response to lipopolysaccharide in human conjunctival epithelial cells.

Chung SH, Kweon MN, Lee HK, Choi SI, Yang JY, Kim EK.

Exp Eye Res. 2009 Jan;88(1):49-56. doi: 10.1016/j.exer.2008.09.017. Epub 2008 Oct 9.

PMID:
18951893
9.

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance.

Xu H, Barnes GT, Yang Q, Tan G, Yang D, Chou CJ, Sole J, Nichols A, Ross JS, Tartaglia LA, Chen H.

J Clin Invest. 2003 Dec;112(12):1821-30.

10.

Activation of Toll-like receptor 4 is associated with insulin resistance in adipocytes.

Song MJ, Kim KH, Yoon JM, Kim JB.

Biochem Biophys Res Commun. 2006 Aug 4;346(3):739-45. Epub 2006 Jun 6.

PMID:
16781673
11.

Macrophage-secreted factors induce adipocyte inflammation and insulin resistance.

Permana PA, Menge C, Reaven PD.

Biochem Biophys Res Commun. 2006 Mar 10;341(2):507-14. Epub 2006 Jan 13.

PMID:
16427608
13.

Monocyte chemotactic protein-1 and its role in insulin resistance.

Sell H, Eckel J.

Curr Opin Lipidol. 2007 Jun;18(3):258-62. Review.

PMID:
17495598
14.

Advanced glycation end-product of low density lipoprotein activates the toll-like 4 receptor pathway implications for diabetic atherosclerosis.

Hodgkinson CP, Laxton RC, Patel K, Ye S.

Arterioscler Thromb Vasc Biol. 2008 Dec;28(12):2275-81. doi: 10.1161/ATVBAHA.108.175992. Epub 2008 Sep 25.

15.

Toll-like receptor 2 and 4 ligation results in complex altered cytokine profiles early and late after burn injury.

Cairns BA, Barnes CM, Mlot S, Meyer AA, Maile R.

J Trauma. 2008 Apr;64(4):1069-77; discussion 1077-8. doi: 10.1097/TA.0b013e318166b7d9.

PMID:
18404077
16.

Attenuation of obesity-induced adipose tissue inflammation in C3H/HeJ mice carrying a Toll-like receptor 4 mutation.

Suganami T, Mieda T, Itoh M, Shimoda Y, Kamei Y, Ogawa Y.

Biochem Biophys Res Commun. 2007 Mar 2;354(1):45-9. Epub 2007 Jan 2.

PMID:
17210129
17.

Bacterial lipopolysaccharide induces increased expression of toll-like receptor (TLR) 4 and downstream TLR signaling molecules in bovine mammary epithelial cells.

Ibeagha-Awemu EM, Lee JW, Ibeagha AE, Bannerman DD, Paape MJ, Zhao X.

Vet Res. 2008 Mar-Apr;39(2):11. Epub 2007 Dec 21.

18.

Deficiencies of myeloid differentiation factor 88, Toll-like receptor 2 (TLR2), or TLR4 produce specific defects in macrophage cytokine secretion induced by Helicobacter pylori.

Obonyo M, Sabet M, Cole SP, Ebmeyer J, Uematsu S, Akira S, Guiney DG.

Infect Immun. 2007 May;75(5):2408-14. Epub 2007 Mar 12.

19.

Two neisseria meningitidis strains with different ability to stimulate toll-like receptor 4 through the MyD88-independent pathway.

Mogensen TH, Paludan SR, Kilian M, Ƙstergaard L.

Scand J Immunol. 2006 Dec;64(6):646-54.

20.

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