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Items: 1 to 20 of 231

1.

A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration.

Yang Z, Camp NJ, Sun H, Tong Z, Gibbs D, Cameron DJ, Chen H, Zhao Y, Pearson E, Li X, Chien J, Dewan A, Harmon J, Bernstein PS, Shridhar V, Zabriskie NA, Hoh J, Howes K, Zhang K.

Science. 2006 Nov 10;314(5801):992-3. Epub 2006 Oct 19.

2.

Analysis of six genetic risk factors highly associated with AMD in the region surrounding ARMS2 and HTRA1 on chromosome 10, region q26.

Hadley D, Orlin A, Brown G, Brucker AJ, Ho AC, Regillo CD, Donoso LA, Tian L, Kaderli B, Stambolian D.

Invest Ophthalmol Vis Sci. 2010 Apr;51(4):2191-6. doi: 10.1167/iovs.09-3798. Epub 2009 Nov 20.

PMID:
19933195
3.

Association of the HTRA1 -625G>A promoter gene polymorphism with exudative age-related macular degeneration in a Central European population.

Weger M, Renner W, Steinbrugger I, Köfer K, Wedrich A, Groselj-Strele A, El-Shabrawi Y, Schmut O, Haas A.

Mol Vis. 2007 Jul 24;13:1274-9.

PMID:
17679948
4.

A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration.

Kanda A, Chen W, Othman M, Branham KE, Brooks M, Khanna R, He S, Lyons R, Abecasis GR, Swaroop A.

Proc Natl Acad Sci U S A. 2007 Oct 9;104(41):16227-32. Epub 2007 Sep 20.

5.

HTRA1 promoter polymorphism in wet age-related macular degeneration.

Dewan A, Liu M, Hartman S, Zhang SS, Liu DT, Zhao C, Tam PO, Chan WM, Lam DS, Snyder M, Barnstable C, Pang CP, Hoh J.

Science. 2006 Nov 10;314(5801):989-92. Epub 2006 Oct 19.

6.
7.

HTRA1 variant increases risk to neovascular age-related macular degeneration in Chinese population.

Lu F, Hu J, Zhao P, Lin Y, Yang Y, Liu X, Fan Y, Chen B, Liao S, Du Q, Lei C, Cameron DJ, Zhang K, Yang Z.

Vision Res. 2007 Nov;47(24):3120-3. Epub 2007 Sep 27.

8.

Variants in the 10q26 gene cluster (LOC387715 and HTRA1) exhibit enhanced risk of age-related macular degeneration along with CFH in Indian patients.

Kaur I, Katta S, Hussain A, Hussain N, Mathai A, Narayanan R, Hussain A, Reddy RK, Majji AB, Das T, Chakrabarti S.

Invest Ophthalmol Vis Sci. 2008 May;49(5):1771-6. doi: 10.1167/iovs.07-0560.

PMID:
18436811
9.

Analyses of single nucleotide polymorphisms and haplotype linkage of LOC387715 and the HTRA1 gene in exudative age-related macular degeneration in a Chinese cohort.

Jiang H, Qu Y, Dang G, Zhang X, Yin N, Zhang Y, Bi H, Pan X, Xu X, Zhou F, Dai H.

Retina. 2009 Jul-Aug;29(7):974-9. doi: 10.1097/IAE.0b013e3181a3b90e.

PMID:
19491722
10.

LOC387715/HTRA1 variants in polypoidal choroidal vasculopathy and age-related macular degeneration in a Japanese population.

Kondo N, Honda S, Ishibashi K, Tsukahara Y, Negi A.

Am J Ophthalmol. 2007 Oct;144(4):608-12. Epub 2007 Aug 9.

PMID:
17692272
11.

Association of the HTRA1 gene variant with age-related macular degeneration in the Japanese population.

Mori K, Horie-Inoue K, Kohda M, Kawasaki I, Gehlbach PL, Awata T, Yoneya S, Okazaki Y, Inoue S.

J Hum Genet. 2007;52(7):636-41. Epub 2007 Jun 14.

PMID:
17568988
12.

Further mapping of 10q26 supports strong association of HTRA1 polymorphisms with age-related macular degeneration.

Gibbs D, Yang Z, Constantine R, Ma X, Camp NJ, Yang X, Chen H, Jorgenson A, Hau V, Dewan A, Zeng J, Harmon J, Buehler J, Brand JM, Hoh J, Cameron DJ, Dixit M, Tong Z, Zhang K.

Vision Res. 2008 Feb;48(5):685-9. doi: 10.1016/j.visres.2007.10.022. Epub 2008 Jan 22.

13.

PLEKHA1-LOC387715-HTRA1 polymorphisms and exudative age-related macular degeneration in the French population.

Leveziel N, Souied EH, Richard F, Barbu V, Zourdani A, Morineau G, Zerbib J, Coscas G, Soubrane G, Benlian P.

Mol Vis. 2007 Nov 26;13:2153-9.

PMID:
18079691
14.

Phenotype and genotype characteristics of age-related macular degeneration in a Japanese population.

Mori K, Horie-Inoue K, Gehlbach PL, Takita H, Kabasawa S, Kawasaki I, Ohkubo T, Kurihara S, Iizuka H, Miyashita Y, Katayama S, Awata T, Yoneya S, Inoue S.

Ophthalmology. 2010 May;117(5):928-38. doi: 10.1016/j.ophtha.2009.10.001. Epub 2010 Feb 4.

PMID:
20132989
15.

HTRA1 promoter polymorphism predisposes Japanese to age-related macular degeneration.

Yoshida T, DeWan A, Zhang H, Sakamoto R, Okamoto H, Minami M, Obazawa M, Mizota A, Tanaka M, Saito Y, Takagi I, Hoh J, Iwata T.

Mol Vis. 2007 Apr 4;13:545-8.

16.

Association of HTRA1 polymorphism and bilaterality in advanced age-related macular degeneration.

Chen H, Yang Z, Gibbs D, Yang X, Hau V, Zhao P, Ma X, Zeng J, Luo L, Pearson E, Constantine R, Kaminoh Y, Harmon J, Tong Z, Stratton CA, Cameron DJ, Tang S, Zhang K.

Vision Res. 2008 Feb;48(5):690-4. doi: 10.1016/j.visres.2007.10.014.

17.

Meta-analysis of the association of the HTRA1 polymorphisms with the risk of age-related macular degeneration.

Chen W, Xu W, Tao Q, Liu J, Li X, Gan X, Hu H, Lu Y.

Exp Eye Res. 2009 Sep;89(3):292-300. doi: 10.1016/j.exer.2008.10.017. Epub 2008 Nov 6. Review.

PMID:
19026638
18.

Joint effects of polymorphisms in the HTRA1, LOC387715/ARMS2, and CFH genes on AMD in a Caucasian population.

Francis PJ, Zhang H, Dewan A, Hoh J, Klein ML.

Mol Vis. 2008 Aug 4;14:1395-400.

19.

Characterization of the 10q26-orthologue in rhesus monkeys corroborates a functional connection between ARMS2 and HTRA1.

Pahl L, Spangenberg A, Schubert S, Schönmann U, Schmidtke J, Stuhrmann M.

Exp Eye Res. 2012 May;98:75-8. doi: 10.1016/j.exer.2012.03.007. Epub 2012 Mar 21.

PMID:
22465519
20.

Association analysis of CFH, C2, BF, and HTRA1 gene polymorphisms in Chinese patients with polypoidal choroidal vasculopathy.

Lee KY, Vithana EN, Mathur R, Yong VH, Yeo IY, Thalamuthu A, Lee MW, Koh AH, Lim MC, How AC, Wong DW, Aung T.

Invest Ophthalmol Vis Sci. 2008 Jun;49(6):2613-9. doi: 10.1167/iovs.07-0860.

PMID:
18515590

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